Abstract
The Brazilian flora is very rich in medicinal plants, and much information about the traditional use of the Brazilian plants is only available from early literature and we are facing a rapid process of loss of biodiversity. To retrieve data about useful plants registered in the books of the Polish physicist P.L.N. Chernoviz, who lived in Brazil for 15 years in the 19th century. The aim is to improve our knowledge about Brazilian plants, and to ensure the benefits of sharing it with potential users. Data about Brazilian plants were obtained from six editions of the book Formulary and Medical Guide (Formulário e Guia Médico), published in 1864, 1874, 1888, 1892, 1897 and 1920. All this information was then organized in boxes, and correlated with pharmacological studies from PubMed and Lilacs. A total of 238 species were recorded and 117 different traditional uses were registered for the plants. The most common uses were to treat general skin diseases and intermittent fevers, as purgative, diuretics and andidiarrheal. From the total, only 61 species (25.6%) have been to date subject to pharmacological studies and had their activities confirmed. Chernoviz books represent an important source of data about plants used in traditional medicine of Brazil. Their records were collected at a time when Brazil’s native vegetation was still largely intact, and traditional medicine was practiced based on native plants. We argue that these plants must be prioritized in development of medicines, submitting them to clinical studies or by considering their traditionality, as established by WHO. Strategies for the protection of the traditional knowledge are also necessary.
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Ademola, I.O., Fagbemi, B.O., Idowu, S.O., 2007. Anthelmintic activity of Spigelia anthelmia extract against gastrointestinal nematodes of sheep. Parasitol. Res. 101, 63–69.
Adetutu, A., Morgan, W.A., Corcoran, O., Chimezie, F., 2012. Antibacterial activity and in vitro cytotoxicity of extracts and fractions of Parkia biglobosa (jacq.) Benth. stem bark and Ageratum conyzoides Linn, leaves. Environ. Toxicol. Pharmacol. 34, 478–483.
Agra, I.K., Pires, L.L., Carvalho, O.S., Silva-Filho, E.A., Smaniotto, S., Barreto, E., 2013. Evaluation of wound healing and antimicrobial properties of aqueous extract from Bowdichia virgilioides stem barks in mice. An. Acad. Bras. Cienc. 85, 945–954.
Andrade-Neto, V.F., Brandão, M.G., Stehmann, J.R., Oliveira, L.A., Krettli, A.U., 2003. Antimalarial activity of Cinchona-like plants used to treat fever and malaria in Brazil. J. Ethnopharmacol. 87, 253–256.
Annan, It, Houghton, P.J., 2008. Antibacterial, antioxidant and fibroblast growth stimulation of aqueous extracts of Ficus asperifolia Miq. and Gossypium arboreum L., wound-healing plants of Ghana. J. Ethnopharmacol. 119, 141–144.
Araujo, A.A., Soares, L.A., Assunção Ferreira, M.R., Souza Neto, M.A., Silva, G.R., Araújo Jr., R.F., Guerra, G.C., Melo, M.C., 2014. Quantification of polyphenols and evaluation of antimicrobial, analgesic and anti-inflammatory activities of aqueous and acetone-water extracts of Libidibia ferrea, Parapiptadenia rigida and Psidium guajava. J. Ethnopharmacol. 156, 88–96.
Atanasov, A.G., Waltenberger, B., Pferschy-Wenzig, E.M., Linder, T., Wawrosch, C., Uhrin, P., Temml, V., Wang, L., Schwaiger, S., Heiss, E.H., Rollinger, J.M., Schuster, D., Breuss, J.M., Bochkov, V., Mihovilovic, M.D., Kopp, B., Bauer, R., Dirsch, V.M., Stuppner, H., 2015. Discovery and resupply of pharmacologically active plant-derived natural product: a review. Biotechnol. Adv. 33, 1582–1614.
Avila-Blanco, M.E., Rodríguez, M.G., Moreno, D.J.L., Muñoz-Ortega, M., Ventura-Juárez, J., 2014. Amoebicidal activity of essential oil of Dysphania ambrosioides (L.) Mosyakin & Clemants in an amoebic liverabscess hamster model. Evid. Based Complement. Alternat. Med., https://doi.org/10.1155/2014/930208.
Badilla, B., Mora, G., Poveda, L.J., 1999. Anti-inflammatory activity of aqueous extracts of five Costa Rican medicinal plants in Sprague-Dawley rats. Rev. Biol. Trop. 47, 723–727.
Barros, W.M., Rao, V.S., Silva, R.M., Lima, J.C., Martins, D.T., 2010. Anti-inflammatory effect of the ethanolic extract from Bowdichia virgilioides H.B.K. stem bark. An. Acad. Bras. Cienc. 82, 609–616.
Bastos, G.N., Santos, A.R., Ferreira, V.M., Costa, A.M., Bispo, C.L., Silveira, A.J., Nascimento, J.L., 2006. Antinociceptive effect of the aqueous extract obtained from roots of Physalis anguiata L. on mice. J. Ethnopharmacol. 103, 241–245.
Birdi, T.J., Daswani, P., Brijesh, S., Tetali, P., Natu, A., Antia, N., 2010. Newer insights into the mechanism of action of Psidium guajava L. leaves in infectious diarrhoea. BMC Complement. Altera Med., https://doi.org/10.1186/1472-6882-10-33.
