Neurotherapeutics

, Volume 4, Issue 1, pp 126–129

Talampanel

Article

DOI: 10.1016/j.nurt.2006.11.001

Cite this article as:
Howes, J.F. & Bell, C. Neurotherapeutics (2007) 4: 126. doi:10.1016/j.nurt.2006.11.001
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Summary

Talampanel is a novel anticonvulsant that acts as an allosteric inhibitor of the AMPA receptor. Talampanel has a broad spectrum of action in animal models of epilepsy and neuroprotection. Clinical experience to date has been able to show effectiveness in reduction of seizures in patients with refractory partial seizures.

Key Words

AMPA epilepsy glutamate neuroprotection talampanel 

Copyright information

© The American Society for Experimental NeuroTherapeutics, Inc. 2007

Authors and Affiliations

  1. 1.Department of New Drug DevelopmentIVAX Research, Inc.Miami
  2. 2.Department of Oncology & CNSIVAX Research, Inc.Miami

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