Abstract
Purpose
The aim of this meta-analysis was to evaluate differences in functional outcomes between simultaneous bi-unicompartmental knee arthroplasty (Bi-UKA) and total knee arthroplasty (TKA) for the treatment of medial and lateral knee osteoarthritis.
Material and Methods
According to the PRISMA statement, a comprehensive search was conducted to identify studies reporting comparative results of the Bi-UKA versus the TKA. Of 953 titles, 6 studies met the inclusion criteria.
Results
A total of 286 patients were identified, of which 137 underwent Bi-UKA and 149 TKA. TKA reported a mean hip-knee-ankle (HKA) angle of 179.4 ± 2.4 compared to that in Bi-UKA measuring 177.2 ± 2.7 (p = 0.0001, 95% CI − 3.02 to − 1.38). No difference was found in the Western Ontario and McMaster Universities (WOMAC) pain (4 ± 1.6 and 4.2 ± 1.3 for Bi-UKA and TKA, respectively; p = 0.4996, 95% CI − 0.86 to 0.43). Bi-UKA was favorable in terms of WOMAC function (7.5 ± 1.9 and 9 ± 1.9 for Bi-UKA and TKA, respectively; p = 0.001, 95% CI − 2.29 to − 0.61) and WOMAC stiffness (1.6 ± 1 and 2.4 ± 0.7 for Bi-UKA and TKA, respectively; p = 0.0001, 95% CI − 1.18 to − 0.42). Bi-UKA showed a better Knee Society Score (KSS) in comparison to TKA (79.7 ± 7.8 and 75.4 ± 10.5 for Bi-UKA and TKA, respectively; p = 0.0021, 95% CI 1.58–7.02). The differences in postoperative outcomes scores between Bi-UKA and TKA were lower than their respective minimum clinically important differences.
Conclusions
When Bi-UKA and TKA are compared for the treatment of medial and lateral knee osteoarthritis, Bi-UKA are favorable in terms of WOMAC and KSS even though these values are lower than the minimum clinically important differences; moreover, similar postoperative hip-knee-ankle angle can be expected 3 years after Bi-UKA and TKA.
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References
Argenson, J.-N.A., Blanc, G., Aubaniac, J.-M., & Parratte, S. (2013). Modern unicompartmental knee arthroplasty with cement: A concise follow-up, at a mean of twenty years, of a previous report. Journal of Bone and Joint Surgery. American Volume, 95, 905–909. https://doi.org/10.2106/JBJS.L.00963
Winnock de Grave, P., Barbier, J., Luyckx, T., et al. (2018). Outcomes of a fixed-bearing, medial, cemented unicondylar knee arthroplasty design: survival analysis and functional score of 460 cases. Journal of Arthroplasty, 33, 2792–2799. https://doi.org/10.1016/j.arth.2018.04.031
Beard, D. J., Davies, L. J., Cook, J. A., et al. (2019). The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial. Lancet Lond Engl, 394, 746–756. https://doi.org/10.1016/S0140-6736(19)31281-4
Seo, S.-S., Kim, C.-W., Lee, C.-R., et al. (2019). Long-term outcomes of unicompartmental knee arthroplasty in patients requiring high flexion: An average 10-year follow-up study. Archives of Orthopaedic and Trauma Surgery, 139, 1633–1639. https://doi.org/10.1007/s00402-019-03268-7
Hauer, G., Sadoghi, P., Bernhardt, G. A., et al. (2020). Greater activity, better range of motion and higher quality of life following unicompartmental knee arthroplasty: A comparative case-control study. Archives of Orthopaedic and Trauma Surgery, 140, 231–237. https://doi.org/10.1007/s00402-019-03296-3
Lyons, M. C., MacDonald, S. J., Somerville, L. E., et al. (2012). Unicompartmental versus total knee arthroplasty database analysis: Is there a winner? Clinical Orthopaedics, 470, 84–90. https://doi.org/10.1007/s11999-011-2144-z
Gunston, F. H. (1971). Polycentric knee arthroplasty. Prosthetic simulation of normal knee movement. Journal of Bone and Joint Surgery. British Volume, 53, 272–277.
Goodfellow, J. W., & O’Connor, J. (1986). Clinical results of the Oxford knee. Surface arthroplasty of the tibiofemoral joint with a meniscal bearing prosthesis. Clinical Orthopaedics and Related Research, 205, 21–42.