Birdi, T.J., Brijesh, S., Daswani, P.G., 2014. Bactericidal effect of selected antidiarrhoeal medicinal plants on intracellular heat-stable enterotoxin-producing Escherichia coli. Indian J. Pharm. Sci. 76, 229–235.
Brandao, M.G.L., Zanetti, N.N., Oliveira, P., Grael, C.F., Santos, A.C., Monte-Mor, R.L., 2008. Brazilian medicinal plants described by 19th century European naturalists and in the Official Pharmacopoeia. J. Ethnopharmacol. 120, 141–148.
Brandao, M.G.L., Cosenza, G.P., Grael, C.F.F., Netto Junior, N.L., Monte-Mór, R.L.M., 2009. Traditional uses of American plant species from the 1st edition of Brazilian Official Pharmacopoeia. Rev. Bras. Farmacogn. 19, 478–487.
Brandao, M.G.L., Pignal, M., Romaniuc, S., Grael, C.F.F., Fagg, C.W., 2012. Useful Brazilian plants listed in the held books of the French naturalist Auguste de Saint-Hilaire (1779-1853). J. Ethnopharmacol. 143, 488–500.
Breitbach, U.B., Niehues, M., Lopes, N.P., Faria, J.Q., Brandao, M.G.L., 2013. Amazonian Brazilian medicinal plants described by C.F.P. von Martius in the 19th century. J. Ethnopharmacol. 147, 180–189.
Caceres, A., Cano, O., Samayoa, B., Aguilar, L., 1990. Plants used in Guatemala for the treatment of gastrointestinal disorders. 1. Screening of 84 plants against enterobacteria. J. Ethnopharmacol. 30, 55–73.
Camporese, A., Balick, M.J., Arvigo, R., Esposito, R.G., Morsellino, N., Simone, F., Tubaro, A., 2003. Screening of anti-bacterial activity of medicinal plants from Belize (Central America). J. Ethnopharmacol. 87, 103–107.
Carlini, E.A., Oliveira, A.B., Oliveira, G.G., 1983. Psychopharmacological effects of the essential oil fraction and of the hydrolate obtained from the seeds of Licaria puchury-major. J. Ethnopharmacol. 8, 225–236.
Carvalho, L.H., Krettli, A.U., 1991. Antimalarial chemotherapy with natural products and chemically defined molecules. Mem. I. Oswaldo Cruz 86, 181–184.
Carvalho, L.H., Brandão, M.G.L., Santos-Filho, D., Lopes, J.L., Krettli, A.U., 1991. Antimalarial activity of crude extracts from Brazilian plants studied in vivo in Plasmodium berghei-infected mice and in vitro against Plasmodium falciparum in culture. Braz. J. Med. Biol. Res. 24, 1113–1123.
Castello, M.C., Phatak, A., Chandra, N., Sharon, M., 2002. Antimicrobial activity of crude extracts from plant parts and corresponding calli of Bixa orellana L. Indian J. Exp. Biol. 40, 1378–1381.
Castro, O., Barrios, M., Chinchilla, M., Guerrero, O., 1996. Biological and chemical evaluation of the effect of plant extracts on Plasmodium berghei. Rev. Biol. Trop. 44, 361–367.
Chernoviz, P.L.N., 1864. Formulário e Guia Médica, 6th ed. Em casa do Autor, Pariz.
Chernoviz, P.L.N., 1874. Formulário e Guia Médico, 9th ed. Em casa do Autor, Pariz.
Chernoviz, P.L.N., 1888. Formulário e Guia Médico, 13th ed. Livrariade A. Roger e F. Chernoviz, Pariz.
Chernoviz, P.L.N., 1892. Formulário e Guia Médico, 14th ed. Livrariade A. Roger e F. Chernoviz, Pariz.
Chernoviz, P.L.N., 1897. Formulário e Guia Médico, 16th ed. Livrariade A. Roger e F. Chernoviz, Pariz.
Chernoviz, P.L.N., 1996 [1920]. A Grande Farmacopeia Brasileira. Formulário e Guia Médico, vol. 2., 19th ed. Itatiaia, Belo Horizonte. Rio de Janeiro.
Choi, E.M., Hwang, J.K., 2003. Investigations of anti-inflammatory and antinociceptive activities of Piper cubeba, Physalis anguiata and Rosa hybrida. J. Ethnopharmacol. 89, 171–175.
Coelho, J.M., Antoniolli, A.B., Nunes e Silva, D., Carvalho, T.M., Pontes, E.R., Odashiro, A.N., 2010. Effects of silver sulfadiazine, ipê roxo (Tabebuia avellanedae) extract and barbatimão (Stryphnodendron adstringens) extract on cutaneous wound healing in rats. Rev. Col. Bras. Cir. 37, 45–51.
Cook, D., Lee, S.T., Taylor, C.M., Bassúner, B., Riet-Correa, F., Pfister, J.A., Gardner, D.R., 2014. Detection of toxic monofluoroacetate in Palicourea species. Toxicon 80, 9–16.
