Neurotherapeutics

, Volume 5, Issue 1, pp 37–49 | Cite as

Motor cortex stimulation for pain and movement disorders

Review Article

Summary

Since initial reports in the early 1990s, stimulation of the Ml region of the cortex (MCS) has been used to treat chronic refractory pain conditions and a variety of movement disorders. A Medline search of literature between 1991 and 2007 revealed 512 cases using MCS. Although most of these relate to the treatment of pain (422), 84 of them involve movement disorders. More recently, several studies have specifically looked at treating Parkinson’s disease (PD) with MCS. We report here several of our own cases using MCS to treat post-stroke and non-poststroke pain syndromes and movement disorders (n = 8), PD (n = 4), ET (n = 2), and cortico-basal degeneration (n = 1). We also cover the essential history of this procedure and our current research using computational modeling to understand further the underlying mechanisms of MCS.

Key Words

Motor cortex cortical stimulation deep brain stimulation chronic pain Parkinson’s disease 

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Copyright information

© Springer New York 2008

Authors and Affiliations

  1. 1.Department of NeurosurgeryLahey ClinicBurlington
  2. 2.Department of NeurosurgeryTufts University School of MedicineBoston

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