Skip to main content

Advertisement

Log in

Mid- to Long-Term Results of Total Knee Arthroplasty for Charcot Arthropathy of the Knee

  • Original Article
  • Published:
Indian Journal of Orthopaedics Aims and scope Submit manuscript

Abstract

Background

Total knee arthroplasty (TKA) for Charcot arthropathy of the knee is considered controversial because of its higher complication rate compared with that of TKA for osteoarthritis. In this study, we investigated the clinical outcomes, survival rates, and complications of primary TKA for Charcot arthropathy.

Methods

We conducted a retrospective analysis of nine patients (12 knees) with Charcot arthropathy who underwent TKA. The mean age of the patients was 63.9 ± 9.4 years (range, 52–83 years). The most frequent causative disease was diabetes mellitus (three patients). Patients’ clinical outcomes, including the 2011 Knee Society Score and the range of motion, were compared between preoperative and the most recent postoperative data. The 5- and 10-year survival rates for aseptic revision, revision due to infection, and complications were examined. The mean follow-up period was 7.3 ± 3.9 years (range, 3–14 years).

Results

The 2011 Knee Society Score and the knee flexion angle significantly improved after TKA surgery (P < 0.05). The 5-year survival rates for aseptic revision, revision due to infection, and complications were 100%, 91.7%, and 83.3%, respectively; the 10-year survival rates for these parameters were the same. One patient underwent revision for insert replacement due to periprosthetic infection, and the other patient had varus/valgus instability due to soft tissue loosening.

Conclusions

The mid- to long-term results of TKA for Charcot arthropathy were generally favorable. Our findings indicate that TKA may be a viable treatment option for Charcot arthropathy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

Data Availability

Raw data were generated at Kobe University Graduate School of Medicine. Derived data supporting the findings of this study are available from the corresponding author Tomoyuki Matsumoto on request.

References

  1. Babazadeh, S., Stoney, J. D., Lim, K., & Choong, P. F. M. (2010). Arthroplasty of a Charcot knee. Orthopedic Reviews, 2(2), 17.

    Google Scholar 

  2. Kucera, T., Urban, K., & Sponer, P. (2011). Charcot arthropathy of the knee: A case-based review. Clin Rheumatol, 30(3), 425–428.

    Article  PubMed  Google Scholar 

  3. Illgner, U., Van Netten, J., Droste, C., Postema, K., Meiners, T., & Wetz, H. H. (2014). Diabetic charcot neuroarthropathy of the knee: Conservative treatment options as alternatives to surgery. Diabetes Care, 37(6), e129.

    Article  PubMed  Google Scholar 

  4. Kim, Y. H., Kim, J. S., & Oh, S. W. (2002). Total knee arthroplasty in neuropathic arthropathy. Journal of Bone and Joint Surgery. British Volume, 84(2), 216–219.

    Article  CAS  PubMed  Google Scholar 

  5. Yang, J. H., Yoon, J. R., Oh, C. H., & Kim, T. S. (2012). Primary total knee arthroplasty using rotating-hinge prosthesis in severely affected knees. Knee Surgery, Sports Traumatology, Arthroscopy, 20(3), 517–523.

    Article  PubMed  Google Scholar 

  6. Parvizi, J., Marrs, J., & Morrey, B. F. (2003). Total knee arthroplasty for neuropathic (Charcot) joints. Clinical Orthopaedics and Related Research, 416, 145–150.

    Article  Google Scholar 

  7. Zeng, M., Xie, J., & Hu, Y. (2016). Total knee arthroplasty in patients with Charcot joints. Knee Surgery, Sports Traumatology, Arthroscopy, 24(8), 2672–2677.

    Article  PubMed  Google Scholar 

  8. Tibbo, M. E., Chalmers, B. P., Berry, D. J., Pagnano, M. W., Lewallen, D. G., & Abdel, M. P. (2018). Primary total knee arthroplasty in patients with neuropathic (Charcot) arthropathy: contemporary results. Journal of Arthroplasty, 33(9), 2815–2820.

    Article  PubMed  Google Scholar 

  9. Bae, D. K., Song, S. J., Yoon, K. H., & Noh, J. H. (2009). Long-term outcome of total knee arthroplasty in Charcot joint: A 10- to 22-year follow-up. Journal of Arthroplasty, 24(8), 1152–1156.

