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Detection of femtomole and sub-femtomole levels of peptides by tandem magnetic sector/reflectron time-of-flight mass spectrometry and matrix-assisted laser desorption ionization

  • F. H. Strobel
  • T. Solouki
  • M. A. White
  • D. H. Russell
Article

Abstract

This article describes results of low-level (sub-femtomole) detection of peptides by matrix-assisted laser desorption ionization. The matrix-assisted laser desorption ionization method can be used for low-level detection of the parent ion, either [M + H]+ or [M + Na]+, and collision-induced dissociation of the parent ion can be performed at the picomole level. The instrument used for these studies is a novel high-performance magnetic sector (electric(E)/magnetic(B) sector)/reflectron time-of-flight (TOP) tandem mass spectrometer (EB/TOF).

Keywords

Laser Shot Sinapic Acid Tandem Mass Spectrometer Arrival Time Distribution Deceleration Lens 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© American Society for Mass Spectrometry 1991

Authors and Affiliations

  • F. H. Strobel
    • 1
  • T. Solouki
    • 1
  • M. A. White
    • 1
  • D. H. Russell
    • 1
  1. 1.Department of ChemistryTexas A & M UniversityCollege StationUSA

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