Pandit, H., Mancuso, F., Jenkins, C., et al. (2017). Lateral unicompartmental knee replacement for the treatment of arthritis progression after medial unicompartmental replacement. Knee Surgery, Sports Traumatology, Arthroscopy, 25, 669–674. https://doi.org/10.1007/s00167-016-4075-4
Heekin, R., & Fokin, A. (2013). Incidence of bicompartmental osteoarthritis in patients undergoing total and unicompartmental knee arthroplasty: is the time ripe for a less radical treatment? The Journal of Knee Surgery, 27, 077–082. https://doi.org/10.1055/s-0033-1349401
Moher, D., Liberati, A., Tetzlaff, J., et al. (2009). Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. BMJ, 339, b2535. https://doi.org/10.1136/bmj.b2535
Grappiolo, G., Bruno, C. F., Loppini, M., et al. (2020). Conversion of fused hip to total hip arthroplasty: long-term clinical and radiological outcomes. Journal of Arthroplasty. https://doi.org/10.1016/j.arth.2020.09.030
Salaffi, F., Leardini, G., Canesi, B., et al. (2003). Reliability and validity of the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index in Italian patients with osteoarthritis of the knee. Osteoarthritis Cartilage, 11, 551–560. https://doi.org/10.1016/s1063-4584(03)00089-x
Insall, J. N., Dorr, L. D., Scott, R. D., & Scott, W. N. (1989). Rationale of the Knee Society clinical rating system. Clinical Orthopaedics and Related Research, 248, 13–14.
Mercurio, M., Gasparini, G., Carbone, E. A., et al. (2020). Personality traits predict residual pain after total hip and knee arthroplasty. International Orthopaedics, 44, 1263–1270. https://doi.org/10.1007/s00264-020-04553-6
Wells, G., Wells, G., & Shea, B. et al. (2014). The Newcastle–Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. undefined
Galasso, O., Gasparini, G., De Benedetto, M., et al. (2012). Tenotomy versus tenodesis in the treatment of the long head of biceps brachii tendon lesions. BMC Musculoskeletal Disorders, 13, 205. https://doi.org/10.1186/1471-2474-13-205
Sterne, J. A. C., Savović, J., Page, M. J., et al. (2019). RoB 2: A revised tool for assessing risk of bias in randomised trials. BMJ, 366, l4898. https://doi.org/10.1136/bmj.l4898
Familiari, F., Castricini, R., Galasso, O., et al. (2021). The 50 highest cited papers on rotator cuff tear. Arthroscopy, 37, 61–68. https://doi.org/10.1016/j.arthro.2020.07.044
Slavin, R. E. (1995). Best evidence synthesis: An intelligent alternative to meta-analysis. Journal of Clinical Epidemiology, 48, 9–18. https://doi.org/10.1016/0895-4356(94)00097-a
van Tulder, M., Furlan, A., Bombardier, C., et al. (2003). Updated method guidelines for systematic reviews in the cochrane collaboration back review group. Spine, 28, 1290–1299. https://doi.org/10.1097/01.BRS.0000065484.95996.AF
Fanelli, D., Mercurio, M., Gasparini, G., & Galasso, O. (2021). Predictors of meniscal allograft transplantation outcome: a systematic review. The Journal of Knee Surgery, 34, 303–321. https://doi.org/10.1055/s-0039-1695043
Mercurio, M., Castioni, D., Iannò, B., et al. (2019). Outcomes of revision surgery after periprosthetic shoulder infection: A systematic review. Journal of Shoulder and Elbow Surgery. https://doi.org/10.1016/j.jse.2019.02.014
Banger, M. S., Johnston, W. D., Razii, N., et al. (2020). Robotic arm-assisted bi-unicompartmental knee arthroplasty maintains natural knee joint anatomy compared with total knee arthroplasty: a prospective randomized. The Bone & Joint Journal, 102, 8.
Biazzo, A., Manzotti, A., & Confalonieri, N. (2018). Bi-unicompartmental versus total knee arthroplasty: Long term results. Acta Orthopaedica Belgica, 84, 237–244.
