Abstract
Introduction
Osteoporosis is a common diagnosis and comorbidity observed in patients with rheumatic diseases. It is frequently associated with conditions such as rheumatoid arthritis, spondyloarthropathy, systemic lupus erythematosus, and other autoimmune rheumatic diseases.
Conclusion
The incidence of osteoporosis is influenced by factors such as uncontrolled disease, prolonged and higher doses of steroid use, immobility, advanced age, and postmenopausal status. Achieving good control of the underlying disease, minimizing or avoiding the use of steroids for extended periods, and ensuring adequate supplementation of vitamin D and calcium are crucial in reducing the incidence of osteoporosis. Regular screening and appropriate management of osteoporosis can significantly decrease the associated morbidity and mortality.
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1007%2Fs43465-023-01024-z/MediaObjects/43465_2023_1024_Fig1_HTML.png)
Similar content being viewed by others
References
Mattia, C., Coluzzi, F., Celidonio, L., & Vellucci, R. (2016). Bone pain mechanism in osteoporosis: A narrative review. Clinical Cases in Mineral and Bone Metabolism, 13(2), 97–100.
Sawicki, P., Tałałaj, M., Życińska, K., Zgliczyński, W. S., & Wierzba, W. (2021). Comparison of the characteristics of back pain in women with postmenopausal osteoporosis with and without vertebral compression fracture: A retrospective study at a single osteoporosis center in Poland. Medical Science Monitor, 27, e929853–e929861.
Adami, G., Fassio, A., Rossini, M., Caimmi, C., Giollo, A., Orsolini, G., et al. (2019). Osteoporosis in rheumatic diseases. International Journal of Molecular Sciences, 20(23), 5867.
Shankar, S., Handa, R., Aneja, R., Marwaha, V., Ammini, A. C., & Aprajita, V. (2009). Bone mineral density in Indian women with rheumatoid arthritis. Rheumatology International, 29(4), 377–381.
Sivaprasad, R., Gopalakrishnan, M., Khichar, S., Shukla, R., Shukla, K., & Garg, M. K. (2023). Ab0274 Effect of rheumatoid arthritis on bone mineral density and its relationship with inflammatory milieu in patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 82(Suppl 1), 1318–1319.
McQueenie, R., Nicholl, B. I., Jani, B. D., Canning, J., Macdonald, S., McCowan, C., et al. (2020). Patterns of multimorbidity and their effects on adverse outcomes in rheumatoid arthritis: A study of 5658 UK Biobank participants. British Medical Journal Open, 10(11), e038829.
Elde, K. D., & Madsen, O. R. (2019). FRAX 10-yr fracture risk in rheumatoid arthritis—Assessments with and without bone mineral density may lead to very different results in the individual patient. Journal of Clinical Densitometry, 22(1), 31–38.
Kareem, R., Botleroo, R. A., Bhandari, R., Ogeyingbo, O. D., Ahmed, R., Gyawali, M., et al. (2021). The impact of rheumatoid arthritis on bone loss: Links to osteoporosis and osteopenia. Cureus, 13(8), e17519.
Dougados, M., & Baeten, D. (2011). Spondyloarthritis. Lancet., 377(9783), 2127–2137.
Fitzgerald, G. E., & O’Shea, F. D. (2017). The fascinating paradox of osteoporosis in axial spondyloarthropathy. Journal of Rheumatology, 44(12), 1767–1776.
Klingberg, E., Lorentzon, M., Mellström, D., Geijer, M., Göthlin, J., Hilme, E., et al. (2012). Osteoporosis in ankylosing spondylitis—Prevalence, risk factors and methods of assessment. Arthritis Research & Therapy, 14(3), R108.
Lim, M. J., & Kang, K. Y. (2020). A contemporary view of the diagnosis of osteoporosis in patients with axial spondyloarthritis. Frontiers in Medicine, 11(7), 569449.
van der Weijden, M. A. C., Claushuis, T. A. M., Nazari, T., Lems, W. F., Dijkmans, B. A. C., & van der Horst-Bruinsma, I. E. (2012). High prevalence of low bone mineral density in patients within 10 years of onset of ankylosing spondylitis: A systematic review. Clinical Rheumatology, 31(11), 1529–1535.
Fitzgerald, G. E., O’Dwyer, T., Mockler, D., O’Shea, F. D., & Wilson, F. (2020). Pharmacological treatment for managing bone health in axial spondyloarthropathy: Systematic review and meta-analysis. Rheumatology International, 40(9), 1369–1384.
Hinze, A. M., & Louie, G. H. (2016). Osteoporosis management in ankylosing spondylitis. Curr Treatm Opt Rheumatol., 2(4), 271–282.
Viapiana, O., Gatti, D., Idolazzi, L., Fracassi, E., Adami, S., Troplini, S., et al. (2014). Bisphosphonates vs infliximab in ankylosing spondylitis treatment. Rheumatology, 53(1), 90–94.
Mok, C., Li, O., Chan, K., Ho, L., & Hui, P. (2015). Effect of golimumab and pamidronate on clinical efficacy and MRI inflammation in axial spondyloarthritis: A 48-week open randomized trial. Scandinavian Journal of Rheumatology, 44(6), 480–486.
Wabl, M. (2010). The 9th International Congress on SLE. SAGE, 19, 1.
Sun, Y. N., Feng, X. Y., He, L., Zeng, L. X., Hao, Z. M., Lv, X. H., et al. (2015). Prevalence and possible risk factors of low bone mineral density in untreated female patients with systemic lupus erythematosus. BioMed Research International, 8(2015), e510514.
The Writing Group for the ISCD Position Development Conference. (2004). Diagnosis of osteoporosis in men, premenopausal women, and children. Journal of Clinical Densitometry 7(1):17–26.
Funding
None.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Ethical standard statement
This article does not contain any studies with human or animal subjects performed by the any of the authors.
Informed consent
For this type of study informed consent is not required.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Chandrashekara, S. Osteoporosis in Rheumatology. JOIO 57 (Suppl 1), 176–180 (2023). https://doi.org/10.1007/s43465-023-01024-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s43465-023-01024-z