    Article  PubMed  Google Scholar 

  10. Noble, P. C., Scuderi, G. R., Brekke, A. C., Sikorskii, A., Benjamin, J. B., Lonner, J. H., Chadha, P., Daylamani, D. A., Scott, W. N., & Bourne, R. B. (2012). Development of a new knee society scoring system. Clinical Orthopaedics and Related Research, 470, 20–32.

    Article  PubMed  Google Scholar 

  11. Koshino, T. (1991). Stage classifications, types of joint destruction, and bone scintigraphy in Charcot joint disease. Bulletin of the Hospital for Joint Diseases Orthopaedic Institute, 51(2), 205–217.

    CAS  PubMed  Google Scholar 

  12. Ewald, F. C. (1989). The Knee Society total knee arthroplasty roentgenographic evaluation and scoring system. Clinical Orthopaedics and Related Research, 248, 9–12.

    Article  ADS  Google Scholar 

  13. Kanda, Y. (2013). Investigation of the freely available easy-to-use software “EZR” for medical statistics. Bone Marrow Transplantation, 48(3), 452–458.

    Article  ADS  CAS  PubMed  Google Scholar 

  14. Kishore, J., Goel, M., & Khanna, P. (2010). Understanding survival analysis: Kaplan-Meier estimate. Int J Ayurveda Res, 1(4), 274.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Runner, R. P., Bellamy, J. L., Vu, C. C. L., Erens, G. A., Schenker, M. L., & Guild, G. N. (2017). Modified frailty index is an effective risk assessment tool in primary total knee arthroplasty. Journal of Arthroplasty, 32(9), S177–S182.

    Article  PubMed  Google Scholar 

  16. Kunutsor, S. K., Whitehouse, M. R., Blom, A. W., & Beswick, A. D. (2016). Patient-related risk factors for periprosthetic joint infection after total joint arthroplasty: A systematic review and meta-analysis. PLoS One, 11(3), e0150866.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Morgan, H., Battista, V., & Leopold, S. S. (2005). Constraint in primary total knee arthroplasty. Journal of American Academy of Orthopaedic Surgeons, 13(8), 515–524.

    Article  Google Scholar 

  18. Yilmaz, S., Cankaya, D., Deveci, A., First, A., Ozkurt, B., & Bozkurt, M. (2016). The impact of joint line restoration on functional results after hinged knee prosthesis. Indian Journal of Orthopaedics, 50, 136–145.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Nakajima, A., Tsuge, S., Aoki, Y., Sonobe, M., Shibata, Y., Sasaki, Y., & Nakagawa, K. (2013). Intra-articular giant heterotopic ossification following total knee arthroplasty for Charcot arthropathy. Case Reports in Orthopedics, 2013, 1–4.

    Article  Google Scholar 

  20. Yasin, M. N., Charalambous, C. P., Mills, S. P., Phaltankar, P. M., & Nurron, R. W. (2011). Early failure of a knee replacement in a neuropathic joint: A case report. Acta Orthop Belg, 77(1), 132–136.

    PubMed  Google Scholar 

  21. Yoshino, S., Fujimori, J., Kajino, A., Kiowa, M., & Uchida, S. (1993). Total knee arthroplasty in Charcot’s joint. Journal of Arthroplasty, 8(3), 335–340.

    Article  CAS  PubMed  Google Scholar 

  22. Whiteside, L. A. (1995). Exposure in difficult total knee arthroplasty using tibial tubercle osteotomy. Clinical Orthopaedics and Related Research, 321, 32–35.

    Google Scholar 

  23. Troyer, J., & Levine, B. R. (2009). Proximal tibia reconstruction with a porous tantalum cone in a patient with Charcot arthropathy. Orthopedics, 32(5), 358.

    PubMed  Google Scholar 

  24. Love, B., Alexander, B., Ray, J., Halstrom, J., Barranco, H., Solar, S., Singh, M., & Shah, A. (2020). Outcomes of tibiocalcaneal arthrodesis in high-risk patients: An institutional cohort of 18 patients. Indian Journal of Orthopaedics, 54(1), 14–21.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Acknowledgements

We would like to thank Editage (www.editage.com) for English language editing.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Tomoyuki Matsumoto.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

All participants provided informed consent prior to their participation.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Onoi, Y., Matsumoto, T., Nakano, N. et al. Mid- to Long-Term Results of Total Knee Arthroplasty for Charcot Arthropathy of the Knee. JOIO 58, 308–315 (2024). https://doi.org/10.1007/s43465-023-01094-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s43465-023-01094-z

Keywords

Navigation