Abstract
The collision-induced dissociation characteristics of amidinated and unmodified tryptic peptides are compared using an ion trap mass spectrometer with both electrospray ionization and matrix-assisted laser/desorption ionization (MALDI). Several fragmentation pathways in a number of tryptic peptides of various precursor charge states are found to be enhanced. The additional information conveyed by the observed fragment ions should facilitate protein identifications.
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Published online December 4, 2003
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Beardsley, R.L., Reilly, J.P. Fragmentation of amidinated peptide ions. J Am Soc Mass Spectrom 15, 158–167 (2004). https://doi.org/10.1016/j.jasms.2003.10.007
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DOI: https://doi.org/10.1016/j.jasms.2003.10.007