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Pressure limited sustained off-resonance irradiation for collision-activated dissociation in Fourier transform mass spectrometry

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Journal of the American Society for Mass Spectrometry

Abstract

A theoretical evaluation of the sustained off-resonance irradiation of ions (SORI) in the presence of a collisional buffer gas in a Fourier transform ion cyclotron resonance mass spectrometer is presented. It is shown that there is an optimal pressure for a given set of irradiation parameters corresponding to the most effective dissociation. Theoretical predictions are compared with experimental results for the dissociation of electrosprayed biopolymer ions and with previously accepted view of the SORI process.

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Authors and Affiliations

  1. Environmental Molecular Science Laboratory, Pacific Northwest National Laboratory, Richland, Washington, USA

    Michael V. Gorshkov, Ljiljana Pasa-Tolic & Richard D. Smith

Authors
  1. Michael V. Gorshkov
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  2. Ljiljana Pasa-Tolic
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  3. Richard D. Smith
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Correspondence to Richard D. Smith.

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Gorshkov, M.V., Pasa-Tolic, L. & Smith, R.D. Pressure limited sustained off-resonance irradiation for collision-activated dissociation in Fourier transform mass spectrometry. J Am Soc Mass Spectrom 10, 15–18 (1999). https://doi.org/10.1016/S1044-0305(98)00119-6

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  • DOI: https://doi.org/10.1016/S1044-0305(98)00119-6

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