The McLafferty rearrangement: A personal recollection

  • Nico M. M. NibberingEmail author
Focus: McLafferty Rearrangement Account And Perspective


In this article, dedicated to Professor Fred McLafferty, I wish to recollect early observations with regard to the rearrangement named after him for 1-nitropropane and the methyl ester of γ-nitrobutyric acid. This rearrangement occurs for both cases clearly in a stepwise fashion, although for the ester, it occurs as a hidden rearrangement that catalyzes the tautomerization of the nitro group into its aci-form.


Nitro Group Nitro Compound Methyl Acetate Electron Ionization Mass Spectrum Ortho Hydrogen 
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Copyright information

© American Society for Mass Spectrometry 2004

Authors and Affiliations

  1. 1.Laser Center and Chemistry DepartmentVrije UniversityAmsterdamThe Netherlands

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