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A gated trapping strategy with a two-time constant and a delay for catching in-field generated ions that range over three decades in mass-to-charge and two decades in velocity in Fourier-transform mass spectrometry

  • Focus: FT-ICR-MS
  • Published:
Journal of the American Society for Mass Spectrometry

Abstract

In-field, matrix-assisted laser desorption/ionization (MALDI) may provide a means to keep part of the original promise of Fourier-transform mass spectrometry (FTMS) to give high performance and versatile mass spectrometry from a mechanically simple instrument. Gated trapping has been employed as a means of catching MALDI-produced ions in the FTMS trap. This approach is important for both in-field and externally produced ions. Even with improvements, gated trapping has not yet been able to catch ions over wide ranges of mass-to-charge and velocity. A design of a “two-time constant with a delay” gated trapping strategy using “idealized” potentials in a normalized system is given as an example to establish that in principle gated trapping strategies can capture ions that range over three decades of m/z and two decades in velocity. A procedure for calculating a physical system from the normalized system is given. The design is tolerant of variations in the physical parameters used to define the physical system from the normalized system.

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  1. Department of Chemistry, Washington University, St. Louis, Missouri, USA

    D. L. Rempel & M. L. Gross

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  1. D. L. Rempel
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  2. M. L. Gross
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Rempel, D.L., Gross, M.L. A gated trapping strategy with a two-time constant and a delay for catching in-field generated ions that range over three decades in mass-to-charge and two decades in velocity in Fourier-transform mass spectrometry. J Am Soc Mass Spectrom 12, 296–303 (2001). https://doi.org/10.1016/S1044-0305(00)00225-7

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  • DOI: https://doi.org/10.1016/S1044-0305(00)00225-7

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