Cosenza, G.P., Somavilla, N.S., Fagg, C.W., Brandao, M.G.L., 2013. Bitter plants used as substitute of Cinchona spp. (quina) in Brazilian traditional medicine. J. Ethnopharmacol. 149, 790–796.
Costa, S.S., Souza, M.L., Ibrahim, T., Melo, G.O., Almeida, A.P., Guette, C., Férézou, J.P., Koatz, V.L., 2006. Kalanchosine dimalate, an anti-inflammatory salt from Kalanchoe brasiliensis. Nat. Prod. 69, 815–818.
Cravotto, G., Boffa, L., Genzini, L., Garella, D., 2010. Phytotherapeutics: an evaluation of the potential of 1000 plants. J. Clin. Pharm. Ther. 35, 11–48.
Dal Belo, C.A., Lucho, A.P., Vinadé, L., Rocha, L., Seibert Franca, H., Marangoni, S., Rodrigues-Simioni, L., 2013. In vitro antiophidian mechanisms of Hypericum brasiliense choisy standardized extract: quercetin-dependent neuroprotection. Biomed. Res. Int., https://doi.org/10.1155/2013/943520.
Dash, G.K., Murthy, P.N., 2011. Studies on wound healing activity of Heliotropium indicum Linn, leaves on rats. ISRN Pharmacol., https://doi.org/10.5402/2011/847980.
Delia Loggia, R., Tubaro, A., Redaelli, C., 1981. Evaluation of the activity on the mouse CNS of several plant extracts and a combination of them. Rev. Neurol. 51, 297–310.
Devi Ramaiya, S., Bujang, J.S., Zakaria, M.H., King, W.S., Shaffiq Sahrir, M.A., 2013. Sugars, ascorbic acid, total phenolic content and total antioxidant activity in passion fruit (Passiflora) cultivars. J. Sci. Food Agric. 93, 1198–1205.
Estevao, L.R., Mendonca, F.S., Baratella-Evêncio, L., Simöes, R.S., Barros, M.E., Arantes, R.M., Rachid, M.A., Evêncio-Neto, J., 2013. Effects of aroeira (Schinus terebinthi-folius Raddi) oil on cutaneous wound healing in rats. Acta Cir. Bras. 28, 202–209.
Fagg, C.W., Lughadha, E.N., Milliken, W., Hind, D.N., Brandão, M.G.L., 2015. Useful Brazilian plants listed in the manuscripts and publications of the Scottish medic and naturalist George Gardner(1810-1849). J. Ethnopharmacol. 161, 18–29.
Figueredo, S.M., Nascimento, F.P., Freitas, C.S., Baggio, C.H., Soldi, C., Pizzolatti, M.G., Ibarrola Mdel, C., Arrua, R.L., Santos, A.R., 2011. Antinociceptive and gastro-protective actions of ethanolic extract from Pluchea sagittalis (Lam.) Cabrera. J. Ethnopharmacol. 135, 603–609.
Fischer, D.C., Amorim Gualda, N.C., Bachiega, D., Carvalho, C.S., Lupo, F.N., Bonotto, S.V., Alves, M.O., Yogi, A., Santi, S.M., Avila, P.E., Kirchgatter, It, Moreno, P.R., 2004. In vitro screening for antiplasmodial activity of isoquinoline alkaloids from Brazilian plant species. Acta Trop. 92, 261–266.
Fleischer, T.C., Ameade, E.P., Mensah, M.X., Sawer, I.K., 2003. Antimicrobial activity of the leaves and seeds of Bixa orellana. Fitoterapia 74, 136–138.
Forzza, R.C., Baumgratz, J.F., Bicudo, C.E.M., Canhos, D.A.L.C., Anibal, A.C., Marcus, A.N., Costa, A.F.C., Hopkins, D.P., Leitman, M.G., Lohmann, L.G., Lughadha, E.N., Maia, L.C.M., Menezes, G., Morim, M., Peixoto, M.P., Pirani, A.L., Prado, J.R., Queiroz, J., Souza, L.P., Souza, S., Castro, V., Stehmann, J.R., Sylvestre, L., Walter, S., Bruno, M.T., Zappi, D.C., 2012. New Brazilian floristic list highlights conservation challenges. Bioscience 62, 39–45.
Franssen, F.F., Smeijsters, L.J., Berger, I., Medinilla Aldana, B.E., 1997. In vivo and in vitro antiplasmodial activities of some plants traditionally used in Guatemala against malaria. Antimicrob. Agents Chemother. 41, 1500–1503.
Fratianni, F., Nazzaro, F., Marandino, A., Fusco, M.R., Coppola, R., Feo, V., Martino, L., 2013. Biochemical composition, antimicrobial activities, and anti-quorum-sensing activities of ethanol and ethyl acetate extracts from Hypericum connatum Lam. (Guttiferae). J. Med. Food 16, 454–459.
Fritz, D., Venturi, C.R., Cargnin, S., Schripsema, J., Roehe, P.M., Montanha, J.A., Poser, G.L., 2007. Herpes virus inhibitory substances from Hypericum connatum Lam., a plant used in southern Brazil to treat oral lesions. J. Ethnopharmacol. 113, 517–520.
