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Matrix-assisted filament desorption/ionization mass spectrometry

  • Short Communication
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Journal of the American Society for Mass Spectrometry

Abstract

We describe an improved sample preparation method for pulsed filament desorption–ionization mass spectrometry. Samples were deposited in the presence of an excess of liquid or solid matrices. Especially with liquid matrices such as glycerol, this allowed stable and reproducible ion production for a variety of compounds, including biomolecules and synthetic polymers. Substances with molecular weights up to 3000 Da could be desorbed, ionized, and detected by time-of-flight mass spectrometry.

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Authors and Affiliations

  1. Laboratorium für Organische Chemie, Swiss Federal Institute of Technology(ETH), CH-8092, Zürich, Switzerland

    Volker Karbach, Richard Knochenmuss & Renato Zenobi

Authors
  1. Volker Karbach
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  2. Richard Knochenmuss
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  3. Renato Zenobi
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Correspondence to Renato Zenobi.

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Karbach, V., Knochenmuss, R. & Zenobi, R. Matrix-assisted filament desorption/ionization mass spectrometry. J Am Soc Mass Spectrom 9, 1226–1228 (1998). https://doi.org/10.1016/S1044-0305(98)00099-3

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  • DOI: https://doi.org/10.1016/S1044-0305(98)00099-3

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