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Quality of Life Evaluation Following Limb Lengthening Surgery in Patients with Achondroplasia

Indian Journal of Orthopaedics volume 54, pages 39–46 (2020)Cite this article

Abstract

Background

The primary objective of this study was to evaluate the quality of life following limb lengthening surgery in patients with achondroplasia. The complications and different lengthening techniques have and effects on mid-term results were also investigated.

Methods

We performed a retrospective, multicenter study by evaluating the records of patients with achondroplasia operated in our clinic between 1999 and 2014 for limb lengthening with a minimum follow-up of 3 years. Forty nine patients were underwent bilateral lower limb lengthening surgery and 21 of 49 patients underwent bilateral humerus lengthening surgery. Patients were evaluated by the Pediatric Quality of Life Inventory (PedsQL) 4.0 Generic Core Scales to assess the health-related quality of life (HRQOL) of children. Twenty patients with achondroplasia who had no lengthening surgery history were also evaluated with the PedsQL score as the control group.

Results

The average age at the time of first surgery was 6.17 years. The average follow-up period was 100.2 months. The average age at the time of study 14.70 ± 2.44 (11–18) years. There were significant differences between the patients with humeral lengthening and patients who did not undergo humeral lengthening in all scores. Transient complications had minimal effects on scores. Although all scores in the operated group were higher than non-operated patients with achondroplasia, there were no significant differences.

Conclusion

Quality of life was significantly improved as a result of humerus lengthening surgery of patients with achondroplasia, despite minor complications compared with Lower limb lengthening surgery.

Level of Evidence

Level III, case control study.

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Acknowledgements

Authors thank all siblings and parents of children with a chronic disease for their voluntarily participation.

Funding

There is no funding source.

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Affiliations

  1. Department of Orthopedics and Traumatology, Ankara Occupational and Environmental Diseases Hospital, Ankara, Turkey

    Sefa Giray Batıbay

  2. Department of Orthopedics and Traumatology, Faculty of Medicine, Istanbul University, Çapa Fatih, Istanbul, 34093, Turkey

    Halil İbrahim Balcı, Serkan Bayram, Mehmet Chodza & Cengiz Şen

  3. Department of Child and Adolescent Psychiatry, Faculty of Medicine, Istanbul University, Istanbul, Turkey

    Şeyda Göksoy

  4. Department of Orthopedics and Traumatology, Bakırköy Sadi Konuk Education and Research, Istanbul, Turkey

    Önder Murat Hürmeydan

  5. Department of Pediatric Endocrinology and Metabolism, Faculty of Medicine, Istanbul University, Istanbul, Turkey

    Aslı Derya Kardelen

  6. Department of Orthopedics and Traumatology, Unimed Center, Istanbul, Turkey

    Mehmet Kocaoğlu

Authors
  1. Sefa Giray Batıbay
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  2. Halil İbrahim Balcı
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  3. Serkan Bayram
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  4. Mehmet Chodza
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  5. Şeyda Göksoy
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  6. Önder Murat Hürmeydan
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  7. Aslı Derya Kardelen
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  8. Cengiz Şen
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  9. Mehmet Kocaoğlu
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Corresponding author

Correspondence to Serkan Bayram.

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The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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Ethical approval was given by the institutional review board.

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The procedures were explained in detail and written informed consent was obtained from all patients.

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Batıbay, S.G., Balcı, H.İ., Bayram, S. et al. Quality of Life Evaluation Following Limb Lengthening Surgery in Patients with Achondroplasia. JOIO 54, 39–46 (2020). https://doi.org/10.1007/s43465-020-00127-1

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  • DOI: https://doi.org/10.1007/s43465-020-00127-1

Keywords

  • Congenital short extremity
  • Lengthening rhythm
  • Congenital femoral deficiency
  • Congenital tibia pseudarthrosis
  • Quality of callus