Gelmini, F., Beretta, G., Anselmi, C., Centini, M., Magni, P., Ruscica, M., Cavalchini, A., Maffei Facino, R., 2013. GC-MS profiling of the phytochemical constituents of the oleoresin from Copaifera langsdorffri Desf. and a preliminary in vivo evaluation of its antipsoriatic effect. Int. J. Pharm. 440, 170–178.
Ghosh, S., Sarma, M., Patra, A., Hazra, B., 2010. Anti-inflammatory and anticancer compounds isolated from Ventilago madraspatana Gaertn., Rubia cordifolia Linn, and Lantana camara Linn. J. Pharm. Pharmacol. 62, 1158–1166.
Giribabu, N., Rao, P.V., Kumar, K.P., Muniandy, S., Swapna Rekha, S., Salleh, N., 2014. Aqueous extract of Phyllanthus niruri leaves displays in vitro antioxidant activity and prevents the elevation of oxidative stress in the kidney of streptozotocin-induced diabetic male rats. Evid. Based Complement. Alternat. Med., https://doi.org/l0.1155/2014/834815.
Giulietti, A.M., Raymond, M.H., Queiroz, L.P., Wanderley, M.G.L., Berg, V., 2005. Biodiversity and conservation of plants in Brazil. Conserv. Biol. 19, 632–639.
Gomes, P.B., Oliveira, M.M., Nogueira, C.R., Noronha, E.C., Carneiro, L.M., Bezerra, J.N., Neto, M.A., Vasconcelos, S.M., Fonteles, M.M., Viana, G.S., Sousa, F.C., 2005. Study of antinociceptive effect of isolated fractions from Petiveria alliacea L. (tipi) in mice. Biol. Pharm. Bull. 28, 42–46.
Guenka, K., Gomes, R.C., Melo, V.L., Kitanishi, C.R., Pereira, P.S., Franca, S.C., Couto, L.B., Beleboni, R.O., 2008. Anti-inflammatory and antinociceptive effects of Zeyheria montana (Bignoniaceae) ethanol extract. Mem. I. Oswaldo Cruz 103, 768–772.
Guimaraes, M.R.C., 2005. Chernoviz e os manuais de medicina popular no Império. Hist. Cienc. Saude Man. 12, 501–514.
Gupta, M., Mazumder, U.K., Chaudhuri, I., Chaudhuri, R.K., Bose, P., Bhattacharya, S., Manikandan, L., Patra, S., 2002. Antimicrobial activity of Eupatorium ayapana. Fitoterapia 73, 168–170.
Heinrich, M., Kufer, J., Leonti, M., Pardo-de-Santayanna, M., 2006. Ethnobotany and ethnopharmacology - interdisciplinary links with the historical sciences. J. Ethnopharmacol. 107, 157–160.
Henriques, M., Penido, C., 2014. The therapeutic properties of Carapa guianensis. Curr. Pharm. Des. 20, 850–856.
Hiruma-Lima, C.A., Rodrigues, C.M., Kushima, H., Moraes, T.M., Lolis, S.F., Feitosa, S.B., Magri, L.P., Soares, F.R., Cola, M.M., Andrade, F.D., Vilegas, W., Souza Brito, A.R., 2009. The anti-ulcerogenic effects of Curatella americana L J. Ethnopharmacol. 121, 425–432.
Ibrahim, T., Cunha, J.M., Madi, K., Fonseca, L.M., Costa, S.S., Goncalves Koatz, V.L., 2002. Immunomodulatory and anti-inflammatory effects of Kalanchoe brasilien-sis. Int. Immunopharmacol. 2, 875–883.
Ishida, K., Mello, J.C., Cortez, D.A., Filho, B.P., Ueda-Nakamura, T., Nakamura, C.V., 2006. Influence of tannins from Stryphnodendron adstringens on growth and virulence factors of Candida albicans. J. Antimicrob. Chemother. 58, 942–949.
Iwamoto, L.H., Vendramini-Costa, D.B., Monteiro, P.A., Ruiz, A.L., Sousa, I.M., Foglio, M.A., Carvalho, J.E., Rodrigues, R.A., 2015. Anticancer and antiinflammatory activities of a standardized dichloromethane extract from Piper umbellatum L leaves. Evid. Based. Complement. Alternat. Med., https://doi.org/10.1155/2015/948737.
Jang, M., Jeong, S.W., Cho, S.K., Ahn, K.S., Lee, J.H., Yang, D.C., Kim, J.C., 2014. Antiinflammatory effects of an ethanolic extract of guava (Psidium guajava L) leaves in vitro and in vivo. J. Med. Food 17, 678–685.
Jegede, O.C., Ajanusi, J.O., Adaudi, A.O., Agbede, R.I., 2006. Anthelmintic efficacy of extracts of Spigelia anthelmia Linn on experimental Nippostrongylus braziliensis in rats. Jpn. J. Vet. Sci. 7, 229–232.
Kamel, E.G., El-Emam, M.A., Mahmoud, S.S., Fouda, F.M., Bayaumy, F.E., 2011. Para-sitological and biochemical parameters in Schistosoma mansoni-infected mice treated with methanol extract from the plants Chenopodium ambrosioides, Conyza dioscorides and Sesbania sesban. Parasitol. Int. 60, 388–392.
