Abstract
An efficient methodology has been designed to facilitate the elucidation of chemical structures of compounds synthesized by chemists engaged in silicone research—specifically as it pertains to the analyses of mixtures of organofunctionalized Si-containing compounds. By combining electrospray MS data, IR/NMR functional group data and Diophantine mathematical analysis, one can obtain a materials balance of a particular chemical reaction without requiring difficult/time-consuming separations. This approach has been applied successfully to the analysis of F-endblocked polydiphenylsiloxanes up to 3000 Da and can be readily tailored for the structural elucidation of any organic compound.
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Frevel, L.K., Lee, WL. & Tecklenburg, R.E. Diophantine mass spectrometric structure analysis. J Am Soc Mass Spectrom 10, 231–240 (1999). https://doi.org/10.1016/S1044-0305(98)00139-1
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DOI: https://doi.org/10.1016/S1044-0305(98)00139-1