Confalonieri, N., Manzotti, A., Cerveri, P., & De Momi, E. (2009). Bi-unicompartmental versus total knee arthroplasty: A matched paired study with early clinical results. Archives of Orthopaedic and Trauma Surgery, 129, 1157–1163. https://doi.org/10.1007/s00402-008-0713-8
Dettmer, M., & Kreuzer, S. W. (2015). Bi-unicompartmental, robot-assisted knee arthroplasty. Operative Techniques in Orthopaedics, 25, 155–162. https://doi.org/10.1053/j.oto.2015.03.004
Fuchs, S., Tibesku, C. O., Genkinger, M., et al. (2004). Clinical and functional comparison of bicondylar sledge prostheses retaining all ligaments and constrained total knee replacement. Clinical Biomechanics, 19, 263–269. https://doi.org/10.1016/j.clinbiomech.2003.11.004
Blyth, M. J. G., Banger, M. S., Doonan, J., et al. (2021). Early outcomes after robotic arm-assisted bi-unicompartmental knee arthroplasty compared with total knee arthroplasty: a prospective, randomized controlled trial. Bone Jt J, 103B, 1561–1570. https://doi.org/10.1302/0301-620X.103B10.BJJ-2020-1919.R2
Moreland, J. R., Bassett, L. W., & Hanker, G. J. (1987). Radiographic analysis of the axial alignment of the lower extremity. Journal of Bone and Joint Surgery. American Volume, 69, 745–749.
Winnock de Grave, P., Luyckx, T., Claeys, K., et al. (2020). Higher satisfaction after total knee arthroplasty using restricted inverse kinematic alignment compared to adjusted mechanical alignment. Knee Surgery, Sports Traumatology, Arthroscopy. https://doi.org/10.1007/s00167-020-06165-4
Leiss, F., Götz, J. S., Maderbacher, G., et al. (2020). Pain management of unicompartmental (UKA) vs total knee arthroplasty (TKA) based on a matched pair analysis of 4144 cases. Scientific Reports, 10, 17660. https://doi.org/10.1038/s41598-020-74986-x
Leopold, S. S., & Porcher, R. (2017). Editorial: The minimum clinically important difference-the least we can do. Clinical Orthopaedics, 475, 929–932. https://doi.org/10.1007/s11999-017-5253-5
Clement, N. D., Bardgett, M., Weir, D., et al. (2018). What is the minimum clinically important difference for the WOMAC Index after TKA? Clinical Orthopaedics, 476, 2005–2014. https://doi.org/10.1097/CORR.0000000000000444
Lizaur-Utrilla, A., Gonzalez-Parreño, S., Martinez-Mendez, D., et al. (2020). Minimal clinically important differences and substantial clinical benefits for Knee Society Scores. Knee Surgery, Sports Traumatology, Arthroscopy, 28, 1473–1478. https://doi.org/10.1007/s00167-019-05543-x
Al-Dadah, O., Hawes, G., Chapman-Sheath, P. J., et al. (2020). Unicompartmental vs segmental bicompartmental vs total knee replacement: comparison of clinical outcomes. Knee Surgery & Related Research, 32, 47. https://doi.org/10.1186/s43019-020-00065-0
Parratte, S., Pauly, V., Aubaniac, J.-M., & Argenson, J.-N.A. (2010). Survival of bicompartmental knee arthroplasty at 5 to 23 years. Clinical Orthopaedics, 468, 64–72. https://doi.org/10.1007/s11999-009-1018-0
Dobrescu, A. I., Nussbaumer-Streit, B., Klerings, I., et al. (2021). Restricting evidence syntheses of interventions to English-language publications is a viable methodological shortcut for most medical topics: A systematic review. Journal of Clinical Epidemiology, 137, 209–217. https://doi.org/10.1016/j.jclinepi.2021.04.012
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Each author fulfils each of the authorship requirements. MM conceived and designed the study, performed the statistical analysis, participated in the acquisition and interpretation of data, and drafted the manuscript; GG conceived and coordinated the study and approved the final version of the manuscript as submitted; FF participated in the design of the study, in the acquisition and interpretation of data and drafted the manuscript; DC participated in the acquisition of data and drafted the manuscript; and OG conceived and coordinated the study and revised critically the manuscript. All authors read and approved the final manuscript.
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Mercurio, M., Gasparini, G., Familiari, F. et al. Outcomes of Bi-unicompartmental Versus Total Knee Arthroplasty for the Treatment of Medial and Lateral Knee Osteoarthritis: A Systematic Review and Meta-analysis of Comparative Studies. JOIO 56, 963–972 (2022). https://doi.org/10.1007/s43465-022-00628-1
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DOI: https://doi.org/10.1007/s43465-022-00628-1