Kouam, M.K., Payne, V.K., Miégoué, E., Tendonkeng, F., Lemoufouet, J., Kana, J.R., Boukila, B., Pamo, E.T., Mnm, B., 2015. Evaluation of in vivo acaricidal effect of soap containing essential oil of Chenopodium ambrosioides leaves on Rhipicephalus lunulatus in the western highland of Cameroon. J. Pathog., https://doi.org/10.1155/2015/516869.
Kviecinski, M.R., Felipe, K.B., Correia, J.F., Ferreira, E.A., Rossi, M.H., Moura Gatti, F., Filho, D.W., Pedrosa, R.C., 2011. Brazilian Bidens pilosa Linné yields fraction containing quercetin-derived flavonoid with free radical scavenger activity and hepatoprotective effects. Libyan J. Med. 6, 1–8.
Leitao, F., Leitao, S.G., Almeida, M.Z., Cantos, J., Coelho, T., Silva, P.E., 2013. Medicinal plants from open-air markets in the State of Rio de Janeiro, Brazil as a potential source of new antimycobacterial agents. J. Ethnopharmacol. 149, 513–521.
Lopes-Martins, R.A., Pegoraro, D.H., Woisky, R., Penna, S.C., Sertié, J.A., 2002. The anti-inflammatory and analgesic effects of a crude extract of Petiveria alliacea L (Phytolaccaceae). Phytomedicine 9, 245–248.
Luiz, R.L., Vila, T.V., Mello, J.C., Nakamura, C.V., Rozental, S., Ishida, K., 2015. Proanthocyanidins polymeric tannin from Stryphnodendron adstringens are active against Candida albicans biofllms. BMC Complement. Altern. Med., https://doi.org/10.1186/s12906-015-0597-4.
Magrini, F.E., Specht, A., Gaio, J., Girelli, C.P., Migues, I., Heinzen, H., Sartori, V.C., Cesio, V., 2014. Viability of Cabralea canjerana extracts to control the South American fruit fly, Anastrepha fraterculus. J. Insect Sci., https://doi.org/10.1093/jis/14.1.47.
Maranhao, H.M., Vasconcelos, C.F., Rolim, L.A., Neto, P.J., Neto, J.C., Filho, R.C., Fernan-des, M.P., Costa-Silva, J.H., Araújo, A.V., Wanderley, A.G., 2014. Hepatoprotective effect of the aqueous extract of Simarouba amara Aublet (Simaroubaceae) stem bark against carbon tetrachloride (CCl4)-induced hepatic damage in rats. Molecules 19, 17735–17746.
Martius, C.F.P., 1843. Systema Materiae Medicae Vegetabilis Brasiliensis, Lipsiae.
Mbeunkui, F., Grace, M.H., Lategan, C., Smith, P.J., Raskin, L., Lila, M.A., 2012. In vitro antiplasmodial activity of indole alkaloids from the stem bark of Geissospermum vellosii. J. Ethnopharmacol. 139, 471–477.
Meccia, G., Quintero, P., Rojas, L.B., Usubillaga, A., Velasco, J., Diaz, T., Diaz, C., Velasquez, J., Toro, M., 2013. Chemical composition of the essential oil from the leaves of Carapa guianensis collected from Venezuelan Guayana and the antimicrobial activity of the oil and crude extracts. Nat. Prod. Commun. 8, 1641–1642.
Medeiros, M.F.T., 2008. Historical Ethnobotany: an approach through historical documents and their implications now days. In: Albuquerque, U.P., Hanzaki, N. (Eds.), Recent Development and Case Studies in Ethnobotany. Brazilian Society of Ethnobiology and Ethnoecology, Recife, pp. 127–142.
Mesia-Vela, S., Santos, M.T., Souccar, C., Lima-Landman, M.T., Lapa, A.J., 2002. Soianum paniculatum L (Jurubeba): potent inhibitor of gastric acid secretion in mice. Phytomedicine 9, 508–514.
Micali, S., Sighinolfl, M.C., Celia, A., Stefani, S., Grande, M., Cicero, A.F., Bianchi, G., 2006. Can Phyllanthus niruri affect the efficacy of extracorporeal shock wave lithotripsy for renal stones? A randomized, prospective, long-term study. J. Urol. 176, 1020–1022.
Michelin, D.C., Salgado, H.R.N., 2004. Evaluation of the laxative activity ofOperculina macrocarpa L Urban (Convolvulaceae). Rev. Bras. Farmacogn. 14, 105–109.
Miot, H.A., Batistella, R.F., Batista, K.A., Volpato, D.E., Augusto, L.S., Madeira, N.G., Haddad Jr., V., Miot, L.D., 2004. Comparative study of the topical effectiveness of the andiroba oil (Carapa guianensis) and DEET 50% as repellent for Aedes sp. Rev. I. Med. Trop. 46, 253–256.
Miranda Júnior, R.N., Dolabela, M.F., Silva, M.N., Póvoa, M.M., Maia, J.G., 2012. Antiplasmodial activity of the andiroba (Carapa guianensis Aubl., Meliaceae) oil and its limonoid-rich fraction. J. Ethnopharmacol. 142, 679–683.
