Attenuation artifact, attenuation correction, and the future of myocardial perfusion SPECT

  • Bhupinder Singh
  • Timothy M. Bateman
  • James A. Case
  • Gary Heller
Editorial Point of View
This is a preview of subscription content, log in to check access.

References

  1. 1.
    Picano E, Bedetti G, Varga A, Cseh E. The comparable diagnostic accuracies of dobutamine-stress and dipyridamole-stress echocar-diographies: a meta-analysis. Coron Artery Dis 2000;11:151–9.PubMedCrossRefGoogle Scholar
  2. 2.
    Kim C, Kwok YS, Heagerty P, Redberg R. Pharmacologic stress testing for coronary disease diagnosis a meta-analysis. Am Heart J 2001;142:934–44.PubMedCrossRefGoogle Scholar
  3. 3.
    Fleischmann KE, Hunink MG, Kuntz KM, Douglas PS. Exercise echocardiography or exercise SPECT imaging? A meta-analysis of diagnostic test performance. JAMA 1998;280:913–20.PubMedCrossRefGoogle Scholar
  4. 4.
    Germano G, Slomka PJ, Berman DS. Attenuation correction in cardiac SPECT: the boy who cried wolf? J Nucl Cardiol 2007;14: 25–35.PubMedCrossRefGoogle Scholar
  5. 5.
    Johnstone D, Wackers F, Berger H, et al. Effect of patient positioning on left lateral thallium-201 myocardial images. J Nucl Med 1979;20:183–5.Google Scholar
  6. 6.
    Hansen CL, Woodhouse S, Kramer M. Effect of patient obesity on the accuracy of thallium-201 myocardial perfusion imaging. Am J Cardiol 2000;85:749–52.PubMedCrossRefGoogle Scholar
  7. 7.
    Wackers F. Diagnostic pitfalls of myocardial perfusion imaging in women. J Myocard Ischemia 1992;4:23.Google Scholar
  8. 8.
    Manglos SH, Thomas FD, Gagne GM, Hellwig BJ. Phantom study of breast tissue attenuation in myocardial imaging. J Nucl Med 1993;34:992–6.PubMedGoogle Scholar
  9. 9.
    Germano G, Chua T, Kiat H, Areeda JS, Berman DS. A quantitative phantom analysis of artifacts due to hepatic activity in technetium-99m myocardial perfusion SPECT studies. J Nucl Med 1994;35:356–9.PubMedGoogle Scholar
  10. 10.
    Nuyts J, Dupont P, Van den Maegdenbergh V, Vleugels S, Suetens P, Mortelmans L. A study of the liver-heart artifact in emission tomography. J Nucl Med 1995;36:133–9.PubMedGoogle Scholar
  11. 11.
    Holly TA, Satran A, Bromet DS, et al. The impact of adjunctive adenosine infusion during exercise myocardial perfusion imaging: results of the Both Exercise and Adenosine Stress Test (BEAST) trial. J Nucl Cardiol 2003;10:291–6.PubMedCrossRefGoogle Scholar
  12. 12.
    Pennell DJ, Mavrogeni, SI, Forbat SM, Karwatowski SP, Underwood SR. Adenosine combined with dynamic exercise for myocardial perfusion imaging. J Am Coll Cardiol 1995;25:1300–9.PubMedCrossRefGoogle Scholar
  13. 13.
    Segall GM, Davis MJ, Prone versus supine thallium myocardial SPECT: a method to decrease artifactual inferior wall defects. J Nucl Med 1989;30:548–55.PubMedGoogle Scholar
  14. 14.
    Kiat H, Van Train KF, Friedman JD, et al. Quantitative stress-redistribution thallium-201 SPECT using prone imaging: methodologic development and validation. J Nucl Med 1992;33:1509–15.PubMedGoogle Scholar
  15. 15.
    Hayes SW, De Lorenzo A, Hachamovitch R, et al. Prognostic implications of combined prone and supine acquisitions in patients with equivocal or abnormal supine myocardial perfusion SPECT J Nucl Med 2003;44:1633–40.PubMedGoogle Scholar
  16. 16.
