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Deutsche Zeitschrift für Akupunktur

, Volume 55, Issue 4, pp 22–24 | Cite as

Acupuncture for migraine prophylaxis: a randomized controlled trial

  • Ying Li
  • Hui Zheng
  • Claudia M. Witt
  • Stephanie Roll
  • Shu-guang Yu
  • Jie Yan
  • Guo-jie Sun
  • Ling Zhao
  • Wen-jing Huang
  • Xiao-rong Chang
  • Hong-xing Zhang
  • De-jun Wang
  • Lei Lan
  • Ran Zou
  • Fan-rong Liang
  • Wolfgang Raith
Journal Club
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Abstract

Background

Acupuncture is commonly used to treat migraine. We assessed the efficacy of acupuncture at migraine-specific acupuncture points compared with other acupuncture points and sham acupuncture.

Methods

We performed a multicentre, singleblind randomized controlled trial. In total, 480 patients with migraine were randomly assigned to one of four groups (Shaoyang-specific acupuncture, Shaoyang-nonspecific acupuncture, Yangming-specific acupuncture or sham acupuncture [control]). All groups received 20 treatments, which included electrical stimulation, over a period of four weeks. The primary outcome was the number of days with a migraine experienced during weeks 5–8 after randomization. Our secondary outcomes included the frequency of migraine attack, migraine intensity and migrainespecific quality of life.

Results

Compared with patients in the control group, patients in the acupuncture groups reported fewer days with a migraine during weeks 5–8, however the differences between treatments were not significant (p > 0.05). There was a significant reduction in the number of days with a migraine during weeks 13–16 in all acupuncture groups compared with control (Shaoyang-specific acupuncture v. control: difference −1.06 [95% confidence interval (CI) −1.77 to −0.5], p = 0.003; Shaoyang-nonspecific acupuncture v. control: difference −1.22 [95% CI −1.92 to −0.52], p < 0.001; Yangming-specific acupuncture v. control: difference −0.91 [95% CI −1.61 to −0.21], p = 0.011). We found that there was a significant, but not clinically relevant, benefit for almost all secondary outcomes in the three acupuncture groups compared with the control group. We found no relevant differences between the three acupuncture groups.

Interpretation

Acupuncture tested appeared to have a clinically minor effect on migraine prophylaxis compared with sham acupuncture.

Trial Registration

Clinicaltrials.gov NCT00599586

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Literatur

  1. 1.
    Linde K, Allais G, Brinkhaus B et al. Acupuncture for migraine prophylaxis. Cochrane Database Syst Rev. 2009 Jan 21;(1):CD001218. ReviewGoogle Scholar
  2. 2.
    Jena S, Witt CM, Brinkhaus B et al. Acupuncture in patients with headache. Cephalalgia 2008;28:969–79CrossRefPubMedGoogle Scholar
  3. 3.
    Molsberger A. The role of acupuncture in the treatment of migraine. CMAJ. 2012 Mar 6;184(4):391–2. Epub 2012 Jan 9CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2012

Authors and Affiliations

  • Ying Li
    • 1
  • Hui Zheng
    • 1
  • Claudia M. Witt
    • 2
    • 3
  • Stephanie Roll
    • 2
  • Shu-guang Yu
    • 1
  • Jie Yan
    • 4
  • Guo-jie Sun
    • 5
  • Ling Zhao
    • 1
  • Wen-jing Huang
    • 1
    • 2
  • Xiao-rong Chang
    • 4
  • Hong-xing Zhang
    • 5
  • De-jun Wang
    • 1
  • Lei Lan
    • 4
  • Ran Zou
    • 5
  • Fan-rong Liang
    • 1
  • Wolfgang Raith
    • 6
  1. 1.Chengdu University of Traditional Chinese MedicineChengdu, SichuanChina
  2. 2.Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical CenterBerlinGermany
  3. 3.Center for Integrative MedicineUniversity of Maryland School of MedicineBaltimoreUSA
  4. 4.Hunan University of Traditional Chinese MedicineChangsha, HunanChina
  5. 5.Hubei University of Traditional Chinese MedicineWuhan, HubeiChina
  6. 6.Klinische Abteilung für Neonatologie, Forschungsgruppe für Traditionelle Chinesische Medizin in der Pädiatrie, TCM Center GrazUniversitätsklinik für Kinder- und Jugendheilkunde, Medizinische Universität GrazGrazÖsterreich

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