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Novel two-step resection for lesions between the middle hepatic vein and vena cava which allows the middle hepatic vein to be preserved

  • Published:
Journal of Gastrointestinal Surgery

Abstract

Patients with bilobar colorectal cancer metastases to the liver present a unique problem in terms of resection. They sometimes require a staged approach to resection that takes advantage of the liver’s ability to regenerate, as well as the newer chemotherapeutic agents (e.g., oxaloplatin, irinotecan (CPT-11), and bevacizumab) that have become available. In cases of multiple bilobar metastases, if segment IV is clear of tumor, a left lateral segmentectomy (LLS) can be performed, followed several months later by a formal right hepatectomy. The remnant liver composed of the hypertrophied segment IV is drained by the middle hepatic vein (MHV). In this context, patients with lesions between the origin of the MHV and the inferior vena cava (IVC) present a particularly difficult problem. Conventional excision would require an extended hepatectomy and division of the MHV along with either the right or left hepatic veins (RHV, LHV). This would make it impossible to continue with a formal resection of the remaining lesions in the contralateral liver without sacrificing the sole remaining hepatic vein. We present a novel two-step hepatectomy for lesions between the MHV and the IVC that allows the MHV to be preserved and all lesions to be resected.

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References

  1. Parikh AA, Gentner B, Wu TT, et al. Perioperative complications in patients undergoing major liver resection with or without neoadjuvant chemotherapy. J GASTROINTEST SURG 2003;7(8):1082–1088.

    Article  PubMed  Google Scholar 

  2. Jatzko G, Wette V, Muller M, et al. Simultaneous resection of colorectal carcinoma and synchronous liver metastases in a district hospital. Int J Colorectal Dis 1991;6(2):111–114.

    Article  PubMed  CAS  Google Scholar 

  3. Zelek L, Bugat R, Cherqui D, et al. Multimodal therapy with intravenous biweekly leucovorin, 5-fluorouracil and irinotecan combined with hepatic arterial infusion pirarubicin in non-resectable hepatic metastases from colorectal cancer (a European Association for Research in Oncology trial). Ann Oncol 2003;14(10):1537–1542.

    Article  PubMed  CAS  Google Scholar 

  4. Weiss L, Grundmann E, Torhorst J, et al. Haematogenous metastatic patterns in colonic carcinoma: an analysis of 1541 necropsies. J Pathol 1986;150(3):195–203.

    Article  PubMed  CAS  Google Scholar 

  5. Scheele J, Stangl R, Altendorf-Hofmann A. Hepatic metastases from colorectal carcinoma: impact of surgical resection on the natural history. Br J Surg 1990;77(11):1241–1246.

    Article  PubMed  CAS  Google Scholar 

  6. Scheele J, Altendorf-Hofmann A, Stangl R, et al. Chirurgische Resektion kolorektaler lebermetastasen: Goldstandard für solitäre und resekable herde (Surgical resection of colorectal liver metastases: Gold standard for solitary and radically resectable lesions). Swiss Surgery 1996;4(Suppl 4):4–17.

    PubMed  Google Scholar 

  7. Nordlinger B, Guiguet M, Vaillant JC, et al. Surgical resection of colorectal carcinoma metastases to the liver. A prognostic scoring system to improve case selection, based on 1568 patients. Cancer 1996;77(7):1254–1262.

    Article  PubMed  CAS  Google Scholar 

  8. Jamison RL, Donohue JH, Nagorney DM, et al. Hepatic resection for metastatic colorectal cancer results in cure for some patients. Arch Surg 1997;132(5):505–510.

    PubMed  CAS  Google Scholar 

  9. Taylor M, Forster J, Langer B, et al. A study of prognostic factors for hepatic resection for colorectal metastases. Am J Surg 1997;173(6):467–471.

    Article  PubMed  CAS  Google Scholar 

  10. Jenkins LT, Millikan KW, Bines SD, et al. Hepatic resection for metastatic colorectal cancer. Am Surg 1997;63(7):605–610.

    PubMed  CAS  Google Scholar 

  11. Rees M, Plant G, Bygrave S. Late results justify resection for multiple hepatic metastases from colorectal cancer. Br J Surg 1997;84(8):1136–1140.

