Secondary electrospray ionization (SESI) of ambient vapors for explosive detection at concentrations below parts per trillion

  • Pablo Martínez-Lozano
  • Juan Rus
  • Gonzalo Fernández de la Mora
  • Marta Hernández
  • Juan Fernández de la Mora
Articles

Abstract

We determine the sensitivity of several commercial atmospheric pressure ionization mass spectrometers towards ambient vapors, ionized by contact with an electrospray of acidified or ammoniated solvent, a technique often referred to as secondary electrospray ionization (SESI). Although a record limit of detection of 0.2 × 10−12 atmospheres (0.2 ppt) is found for explosives such as PETN and 0.4 ppt for TNT (without preconcentration), this still implies the need for some 108–109 vapor molecules/s for positive identification of explosives. This extremely inefficient use of sample is partly due to low charging probability (∼10−4), finite ion transmission, and counting probability in the mass spectrometer (1/10 in quadrupoles), and a variable combination of duty cycle and background noise responsible typically for a 103 factor loss of useful signal.

Keywords

PETN Sample Flow Rate TATP Desorption Electrospray Ionization Explosive Detection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© American Society for Mass Spectrometry 2009

Authors and Affiliations

  • Pablo Martínez-Lozano
    • 1
    • 2
  • Juan Rus
    • 2
  • Gonzalo Fernández de la Mora
    • 2
  • Marta Hernández
    • 3
  • Juan Fernández de la Mora
    • 1
  1. 1.Mechanical Engineering DepartmentYale UniversityNew HavenUSA
  2. 2.SEADMValladolidSpain
  3. 3.CARTIFValladolidSpain

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