Abstract
Cardiovascular disease is a major cause of morbidity and mortality worldwide, hypertension being one of their most prevalent risk factors. Information on health related quality of life (QOL) of hypertensive individuals in Lebanon is lacking. Our objectives were to evaluate QOL of hypertensive patients compared with non-hypertensive subjects and to suggest possible predictors of QOL in Lebanon. We conducted a case control study among individuals visiting outpatient clinics. Quality of life was assessed using the eight item (SF-8) questionnaire administered face to face to the study population, applied to hypertensive (N = 224) and non-hypertensive control (N = 448) groups. Hypertensive patients presented lower QOL scores in all domains, particularly in case of high administration frequency and occurrence of drug related side effects. Among hypertensive patients, QOL was significantly decreased with the presence of comorbidities (ß = −13.865, p = 0.054), daily frequency of antihypertensive medications (ß = −8.196, p< 0.001), presence of drug side-effects (ß = −19.262, p = 0.031), older age (ß = −0.548, p < 0.001), female gender (ß = −21.363, p = 0.05), lower education (ß = −22.949, p = 0.006), and cigarettes smoked daily (ß = –0.726, p> 0.001); regular sport activity (ß = 23.15, p < 0.001) significantly increased quality of life. These findings indicate the necessity for health professionals to take these factors into account when treating hypertensive patients, and to tackle special subgroups with attention to their deteriorated QOL.
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Nogueira D, Faerstein E, Coeli CM, Chor D, Lopes CS, Werneck GL. Reconhecimento, tratamento e controle da hipertensão arterial: Estudo Pró-Saúde Brasil. Rev Panam Salud Pública 2010;27(2): 103–9.
Rosini N, Machado MJ, Xavier HT. Estudo da prevaléncia e multiplicidade de fatores de risco cardiovascular em hipertensos do município de Brusque, SC. Arq Bras Cardiol 2006;86(3):219–22.
World Health Organization: Causes of Death, Geneva, 2008. Available at: http://www.who.int/mediacentre/fact-sheets/fs317/en/.
Sociedade Brasileira de Cardiología. Sociedade Brasileira de Hipertensão, Sociedade Brasileira de Nefrologia. VI Diretrizes brasileiras de hipertensao. Arq Bras Cardiol 2010;95(1):1–51 (Suppl. 1).
Lim SS, Vos T, Flaxman AD, Danaei G, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380(9859):2224–60.
World Health Organization, WHO (1998): Global burden of diabetes. Press Release WHO/63. September 14, 1998 Available at: http://www.who.int/inf-pr-1998/en/pr98-63.html.
Stewart AL et al. Functional status and well-being of patients with chronic conditions. Results from the Medical Outcomes Study. J Am Med Assoc 1989;262(7):907–13.
Plaisted CS et al. The effects of dietary patterns on quality of life: a substudy of the Dietary Approaches to Stop Hypertension trial. J Am Diet Assoc 1999;99(Suppl. 8): S84–9.
Roca-Cusachs A, Dalfo A, Badia X, Aristegui I, Roset M. Relation between clinical and therapeutic variables and quality of life in hypertension. J Hypertens 2001;19(10):1913–9.
Li W, Liu L, Puente JG, Li Y, Jiang X, Jin S, et al. Hypertension and health related quality of life: an epidemiological study in patients attending hospital clinics in China. J Hypertens 2005;23(9): 1667–76.
Bardage M, Isacson DGL. Hypertension and health related quality of life: epidemiological studies in Sweden. J Clin Epidemiol 2001;54:172–81.
Ware JE, Kosinki M, Dewey J, Gandek B: How to Score and Interpret Single-Item Health Status Measures: A Manual for Users of the SF-8 Health Survey. Boston, QualityMetric Inc., 2001; 4–8.
Tohme RA, Jurjus AR, Estephan A. The prevalence of hypertension and its association with other cardiovascular disease risk factors in a representative sample of the Lebanese population. J Hum Hypertens 2005;19(11):861–8.
Mafawzy M, Mokhtar N, Wan Mohammad WB. Hypertension and associated cardiovascular risk factors in Kelantan. Med J Malaysia 2003;58(4):556–64.
Tanuseputro P et al. Canadian cardiovascular outcomes research team, risk factors for cardiovascular disease in Canada. Can J Cardiol 2003; 19(11): 1249–59.
Wood S. JNC8 at last! Guidelines ease up on BP thresholds, drug choices. Heartwire [serial online]. Assessed December 30, 2013. Available at: http://www.medscape.com/viewarticle/817991.
The World Health Organization Quality of Life Assessment (WHOQOL): development and general psychometric properties. Soc Sci Med 1998; 46(12): 1569–5.
Lohr KN, Aaronson NK, Alonso J, Burnam MA, Patrick DL, Perrin EB, Roberts JS. Evaluating quality-of-life and health status instruments: development of scientific review criteria. Clin Ther 1996;18(5):979–92.
SF-8™ Health Survey Scoring Demonstration available at: http://www.sf-36.org/demos/SF-8.html and http://www.qualitymetric.com/WhatWeDo/GenericHealthSurveys/SF8HealthSurvey/tabid/187/Default.aspx.
Brunye T, Mahoney C, Rapp D, Ditman T, Taylor H. Caffeine enhances real-world language processing: evidence from a proofreading task. J Exp Psychol Appl 2012;18:95–108.
Wang R, Zhao Y, He X, Ma X, Yan X, Sun Y, et al. Impact of hypertension on health-related quality of life in a population-based study in Shangai, China. Public Health 2009;123(8):534–9.
Wilson D, Parsons J, Wakefield M. The health-related quality-of-life of never smokers, ex-smokers, and light, moderate, and heavy smokers. Prev Med 1999;29:139–44.
Terry Hartley R, Sung Bong Hee, Pincomb Gwendolyn A, Whitsett Thomas L, Wilson Michael F, Lovallo William R. Hypertension risk status and effect of caffeine on blood pressure. Hypertension 2000;36:137–41.
Nancy J Aburto, Anna Ziolkovska, Lee Hooper, Paul Elliott, Francesco P Cappuccio, Joerg J Meerpohl. Effect of lower sodium intake on health: systematic review and metaanalyses BMJ 2013; 346 doi https://doi.org/10.1136/bmj.f1326 (Published 4 April 2013).
Tedesco MA, Ratti G, Mennella S, et al. Comparison of losartan and hydrochlorothiazide on cognitive function and quality of life in hypertensive patients. Am J Hypertens 1999;12:1130–4.
Kawecka-Jaszcz K, Klocek M, Tobiasz-Adamczyk B. Quality of life in patients with arterial hypertension. In: Hhjh M, editor. Quality of Life in Cardiovascular Diseases. Termedia Wydawnictwo Medyczne; 2006. p. 122.
Rolnick J, Pawloski P, et al. Patient characteristics associated with medication adherence. Clin Med Res 2013;11(2):54–65.
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Khalifeh, M., Salameh, P., Hajje, A.A. et al. Hypertension in the Lebanese adults: Impact on health related quality of life. J Epidemiol Glob Health 5, 327–336 (2015). https://doi.org/10.1016/j.jegh.2015.02.003
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DOI: https://doi.org/10.1016/j.jegh.2015.02.003