Morey, A.T., Souza, F.C., Santos, J.P., Pereira, C.A., Cardoso, J.D., Almeida, R.S., Costa, M.A., Mello, J.C., Nakamura, C.V., Pinge-Filho, P., Yamauchi, L.M., Yamada-Ogatta, S.F., 2015. Antifungal activity of condensed tannins from Stryphnodendron adstringens: effect on Candida tropicalis growth and adhesion properties. Curr. Pharm. Biotechnol. 17, 365–375.
Nayak, B.S., Kanhai, J., Milne, D.M., Swanston, W.H., Mayers, S., Eversley, M., Rao, A.V., 2010. Investigation of the wound healing activity of Carapa guianensis L (Meliaceae) bark extract in rats using excision, incision, and dead space wound models. J. Med. Food 13, 1141–1146.
Nayak, B.S., Kanhai, J., Milne, D.M., Pinto Pereira, L., Swanston, W.H., 2011. Experimental evaluation of ethanolic extract of Carapa guianensis L leaf for its wound healing activity using three wound models. Evid. Based. Complement. Alternat. Med., https://doi.org/10.1093/ecam/nep160.
Neves, E.G., 2006. Arqueologia da Amazonia. Jorge Zahar Editor, Rio de Janeiro.
Nishioka, S.E.A., Escalante, R.D., 1997. Poisoning by the ingestion of seeds of the fruit of the “cotieira” (Joannesiaprinceps). Sao Paulo Med. J. 115, 1366–1367.
Nogueira, N.P., Reis, P.A., Laranja, G.A., Pinto, A.C., Aiub, C.A., Felzenszwalb, I., Paes, M.C., Bastos, F.F., Bastos, V.L., Sabino, K.C., Coelho, M.G., 2011. In vitro and in vivo toxicologicalevaluationof extract and fractions from Baccharis trimera with antiinflammatory activity. J. Ethnopharmacol. 138, 513–522.
Noldin, V.F., Oliveira Martins, D.T., Marcello, C.M., Silva Lima, J.C., Delle Monache, F., Cechinel Filho, V., 2005. Phytochemical and antiulcerogenic properties of rhizomes from Simaba ferruginea St. Hill. (Simaroubaceae). Z. Naturforsch. 60, 701–706.
Ojewole, J.A., Awe, E.O., Chiwororo, W.D., 2008. Antidiarrhoeal activity of Psidium guajava Linn. (Myrtaceae) leaf aqueous extract in rodents. J. Smooth Muscle Res. 44, 195–207.
Olajide, O.A., Aderogba, M.A., Adedapo, A.D., Makinde, J.M., 2004. Effects oiAnac-ardium occidentale stem bark extract on in vivo inflammatory models. J. Ethnopharmacol. 95, 139–142.
Oliveira Campos, M.P., Riechelmann, R., Martins, K., Hassan, B.J., Casa, F.B., Del Giglio, A., 2011. Guarana (Paullinia cupana) improves fatigue in breast cancer patients undergoing systemic chemotherapy. J. Altera Complement. Med. 17, 505–512.
Oliveira, D.R., Krettli, A.U., Aguiar, A.C., Leitao, G.G., Vieira, M.N., Martins, K.S., Leitao, S.G., 2015. Ethnopharmacological evaluation of medicinal plants used against malaria by Quilombola Communities from Oriximiná, Brazil. J. Ethnopharmacol. 173, 424–434.
Paganotte, D.M., Sannomiya, M., Rinaldo, D., Vilegas, W., Salgado, H.R.N., 2016. Oper-culina macrocarpa: chemical and intestinal motility effect in mice. Rev. Bras. Farmacogn. 26, 427–432.
Paiva, L.A., Alencar Cunha, K.M., Santos, F.A., Gramosa, N.V., Silveira, E.R., Rao, V.S., 2002. Investigation on the wound healing activity of oleo-resin from Copaifera langsdorffl in rats. Phytother. Res. 16, 737–739.
Paul, E.X., Lunardelli, A., Caberlon, E., Oliveira, C.B., Santos, R.C., Biolchi, V., Bastos, C.M., Moreira, K.B., Nunes, F.B., Gosmann, G., Oliveira, J.R., 2009. Antiinflammatory and immunomodulatory effects of Bacchans trimera aqueous extract on induced pleurisy in rats and lymphoproliferation in vitro. Inflammation 32, 419–425.
Pawar, S.P., Sathwane, P.N., Metkar, B.R., Pal, S.C., Kasture, V.S., Kasture, S.B., 2004. Anti-inflammatory and analgesic activity of Anacardium Occidentale leaf extracts. Anc. Sci. Life. 19, 169–173.
Pereira, N.A., Jaccoud, R.J.S., Mors, W.B., 1996. Triaga Brasilica: renewed interest in a seventeeth-century panacea. Toxicon 34, 511–516.
Pereira, T.B., Rocha e Silva, L.F., Amorim, R.C., Melo, M.R., Zacardi de Souza, R.C., Eberlin, M.N., Lima, E.S., Vasconcellos, M.C., Pohlit, A.M., 2014. In vitro and in vivo anti-malarial activity of limonoids isolated from the residual seed biomass from Carapa guianensis (andiroba) oil production. Malaria J. 13, 317.