    DePuey EG, Rozanski A. Using gated technetium-99m-sestambi SPECT to characterize fixed myocardial defects as infarct or artifact. J Nucl Med 1995;36:952–5.PubMedGoogle Scholar
  17. 17.
    Taillefer R, DePuey EG, Udelson JE, Beller GA, Benjamin C, Gagnon A, Comparison between the end-diastolic images and the summed images of gated 99mTc-sestamibi SPECT perfusion study in detection of coronary artery disease in women. J Nucl Cardiol 1999;6:169–76.PubMedCrossRefGoogle Scholar
  18. 18.
    Taillefer R, DePuey EG, Udelson JE, Beller GA, Latour Y, Reeves P. Comparative diagnostic accuracy of TI-201 and Tc-99m sestamibi SPECT imaging (perfusion and ECG-gated SPECT) in detecting coronary artery disease in women J Am Coll Cardiol 1997;29:69–77.PubMedCrossRefGoogle Scholar
  19. 19.
    Smanio PE, Watson DD, Segalla DL, et al. Value of gating of technetium-99m sestamibi single-photon emission computed fomographic imaging. Effect of attenuation correction on myocardial thallium-201 distribution in patients with a low likelihood of coronary artety disease. J. Am Coll Cardiol 1997;30:1687–92.PubMedCrossRefGoogle Scholar
  20. 20.
    Travin MI, Heller GV, Johnson LL, et al. The prognostic value of ECG-gated SPECT imaging in patients undergoing stress Tc-99m sestamibi myocardial perfusion imaging. J Nucl Cardiol 2004;11:253–62.PubMedCrossRefGoogle Scholar
  21. 21.
    Zaidi H, Hasegawa B. Determination of the attenuation map in emission tomography. J Nucl Med 2003;44:291–315.PubMedGoogle Scholar
  22. 22.
    Miles J, Cullom SJ, Case JA. An introduction to attenuation correction. J Nucl Cardiol 1999;6:449–57.PubMedCrossRefGoogle Scholar
  23. 23.
    O’Connor MK, Kemp B. Anstett F, et al. A multicenter evaluation of commercial attenuation compensation techniques in cardiac SPECT using phantom models J Nucl Cardiol 2002;9:361–76.PubMedCrossRefGoogle Scholar
  24. 24.
    King MA, Tsui BM, Pan TS. Attenuation compensation for cardiac single-photon emission computed tomographic imaging: part 1. Impact of attenuation and methods of estimating attenuation maps. J Nucl Cardiol 1995;2:513–24.PubMedCrossRefGoogle Scholar
  25. 25.
    King MA, Tsui BM, Pan TS, Glick SJ, Soares EJ. Attenuation compensation for cardiac single-photon emission computed tomographic imaging: part 2. Attenuation compensation algorithms. J Nucl Cardiol 1996;3:55–64.PubMedCrossRefGoogle Scholar
  26. 26.
    Bokulic T, Vastenhouw B, de Jong HW, van Rijk PP, Beekman FJ. Monte Carlo-based down-scatter correction of SPECT attenuation maps Eur J Nucl Med Mol Imaging 2004;31:1173–81.PubMedCrossRefGoogle Scholar
  27. 27.
    Tan P, Bailey DL, Meikle SR, Eberl S, Fulton RR, Hutton BF. A scanning line source for simultaneous emission and transmission measurements in SPECT. J Nucl Med 1993;34:1752–60.PubMedGoogle Scholar
  28. 28.
    Fleming JS. A technique for using CT images in attenuation correction and quantification in SPECT. Nucl Med Commun 1989;10:83–97.PubMedCrossRefGoogle Scholar
  29. 29.
    Takahashi Y, Murase K, Higashino H, Mochizuki T, Motomura N. Attenuation correction of myocardial SPECT images with X-ray CT: effects of registration errors between X-ray CT and SPECT. Ann Nucl Med 2002;16:431–5.PubMedCrossRefGoogle Scholar
  30. 30.
