High Efficiency Photo-Induced Dissociation of Precursor Ions in a Tandem Time-of-Flight Mass Spectrometer

  • M. A. Seeterlin
  • P. R. Vlasak
  • D. J. Beussman
  • R. D. McLane
  • C. G. Enke


High efficiency photo-induced dissociation (PID) has been demonstrated in a tandem time-of-flight mass spectrometer. This instrument focuses isomass ion packets to temporal and spatial dimensions similar to those of the focused laser pulses from a high power excimer laser. This high density overlap of photons and ions yields highly efficient fragmentation and also provides high resolution selection of specific precursor ion mass-to-charge ratio values. Using 193 nm photon excitation of the molecular ion of bromobenzene (m/z = 1561, fragmentation, collection, and PID efficiencies af 79%, 132%, and 104%, respectively, were obtained. Characteristic fragmentations of toluene, nitrobenzene, acetophenone, triethylamine, N,N-diethylformamide, N-methylacetamide, and cyclohexene have also been demonstrated.


Bromobenzene Product Spectrum Focus Laser Pulse Laser Delay High Power Excimer Laser 
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Copyright information

© American Society for Mass Spectrometry 1993

Authors and Affiliations

  • M. A. Seeterlin
    • 1
  • P. R. Vlasak
    • 1
  • D. J. Beussman
    • 1
  • R. D. McLane
    • 1
  • C. G. Enke
    • 1
  1. 1.Department of ChemistryMichigan State UniversityEast LansingUSA

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