Pinto, S.C., Bueno, F.G., Panizzon, G.P., Morais, G., Santos, P.V., Baesso, M.X., Leite-Mello, E.V., Mello, J.C., 2015. Stryphnodendron adstringens: clarifying wound healing in Streptozotocin-Induced diabetic rats. Planta Med. 81, 1090–1096.
Pisonis, G., 1648. Historiae Naturalis & Medicae. De Arboribus, Fruticibum & Herbis Medicinalibus, ac Alimentosfis in Brasilia. Elzevier, Amsterdam.
Raupp, I.M., Sereniki, A., Virtuoso, S., Ghislandi, C., Cavalcanti e Silva, E.X., Trebien, H.A., Miguel, O.G., Andreatini, R., 2008. Anxiolytic-like effect of chronic treatment with Erythrina velutina extract in the elevated plus-maze test. J. Ethnopharmacol. 118, 295–299.
Reddy, J.S., Rao, P.R., Reddy, M.S., 2002. Wound healing effects of Heliotropium indicum, Plumbago zeylanicum and Acaiypha indica in rats. J. Ethnopharmacol. 79, 249–251.
Reis, G.O., Vicente, C., Carvalho, F.K., Heller, M., Micke, G.A., Pizzolatti, M.G., Fröde, T.S., 2014. Croton antisyphiliticus Mart, attenuates the inflammatory response to carrageenan-induced pleurisy in mice. Inflammopharmacology 22, 115–126.
Rivera-Arce, E., Chavez-Soto, M.A., Herrera-Arellano, A., Arzate, S., Agúero, J., Feria-Romero, L.A., Cruz-Guzman, A., Lozoya, X., 2007. Therapeutic effectiveness of a Mimosa tenuiflora cortex extract in venous leg ulceration treatment. J. Ethnopharmacol. 109, 523–528.
Rocha e Silva, L.F., Nogueira, K.L., Pinto, A.C., Katzin, A.M., Sussmann, R.A., Muniz, M.P., Andrade Neto, V.F., Chaves, F.C., Coutinho, J.P., Lima, E.S., Krettli, A.U., Tadei, W.P., Pohlit, A.M., 2015. In vivo antimalarial activity and mechanisms of action of 4-nerolidylcatechol derivatives. Antimicrob. Agents Chemother. 59, 3271–3280.
Roersch, C.M., 2010. Piper umbellatum L.: a comparative cross-cultural analysis of its medicinal uses and an ethnopharmacological evaluation. J. Ethnopharmacol. 131, 522–537.
Santos, A.O., Ueda-Nakamura, T., Dias Filho, B.P., Veiga Junior, V.F., Pinto, A.C., Nakamura, C.V., 2008. Antimicrobial activity of Brazilian copaiba oils obtained from different species of the Copaifera genus. Mem. I. Oswaldo Cruz 103, 277–281.
Santos, O.J., Malafaia, O., Ribas-Filho, J.M., Czeczko, N.G., Santos, R.H., Santos, R.A., 2013. Influence of Schinus terebinthifolius Raddi (aroeira) and Carapa guianensis Aublet (andiroba) in the healing process of gastrorraphies. Arq. Bras. Cir. Dig. 26, 84–91.
Santos, J.L., Dantas, R.E., Lima, C.A., Araújo, S.S., Almeida, E.C., Marcal, A.C., Estevam, C.S., 2014. Protective effect of a hydroethanolic extract from Bowdichia virgilioides on muscular damage and oxidative stress caused by strenuous resistance training in rats. J. Int. Soc. Sports Nutr. 11, 58.
Santos, E.C., Bicca, M.A., Blum-Silva, C.H., Costa, A.P., Dos Santos, A.A., Schenkel, E.P., Farina, M., Reginatto, F.H., de Lima, T.C., 2015. Anxiolytic-like, stimulant and neuroprotective effects of Ilexparaguariensis extracts in mice. Neuroscience 292, 13–21.
Santos Rosa, D., Faggion, S.A., Gavin, A.S., Anderson de Souza, M., Fachim, H.A., Ferreira dos Santos, W., Soares Pereira, A.M., Cunha, A.O., Beleboni, R.O., 2012. Erysothrine, an alkaloid extracted from flowers of Erythrina mulungu Mart, ex Benth: evaluating its anticonvulsant and anxiolytic potential. Epilepsy Behav. 23, 205–212.
Sarria, A.L., Soares, M.S., Matos, A.P., Fernandes, J.B., Vieira, P.C., Silva, M.F., 2011. Effect of triterpenoids and limonoids isolated from Cabralea canjerana and Carapa guianensis (Meliaceae) against Spodoptera frugiperda (J. E. Smith). Z. Naturforsch. 66, 245–250.
Seito, L.N., Ruiz, A.L., Vendramini-Costa, D., Tinti, S.V., Carvalho, J.E., Bastos, J.K., Di Stasi, L.C., 2011. Antiproliferative activity of three methoxylated flavonoids isolated from Zeyheria montana Mart. (Bignoniaceae) leaves. Phytother. Res. 25, 1447–1450.
Singh, B.R., Singh, V., Ebibeni, N., Singh, R.K., 2013. Antimicrobial and herbal drug resistance in enteric bacteria isolated from faecal droppings of common house Lizard/Gecko (Hemidactylus frenatus). Int. J. Microbiol., https://doi.org/10.1155/2013/340848.