    Tonge CM, Manoharan M, Lawson RS, Shields RA, Prescott MC. Attenuation correction of myocardial SPECT studies using low resolution computed tomography images. Nucl Med Commun 2005;26:231–7.PubMedCrossRefGoogle Scholar
  31. 31.
    Kashiwagi T, Yutani K, Fukuchi M, et al. Correction of nonuniform attenuation and image fusion in SPECT imaging by means of separate X-ray CT. Ann Nucl Med 2002;16:255–61.PubMedCrossRefGoogle Scholar
  32. 32.
    Chen J, Caputlu-Wilson SF, Shi H, Galt JR, Faber TL, Garcia EV. Automated quality control of emission-transmission misalignment for attenuation correction in myocardial perfusion imaging with SPECT-CT systems. J Nucl Cardiol 2006;13:43–9.PubMedCrossRefGoogle Scholar
  33. 33.
    Goetze S, Zhang Z, Bengel FM. SPECT/CT misregistration in attenuation corrected myocardial perfusion studies [abstract]. J Nucl Cardiol 2006;13:S8.CrossRefGoogle Scholar
  34. 34.
    Utsunomiya D, Nakaura T, Honda T, et al. Object-specific attenuation correction at SPECT/CT in thorax: optimization of respiratory protocol for image registration. Radiology 2005;237:662–9.PubMedCrossRefGoogle Scholar
  35. 35.
    LaCroix K, Tsui B, Hasegawa B, Brown J, Investigation of the use of x-ray CT images for attenuation compensation in SPECT. IEEE Trans Nucl Sci 1994;41:2793–9.CrossRefGoogle Scholar
  36. 36.
    Ficaro EP, Fessler JA, Shreve PD, Kritzman JN, Rose PA, Corbett JR. Simultaneous transmission/emission myocardial perfusion tomography. Diagnostic accuracy of attenuation-corrected 99m Tc-sestamibi single-photon emission computed tomography. Circulation 1996;93:463–73.PubMedGoogle Scholar
  37. 37.
    Kluge R, Sattler B, Seese A, Knapp WH. Attenuation correction by Simultaneous emission-transmission myocardial single-photon emission tomography using a technetium-99m-labelled radiotracer impact on diagnostic accuracy. Eur J Nucl Med 1997;24:1107–14.PubMedGoogle Scholar
  38. 38.
    Gallowitsch HJ, Sykora J, Mikosch P, et al. Attenuation-corrected thallium-201 single-photon emission tomography using a gadolinium-153 moving line source: clinical value and the impact of attenuation correction on the extent and severity of perfusion abnormalities. Eur J. Nucl Med 1998;25:220–8.PubMedCrossRefGoogle Scholar
  39. 39.
    Hendel RC, Berman DS, Collom SJ, et al. Multicenter clinical trial to evaluate the efficacy of correction for photon attenuation and scatter in SPECT myocardial perfusion imaging. Circulation 1999; 99:2742–9.PubMedGoogle Scholar
  40. 40.
    Links JM, DePuey EG, Taillefer R, Becker LC. Attenuation correction and gating synergistically improve the diagnostic accuracy of myocardial perfusion SPECT. J Nucl Cardiol 2002;9:183–7.PubMedCrossRefGoogle Scholar
  41. 41.
    Hendel RC, Corbett JR, Collom SJ, DePuey EG, Garcia EV, Bateman TM, The value and practice of attenuation correction for myocardial perfusion SPECT imaging: a joint position statement from the American Society of Nuclear Cardiology and the Society of Nuclear Medicine. J Nucl Cardiol 2002;9:135–43.PubMedCrossRefGoogle Scholar
  42. 42.
    Thompson RC, Heller GV, Johnson LL, et al. Value of attenuation correction on ECG-gated SPECT myocardial perfusion imaging related to body mass index. J Nucl Cardiol 2005;12:195–202PubMedCrossRefGoogle Scholar
  43. 43.