    Article  PubMed  CAS  Google Scholar 

  12. Ohlsson B, Stenram U, Tranberg KG. Resection of colorectal liver metastases: 25-year experience. World J Surg 1998; 22(3):268–276.

    Article  PubMed  CAS  Google Scholar 

  13. Ambiru S, Miyazaki M, Isono T, et al. Hepatic resection for colorectal metastases: analysis of prognostic factors. Dis Colon Rectum 1999;42(5):632–639.

    Article  PubMed  CAS  Google Scholar 

  14. Bradley AL, Chapman WC, Wright JK, et al. Surgical experience with hepatic colorectal metastasis. Am Surg 1999; 65(6):560–566.

    PubMed  CAS  Google Scholar 

  15. Harmon KE, Ryan JA, Biehl TR, et al. Benefits and safety of hepatic resection for colorectal metastases. Am J Surg 1999; 177(5):402–404.

    Article  PubMed  CAS  Google Scholar 

  16. Yamamoto J, Shimada K, Kosuge T, et al. Factors influencing survival of patients undergoing hepatectomy for colorectal metastases. Br J Surg 1999;86(3):332–337.

    Article  PubMed  CAS  Google Scholar 

  17. Fong Y, Fortner J, Sun RL, et al. Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: Analysis of 1001 consecutive cases. Ann Surg 1999;230(3):309–318.

    Article  PubMed  CAS  Google Scholar 

  18. Minagawa M, Makuuchi M, Torzilli G, et al. Extension of the frontiers of the surgical indications in the treatment of liver metastases from colorectal cancer: Long-term results. Ann Surg 2000;231(4):487–499.

    Article  PubMed  CAS  Google Scholar 

  19. Adam R. Current surgical strategies for the treatment of colorectal cancer liver metastases. European J Cancer Suppl 2004;2(7):21–26.

    Article  Google Scholar 

  20. Muratore A, Polastri R, Bouzari H, et al. Repeat hepatectomy for colorectal liver metastases: a worthwhile operation? J Surg Oncol 2001;76(2):127–132.

    Article  PubMed  CAS  Google Scholar 

  21. Adam R, Pascal G, Azoulay D, et al. Liver resection for colorectal metastases: the third hepatectomy. Ann Surg 2003; 238(6):871–883.

    Article  PubMed  Google Scholar 

  22. Adam R, Delvart V, Pascal G, et al. Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: A model to predict long-term survival. Ann Surg 2004;240(4):644–657.

    PubMed  Google Scholar 

  23. Adam R. The importance of visceral metastasectomy in colorectal cancer. Ann Oncol 2000;11(Suppl 3):29–36.

    Article  PubMed  Google Scholar 

  24. Adam R, Laurent A, Azoulay D, et al. Two-stage hepatectomy: a planned strategy to treat irresectable liver tumors. Ann Surg 2000;232(6):777–785.

    Article  PubMed  CAS  Google Scholar 

  25. Adam R, Avisar E, Ariche A, et al. Five-year survival following hepatic resection after neoadjuvant therapy for nonresectable colorectal. Ann Surg Oncol 2001;8(4):347–353.

    Article  PubMed  CAS  Google Scholar 

  26. Adam R. Chemotherapy and surgery: new perspectives on the treatment of unresectable liver metastases. Ann Oncol 2003;14(Suppl 2:ii):13–16.

    Google Scholar 

  27. Adam R, Lucidi V, Bismuth H. Hepatic colorectal metastases: methods of improving resectability. Surg Clin North Am 2004;84(2):659–671.

    Article  PubMed  Google Scholar 

  28. Adam R, Pascal G, Castaing D, et al. Tumor progression while on chemotherapy: a contraindication to liver resection for multiple colorectal metastases? Ann Surg 2004; 240(6):1052–1061.

    Article  PubMed  Google Scholar 

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Correspondence to Peter Metrakos M.D..

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Horton, P.J., Chaudhury, P.K., Znajda, T.L. et al. Novel two-step resection for lesions between the middle hepatic vein and vena cava which allows the middle hepatic vein to be preserved. J Gastrointest Surg 10, 69–76 (2006). https://doi.org/10.1016/j.gassur.2005.07.023

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  • DOI: https://doi.org/10.1016/j.gassur.2005.07.023

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