Abstract
Self-assembled supramolecular host-guest complexes have been characterized by electrospray ionization mass spectrometry. The spectra obtained by use of a Q-TOF instrument equipped with a Z-spray ion source show primarily the 3- and 4- charge states of the assemblies. The assemblies have the general formula [guest ⊂ Ga4 L 6]11− where L represents the chelating bidentate catechol ligand 1,5-bis(2′,3′-dihydroxy-benzamido)naphthalene and guests are tetramethyl ammonium (Me4N+), tetraethyl ammonium (Et4N+), tetra-n-propyl ammonium (Pr4N+) and decamethylcobaltocenium (Cp*2Co+) cations. For the first time, the mass spectrum of the empty assembly [Ga4 L 6]12− is reported. This article also reports that provided the electrospray ion source is capable of preserving noncovalent interactions, it is possible to observe host-guest complexes containing both weak binding guests as well as sterically demanding guests in the mass spectra. The present data suggest that electrospray mass spectrometry is a powerful tool for characterization of supramolecular host-guest complexes.
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Published online February 7, 2006
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Andersen, U.N., Seeber, G., Fiedler, D. et al. Characterization of self-assembled supramolecular [Ga4L6] host-guest complexes by electrospray ionization mass spectrometry. The official journal of The American Society for Mass Spectrometry 17, 292–296 (2006). https://doi.org/10.1016/j.jasms.2005.10.011
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DOI: https://doi.org/10.1016/j.jasms.2005.10.011