    Grossman GB, Garcia EV, Bateman TM, et al. Quantitative Tc-99m sestamibi attenuation-corrected SPECT: development and multicenter trial validation of myocardial perfusion stress gender-independent normal database in an obese population. J Nucl Cardiol 2004;11:263–72.PubMedCrossRefGoogle Scholar
  44. 44.
    Masood Y, Liu YH, Depuey G, et al. Clinical validation of SPECT attenuation correction using x-ray computed tomography-derived attenuation maps: multicenter clinical trial with angiographic correlation. J Nucl Cardiol 2005;12:676–86.PubMedCrossRefGoogle Scholar
  45. 45.
    Fricke E, Fricke H, Weise R, et al. Attenuation correction of myocardial SPECT perfusion images with low-dose CT evaluation of the method by comparison with perfusion PET. J Nucl Med 2005;46:736–44.PubMedGoogle Scholar
  46. 46.
    Gibson PB, Demus D, Noto R, Hudson W, Johnson LL. Low event rate for stress-only perfusion imaging in patients evaluated for chest pain. J Am Coll Cardiol 2002;39:999–1004.PubMedCrossRefGoogle Scholar
  47. 47.
    Heller GV, Bateman TM, Johnson LL, et al. Clinical value of attenuation correction in stress-only Tc-99m sestamibi SPECT imaging. J Nucl Cardiol 2004;11:273–81.PubMedCrossRefGoogle Scholar
  48. 48.
    Baghdasarian SB, Mamkin I, Noble GL, Ahlberg AW, Katten DM, Heller GV, Risk stratification with attenuation corrected stress spect myocardial perfusion imaging in the absence of ECG-gating [abstract]. J Nucl Cardiol 2006;13:S36.CrossRefGoogle Scholar
  49. 49.
    Heller GV, Links J, Bateman TM, et al. American Society of Nuclear Cardiology and Society of Nuclear Medicine joint position statement: attenuation correction of myocardial perfusion SPECT seintigraphy. J Nucl Cardiol 2004;11:229–30.PubMedCrossRefGoogle Scholar
  50. 50.
    Watson DD. Is it time for SPECT attenuation correction. J Nucl Cardiol 2004;11:239–41.PubMedCrossRefGoogle Scholar
  51. 51.
    Machac J, Bacharach SL, Bateman TM, et al. Positron emission tomography myocardial perfusion and glucose metabolism imaging. J Nucl Cardiol 2006;13:e121–51.CrossRefGoogle Scholar
  52. 52.
    Links JM, Becker LC, Rigo P, et al. Combined corrections for attenuation, depth-dependent blur, and motion in cardiac SPECT a multicenter trial. J Nucl Cardiol 2000;7:414–25.PubMedCrossRefGoogle Scholar
  53. 53.
    Hsu BL, Case JA, Gegen LL, Hertenstein GK, Cullom SJ, Bateman TM, Attenuation correction of dynamic Tc99m-teboroxime myocardial perfusion SPECT [abstract]. J Nucl Cardiol 2004;11:S3.CrossRefGoogle Scholar
  54. 54.
    Hsu BL, Case JA, Bateman TM, Cullom SJ. Improved early post-stress TC99m-sestamibi myocardial perfusion SPECT using an energy-based scatter correction method [abstract]. J Nucl Cardiol 2005;12:S124.CrossRefGoogle Scholar
  55. 55.
    Garcia E. SPECT attenuation correction: an essential tool to realize nuclear cardiology’s manifest destiny. J Nucl Cardiol 2007;14:16–24.PubMedCrossRefGoogle Scholar

Copyright information

© the American Society of Nuclear Cardiology 2007

Authors and Affiliations

  • Bhupinder Singh
    • 4
    • 1
  • Timothy M. Bateman
    • 2
  • James A. Case
    • 3
  • Gary Heller
    • 4
    • 1
  1. 1.University of Connecticut School of MedicineFarmington
  2. 2.Mid America Heart InstituteKansas City
  3. 3.Cardiovascular Imaging TechnologyKansas City
  4. 4.Hartford HospitalHartford

Personalised recommendations