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On-line detection of human skin vapors

  • Pablo Martínez-Lozano
  • Juan Fernández de la MoraEmail author
Application Note

Abstract

Vapors released by the skin in the hand of one human subject are detected in real time by sampling them directly from the ambient gas surrounding the hand, ionizing them by secondary electrospray ionization (SESI, via contact with the charged cloud from an electrospray source), and analyzing them in a mass spectrometer with an atmospheric pressure source (API-MS). This gas-phase approach is complementary to alternative on-line surface ionization methods such as DESI and DART. A dominating peak of lactic acid and a complete series of saturated and singly unsaturated fatty acids (C12 to C18) are observed, in accordance with previous off-line studies by gas chromatography-mass spectrometry. Several other metabolites have been identified, including ketomonocarboxylic and hydroxymonocarboxylic acids.

Keywords

Dodecanoic Acid Extractive Electrospray Ionization Skin Emanation Skin Vapor Secondary Electrospray Ionization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Supplementary material

13361_2011_200601060_MOESM1_ESM.doc (47 kb)
Supplementary material, approximately 48 KB.

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Copyright information

© American Society for Mass Spectrometry 2009

Authors and Affiliations

  • Pablo Martínez-Lozano
    • 2
  • Juan Fernández de la Mora
    • 1
    Email author
  1. 1.Department of Mechanical EngineeringYale UniversityNew Haven
  2. 2.Parque Tecnológico de BoecilloSEADMValladolidSpain

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