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Table 1 Secondary outcomes

From: Assessing the clinical utilization of tranexamic acid by paramedics for patients with major trauma (ACUTE)

  TXA (n = 35) No TXA (n = 65)
Dose and regimen administered, n (%)
 1 g IV over 10 min 28 (80%)
 Other regimens 5 (14%)
 Not specified 2 (6%)
Received TXA despite contraindication(s) or lack of indication, n (%)
 Administration > 3 h after injury 0 (0%)
 History of thrombosis 0 (0%)
 Total mortality at 28 days, n (%) 2 (6%) 7 (11%)
Total thrombosis events, n (%)
 Deep vein thrombosis (DVT) 3 (9%) 2 (3%)
 Pulmonary embolism (PE) 1 (3%) 2 (3%)
Highest level of paramedic in attendance, n (%)a
 Primary care paramedic (PCP) 0 (0%) 1 (2%)
 Primary care paramedic with IV endorsement (PCP IV) 5 (14%) 32 (49%)
 Advanced care paramedic (ACP) 20 (57%) 22 (34%)
 Critical care paramedic (CCP) 10 (29%) 10 (15%)
Minutes between injury and paramedic arrival, mean [range] 22 [4–97] 23 [2–165]
Minutes between injury and first hospital arrival, mean [range] 78 [25–253] 64 [10–496]
Minutes between injury and tranexamic acid, mean [range] 50 [15–140]
 Sorted by Greater Vancouver/Victoria (n = 17) 33 [15–87]
 Sorted by Vancouver Island (n = 2) 71 [28–115]
 Sorted by Interior BC (n = 13) 69 [19–140]
 Sorted by Northern BC (n = 3) 49 [32–83]
  1. aCCP is the highest paramedic certification level in BC, followed by ACP, then PCP IV