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A Cu2+ fluorescent chemosensor suitable for quantitative detection of tyrosinase in potatoes over a wide pH range

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Abstract

Cu2+ as an important trace element plays an essential role in various biologic processes due to the unique redox active nature. For this reason, much effort has been made to develop effective methods for Cu2+ detection. In this study, a novel structure fluorescent chemosensor, 1-(6-(((5-(5, 5-difluoro-1, 3, 7, 9-tetramethyl-5H-4λ4, 5λ4-dipyrrolo[1, 2-c:2', 1'-f][1, 3, 2] diazaborinin-10-yl)quinolin-8-yl)oxy)methyl)pyridin-2-yl)-N, N-bis(pyridin-2-ylmethyl)methanamine (1), was synthesized and characterized by 1H and 13C nuclear magnetic resonance spectroscopy, and electrospray ionization mass spectrometry. Sensor 1 showed an obviously “on–off” fluorescence response to Cu2+ with a 1:1 binding stoichiometry by UV–vis and fluorescence spectrophotometry. The detection limit of sensor 1 to Cu2+ was determined to be 1.9 µM, and the stable pH range for Cu2+ detection was from 3 to 13. Sensor 1 can be used for recognition and detection of tyrosinase in potatoes.

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Data availability

I would like to declare on behalf of my co-authors that the data supporting the findings of this study are available within the paper. Should any raw data files be needed in another format they are available from the corresponding author upon reasonable request. Source data are provided with this paper.

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Funding

The Science and Technology Innovation Project of Shanxi Agricultural University, 2020BQ18, xianjiao meng, Basic Research Program of Shanxi Province, 20210302124125, jingjing li.

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Authors and Affiliations

  1. Basic Sciences Depart, Shanxi Agricultural University, Jinzhong, 030801, China

    Xian-jiao Meng, Ya-ru Zhang, Jing-jing Li & Jun-xian Jia

  2. Institute of Theoretical Chemistry, Shandong University, Jinan, 250100, People’s Republic of China

    Jin-zhao Wang

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  1. Xian-jiao Meng
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Correspondence to Jing-jing Li.

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I would like to declare on behalf of my co-authors that the work described was original research that has not been published previously, and not under consideration for publication elsewhere, in whole or in part. All the authors listed have approved the manuscript that is enclosed.

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We would like to submit the enclosed manuscript entitled ‘A Copper Ion Fluorescent Chemical Sensor Suitable for Quantitative Detection of Tyrosinase in Potatoes over a Wide pH Range’, which we wish to be considered for publication in ‘Analytical Sciences’.

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Meng, Xj., Zhang, Yr., Li, Jj. et al. A Cu2+ fluorescent chemosensor suitable for quantitative detection of tyrosinase in potatoes over a wide pH range. ANAL. SCI. 40, 1167–1175 (2024). https://doi.org/10.1007/s44211-024-00546-2

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