Abstract
Plants represent a huge source of substances, with pharmacological potential. Brazil has a diversity of agricultural insect pests and an urgent need for safer methods of insect control. Dysdercus peruvianus (Guerin-Meneville, 1831), Pyrrhocoridae, is an economically important species of the Order Hemiptera and a pest of cotton (Gossypium hirsutum L., Malvaceae). Secondary metabolites in stems of Clusia hilariana Schltdl., Clusiaceae, such as terpenes and benzophenones, have been reported to be insecticidal. The present study investigated the effects of semi-purified fractions of hexane crude extracts from male C. hilariana stems on development of D. peruvianus. Biological parameters at different stages of development including body malformations, range of molting period and toxicity were evaluated. Most insects died and failed to develop due to attachment of their exuviae to the abdomen. Deformations of wings and defective tarsi also occurred. The secondary metabolites from semi-purified fractions of C. hilariana caused mortality, interference in molting and metamorphosis, and body deformations, probably by interacting with the neuroendocrine system. The results demonstrate the potential of C. hilariana extracts as an alternative for the control of the phytophagous insect D. peruvianus and for the development of environmentally safe and biodegradable bio insecticides.
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Alencar, J., Gil-Santana, H.R., Mello, C.F., Marcondes, C.B., Mallet, J.R.S., 2019. Ultra-structure and morphometry of the egg of Coquillettidia albifera (Prado) with illustrations of male genitalia (Diptera: culicidae). Zootaxa (online), 4565, https://doi.org/10.11646/zootaxa.4565.1.13.
Anholeti, M.C., Duprat, R.C., Figueiredo, M.R., Kaplan, M.A.C., Santos, M.G., Gonzalez, M.S., Ratcliffe, N.A., Feder, D., Paiva, S.R., Mello, C.B., 2015. Biocontrol evaluation of extracts and a major component, clusianone, from Clusia fluminensis Planch & Triana against Aedes aegypti. Mem. Inst. Oswaldo Cruz 110, 629–635.
Duprat, R.C., Anholeti, M.C., Souza, B.P., Pacheco, J.P.F., Figueiredo, M.R., Kaplan, M.A.C., Santos, M.G., Gonzalez, M.S., Ratcliffe, N.A., Mello, C.B., Paiva, S.R., Feder, D., 2017. Laboratory evaluation of Clusia fluminensis extracts and their isolated compounds against Dysdercus peruvianus and Oncopeltus fasciatus. Rev. Bras. Farmacogn. 27, 59–66.
Farooqui, T., 2007. Octopamine-mediated neuromodulation of insect senses. Neurochem. Res. 32, 1511–1529.
Fernandes, C.P., Xavier, A., Pacheco, J.P.F., Santos, M.G., Mexas, R., Ratcliffe, N.A., Gonzalez, M.S., Mello, C.B., Rocha, L, Feder, D., 2013. Laboratory evaluation of the Manilkara subsericea (Mart.) Dubard extracts and triterpenes on development of Dysdercus peruvianus and Oncopeltus fasciatus. Pest Manag. Sci. 69, 292–301.
Gallo, D., 1998. Manual de entomologia agrícola, vol. 10., 2nd ed CERES, São Paulo, Cap 2, pp. 8–9 and cap 3, pp 57.
Koul, O., Walia, S., Dhaliwal, G.S., 2008. Essential oils as green pesiticides. Biopestic. Int. 4, 63–84.
Kelecom, A., Reis, G.L., Fevereiro, P.C.A., Silva, J.G., Santos, M.G., Neto, C.B.M., Gonzalez, M.S., Gouvea, R.C.S., Almeida, G.S.S., 2002. A multidisciplinary approach to the study of the fluminense vegetation. An. Acad. Bras. Ciênc. 74, 171–181.
Klowden, M.I., 2013. Physiological Systems in Insects, third ed. Elsevier, London, UK, pp. 25–42.
Mello, C.B., Mendonça-Lopes, D., Feder, D., Uzeda, C.D., Carneiro, R.M., Rocha, M.A., Gonzalez, M.S., 2008. Laboratory evaluation of the effects of triflumuron on the development of Rhodnius prolixus nymph. Mem. Inst. Oswaldo Cruz 103, 839–842.
Nogueira, P.C.L.V., Bittrich, V., Shepherd, G.J., Lopes, A.V., Marsaioli, A.J., 2001. The ecological and taxonomic importance of flower volatiles of Clusia species (Guttiferae). Phytochemistry 56, 443–452.
Mondal, K.A.M.S.H., Parween, S., 2000. Insect growth regulators and their potential in the management of stored-product insect pests. Integ. Pest. Manag. Rev. 5, 255295.
Porto, A.L.M., Machado, S.M.F., Oliveira, C.M.A., Bittrich, V., Amaral, M.C.E., Marsaioli, A.J., 2000. Polyisoprenylated benzophenones from Clusia floral resins. Phytochemistry 55, 755–759.
Scalerandi, E., Flores, G.A., Palacio, M., Defago, M.T., Carpinella, M.C., Valladares, G., Bertoni, A., Palacios, S.M., 2018. Undesrtanding synesgistic toxicity ofterpenes as insecticides: contribution of metabolic detoxification is Musca domestica. Front. Plant Sci. 9, https://doi.org/10.3389/fpls.2018.01579.
Silva, J.D.E.S., Flores, M.X., 1993. Strategic management of agricultural research: the EMBRAPA experience. Public Adm. Dev. 13, 249–259.
Staal, G.B., 1975. Insect growth regulators with juvenile hormone activity. Annu. Rev. Entomol. 20, 417–460.
Stevens, P.F. (2001 onwards). Angiosperm Phylogeny Website. Version 14, July 2017 [and more or less continuously updated since].ẅill do. http://www.mobot.org/MOBOT/research/APweb/.
War, A.R., Paulraj, M.G., Ahmad, T., Buhroo, A.A., Hussain, B., Ignacimuthu, S., Sharma, H.C., 2012. Mechanisms of plant defense against insects herbivores. Plant Sign. Behav. 7, 1306–1311.
Weiss, B., Amler, S., Amler, R.W., 2004. Pesticides. In: Keith, O.Y. (Ed.), Pediatric Neuropsychology. Guilford Press, New York, pp. 1030–1036.
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HCR undertook the biological tests and ran laboratory studies with semi-purified fractions; MCA and SRP analyzed chemical data from plant material; MGS collected plant material and performed taxonomic identification; SRP and DF planned experiments; HCR, MCA, SRP and DF drafted the manuscript and interpreted data; MRF interpreted data; MCA, SRP and DF supervised laboratory work; HCR undertook statistical analysis and shoot scientific photography; CBM and MSG helped with the manuscript critical reading, and JRSM helped with Scanning Electron Microscopy. All the authors have read the final manuscript and approved the submission.
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Rosado, H.C., Anholeti, M.C., Santos, M.G. et al. Effects of semi-purified fractions from stems of Clusia hilariana on the development of Dysdercus peruvianus. Rev. Bras. Farmacogn. 29, 801–806 (2019). https://doi.org/10.1016/j.bjp.2019.07.005
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DOI: https://doi.org/10.1016/j.bjp.2019.07.005