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Preoperative chemoradiation for resectable and locailv, advanced adenocarcinoma of the pancreas

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References

  1. Evans DB, Pisters PWT, Lee JE, et al.. Preoperative chemoradiation strategies for localized adenocarcinoma of the pancreas. J Hepatobiliary Pancreat Surg 1998;5:242–250.

    Article  PubMed  CAS  Google Scholar 

  2. Freeny PC, Traverso LW, Ryan JA. Diagnosis and staging of pancreatic adenocarcinoma with dynamic computed tomography. AmJ Surg 1993;165:600–606.

    Article  CAS  Google Scholar 

  3. Warshaw AL, Gu 2, Wittenberg J, et al.. Preoperative staging and assessment of resectability of pancreatic cancer. Arch Surg 1990;125:230–233.

    PubMed  CAS  Google Scholar 

  4. Evans DB, Lee JE, Pisters PWT. Pancreaticoduodenectomy (WhippIe operation) and total pancreatectomy for cancer. In Nyhus LM, Baker RJ, Fischer JF, eds. Mastery of Surgery. 3rd ed. Boston: Little, Brown, 1997, pp 1233–1249.

    Google Scholar 

  5. Bold RJ, Charnsangavej C, Cleary KR, et al.. Major vascular resection as part of pancreaticoduodenectomy for cancer: Radiologic, intraoperative, and pathologic analysis. J GASTROINTEST SURG 1999;3:233–243.

    Article  PubMed  CAS  Google Scholar 

  6. Leach SD, Lee JE, Chamsangavej C, et al.. Survival following pancreaticoduodenectomy with resection of the superior mesenteric-portal vein confluence for adenocarcinoma of the pancreatic head. BrJ Surg 1998;85:611–617.

    Article  CAS  Google Scholar 

  7. Staley CA, Cleary KR, Abbruzzese JL, et al.. Need for stan-dardized pathologic staging of pancreaticoduodenectomy specimens. Pancreas 1996;12:373–380.

    Article  PubMed  CAS  Google Scholar 

  8. Evans DB, Abbruzzese JL, Rich TA. Cancer of the pancreas. In DeVita VT, Hellman S, Rosenberg SA, eds. Cancer: Principles and Practice of Oncology, 5th ed. Philadelphia: JB Lippincott, 1997, pp 1054–1087.

    Google Scholar 

  9. Staley CA, Lee JE, Cleary KA, et al.. Preoperative chemoradiation, pancreaticoduodenectomy, and intraoperative radiation therapy for adenocarcinoma of the pancreatic head. AmJ Surg 1996;171:118–125.

    Article  CAS  Google Scholar 

  10. Hoffman JP, Lipsitz S, Pisansky T, et al.. Phase II trial of preoperative radiation therapy and chemotherapy for patients with localized, resectable adenocarcinoma of the pancreas: An Eastern Cooperative Oncology Group Study. J Clin Oncol 1998;16:317–323.

    PubMed  CAS  Google Scholar 

  11. Pisters PWT, Abbruzzese JL, Janjan NA, et al.. Rapid-fractionation preoperative chemoradiation, pancreaticoduodenectomy, and intraoperative radiation therapy for resectable pancreatic adenocarcinoma. J Clin Oncol 1998;16:3843–3850.

    PubMed  CAS  Google Scholar 

  12. Burris HA III, Moore MJ, Andersen J, et al.. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial. J Clin Oncol 1997;15:2403–2413.

    PubMed  CAS  Google Scholar 

  13. Wolff RA, Evans DB, Gravel DM, et al.. Phase I trial of gemcitabine (GEM) combined with radiation (XRT) for the treatment of locally advanced pancreatic adenocarcinoma [abstr]. Proc Am Sot Clin Oncol 1998;17:1091.

    Google Scholar 

  14. Gastrointestinal Tumor Study Group. A multi-institutional comparative trial of radiation therapy alone and in combination with 5-fluorouracil for locally unresectable pancreatic carcinoma. Ann Surg 1979;189:205.

    Google Scholar 

  15. Klaassen DJ, MacIntyre JM, Catton GE, et al.. Treatment of locally unresectable cancer of the stomach and pancreas: A randomized comparison of S-fluorouracil alone with radiation plus concurrent and maintenance S-fluorouracil—an Eastern Cooperative Oncology Group study. J Clin Oncol 1985;3:373–378.

    PubMed  CAS  Google Scholar 

  16. DiPetrillo T, Safran H. Paclitaxel and concurrent radiation for locally advanced pancreatic cancer [abstr]. Proc Am Sot Clin Oncol 2000;19:1152.

    Google Scholar 

  17. Epelbaum R, Rosenblatt E, Nasrallah S, et al.. A phase II study of gemcitabine (GEM) combined with radiation therapy (RT) in patients with localized, unresectable pancreatic cancer [abstr]. Proc Am Sot Clin Oncol 2000;19:1029.

    Google Scholar 

  18. White R, Lee C, Anscher M, et al.. Preoperative chemoradiation for patients with locally advanced adenocarcinoma of the pancreas. Arm Surg Oncol 1999;6:38–45.

    Article  Google Scholar 

  19. Blackstock AW, Bernard SA, Richards F, et al.. Phase I trial of twice-weekly gemcitabine and concurrent radiation in patients with advanced pancreatic cancer. J Clin Oncol 1999;17:2208–2212.

    PubMed  CAS  Google Scholar 

  20. Bajetta E, DiBartolomeo M, Stani SC, et al.. Chemoradiotherapy as preoperative treatment in locally advanced unresectable pancreatic cancer patients: Results of a feasibility study. Int J Radiat Oncol Biol Phys 1999;45:285–289.

    Article  PubMed  CAS  Google Scholar 

  21. Todd KE, Gloor B, Lane JS, Isacoff WH, Reber HA. Resection of locally advanced pancreatic cancer after dowustaging with continuous-infusion 5-fluorouracil, mitomycin-C, leucovorin, and dipyridamole. J GASTROINTEST Surg 1998;2:159–166.

    Article  PubMed  CAS  Google Scholar 

  22. Kamthan AG, Morris JC, Dalton J, et al.. Combined modality therapy for stage II and stage III pancreatic carcinoma. J Clin Oncol 1997;15:2920–2927.

    PubMed  CAS  Google Scholar 

  23. Safran H, Ring T, Choy H, et al.. Paclitaxel and concurrent radiation for locally advanced pancreatic and gastric cancer: A phase I study. J Clin Oncol 1997;15:901–907.

    PubMed  CAS  Google Scholar 

  24. Jessup JM, Steele G, Mayer RJ, et al.. Neoadjuvant therapy for unresectable pancreatic adenocarcinoma. Arch Surg 1993;128:559–564.

    PubMed  CAS  Google Scholar 

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Correspondence to Douglas B. Evans M.D..

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Evans, D.B. Preoperative chemoradiation for resectable and locailv, advanced adenocarcinoma of the pancreas. J Gastrointest Surg 5, 2–5 (2001). https://doi.org/10.1016/S1091-255X(01)80002-0

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