Abstract
Recent studies have demonstrated the biological importance of the interaction of nitric oxide with proteins such as cytochrome-c or hemoglobin. In particular, the possibility that the nitrosonium cation, NO+, could reversibly bind to sulfide atom type was proposed. At pH values of biological relevance, nitrosation was proposed to occur through the action of NO+ carriers such as nitrosothiols or nitrosamines. In this context, the gas phase chemistry of protonated nitrosothiols is studied in the present work by a combination of mass spectrometry and computational methods.
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Published online January 15, 2004
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Gerbaux, P., Wantier, P. & Flammang, R. Nitrosation of thiols and thioethers in the gas phase: A combined theoretical and experimental study. J Am Soc Mass Spectrom 15, 344–355 (2004). https://doi.org/10.1016/j.jasms.2003.10.016
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DOI: https://doi.org/10.1016/j.jasms.2003.10.016