Siskind, D., Robert, C., Crawford, S., 2014. Cestrum parqui and psychosis. Australas. Psychiatry 22, 305–306.
Sosa, S., Balick, M.J., Arvigo, R., Esposito, R.G., Pizza, C., Altinier, G., Tubaro, A., 2002. Screening of the topical anti-inflammatory activity of some Central American plants. J. Ethnopharmacol. 81, 211–215.
Souza-Almeida, E.S., Filho, V.C., Niero, R., Clasen, B.K., Balogun, S.O., Oliveira Martins, D.T., 2011. Pharmacological mechanisms underlying the anti-ulcer activity of methanol extract and canthin-6-one of Simaba ferruginea A. St-Hil. in animal models. J. Ethnopharmacol. 134, 630–636.
Souza, A.B., Martins, C.H., Souza, M.G., Furtado, N.A., Heleno, V.C., de Sousa, J.P., Rocha, E.M., Bastos, J.K., Cunha, W.R., Veneziani, R.C., Ambrósio, S.R., 2011. Antimicrobial activity of terpenoids from Copaifera langsdorffli Desf. against cariogenic bacteria. Phytother. Res. 25, 215–220.
Suzigan, M.I., Battochio, A.P., Coelho, K.L., Coelho, C.A., 2009. An acqueous extract of Bidens pilosa L protects liver from cholestatic disease: experimental study in young rats. Acta Cir. Bras. 24, 347–352.
Thomazzi, S.M., Silva, C.B., Silveira, D.C., Vasconcellos, C.L., Lira, A.F., Cambui, E.V., Estevam, C.S., Antoniolli, A.R., 2010. Antinociceptive and anti-inflammatory activities of Bowdichia virgilioides (sucupira). J. Ethnopharmacol. 127, 451–456.
Truiti, M.C., Sarragiotto, M.H., Abreu Filho, B.A., Nakamura, C.V., Dias Filho, B.P., 2003. In vitro antibacterial activity of a 7-O-beta-d-glucopyranosyl-nutanocoumarin from Chaptalia nutans (Asteraceae). Mem. I. Oswaldo Cruz 98, 283–286.
Tsai, J.C., Peng, W.H., Chiu, T.H., Lai, S.C., Lee, C.Y., 2011. Anti-inflammatory effects of Scoparia dulcis L. and betulinic acid. Am. J. Chin. Med. 39, 943–956.
Vargas, F.S., Almeida, D.O.P., Aranha, E.S., Boleti, A.P.A., Newton, P., Vasconcellos, M.C., Junior, V.F., Lima, E.S., 2015. Biological activities and cytotoxicity of diter-penes from Copaifera spp. Oleoresins. Molecules 20, 6194–6210.
Villalba, M.A., Carmo, M.I., Leite, M.N., Sousa, O.V., 2007. Atividades farmacológicas dos extratos de Zanthoxylum chiloperone (Rutaceae). Rev. Bras. Farmacogn. 17, 236–241.
Vilela, F.C., Bitencourt, A.D., Cabral, L.D., Franqui, L.S., Soncini, R., Giusti-Paiva, A., 2010. Anti-inflammatory and antipyretic effects of Sonchus. J. Ethnopharmacol. 127, 737–741.
Weniger, B., Robledo, S., Arango, G.J., Deharo, E., Aragón, R., Muñoz, V., Callapa, J., Lobstein, A., Anton, R., 2001. Antiprotozoal activities of Colombian plants. J. Ethnopharmacol. 78, 193–200.
WHO, 2002. Traditional Medicine Strategy 2002–2005. World Health Organization, Geneva.
Yamaguchi, M.U., Garcia, F.P., Cortez, D.A., Ueda-Nakamura, T., Filho, B.P., Nakamura, C.V., 2011. Antifungal effects of ellagitannin isolated from leaves of Ocotea odorifera (Lauraceae). Antonie Van Leeuwenhoek 99, 507–514.
Yong, Y.K., Zakaria, Z.A., Kadir, A.A., Somchit, M.N., Ee Cheng Lian, G., Ahmad, Z., 2013. Chemical constituents and antihistamine activity of Bixa orellana leaf extract. BMC Complement. Altera Med., https://doi.org/10.1186/1472-6882-13-32.
Zippel, J., Deters, A., Hensel, A., 2009. Arabinogalactans from Mimosa tenuiflora (Willd.) Poiret bark as active principles for wound-healing properties: specific enhancement of dermal fibroblast activity and minor influence on HaCaT kera-tinocytes. J. Ethnopharmacol. 124, 391–396.
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All authors contributed to the revision and writing of the manuscript. JPS reviewed and updated the botanical names. The results presented here are part of the PhD thesis or LMR.
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Ricardo, L.M., de Paula-Souza, J., Andrade, A. et al. Plants from the Brazilian Traditional Medicine: species from the books of the Polish physician Piotr Czerniewicz (Pedro Luiz Napoleão Chernoviz, 1812–1881). Rev. Bras. Farmacogn. 27, 388–400 (2017). https://doi.org/10.1016/j.bjp.2017.01.002
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DOI: https://doi.org/10.1016/j.bjp.2017.01.002