Multicenter retrospective cohort study.
To compare pre-operative and post-operative EOSQ-24 scores in magnetically controlled growing rods (MCGR) and traditional growing rod (TGR) patients.
Summary of background data
Since the introduction of MCGR, early-onset scoliosis patients have been afforded a reduction in the number of surgeries compared to the TGR technique. However, little is known about (health-related quality of life) and burden of care outcomes between these surgical techniques.
This is a retrospective cohort study using a multicenter registry on patients with EOS undergoing MCGR or TGR between 2008 and 2017. The EOSQ-24 was administered at preoperative and postoperative 2-year assessments. The EOSQ-24 scores were compared between MCGR and TGR as well as preoperatively and postoperatively within each procedure.
110 patients were analyzed in this study (TGR, N = 32; MCGR, N = 78). There were no significant differences in preoperative age, gender, etiology, main coronal curve or maximum kyphosis between TGR and MCGR groups. Patients with TGR had averaged 3.9 surgical lengthenings and MCGR had averaged 7.7 non-invasive lengthenings by the 2-year follow-up. When changes in preoperative to postoperative scores were compared, MCGR had more improvements in pain, emotion, child satisfaction and parent satisfaction than TGR although there were no statistical significance. When analyzed separately, MCGR cohort had improvement in scores for all four domains and four sub-domains; while, TGR cohort only had improvement in financial burden domain and pulmonary function sub-domain.
Although there was no statistical significance, the improvement in pain, emotion and satisfaction scores was larger in MCGR than TGR. Since these areas can be influenced more by mental well-being than other sub-domains, the results may prove our hypothesis that compared to TGR, MCGR with reduced number of surgeries have better psychosocial effects.
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Thompson GH, Akbarnia BA, Campbell RM Jr (2007) Growing rod techniques in early-onset scoliosis. J Pediatr Orthop 27(3):354–361 (OD-2007/04/07. internal-pdf:/Thompson, G.H. et al_Growing Rod Techniques in EOS_JPO 2007.pdf)
Cheung KM-C, Cheung JP-Y, Samartzis D et al (2012) Magnetically controlled growing rods for severe spinal curvature in young children: a prospective case series. Lancet 379(9830):1967–1974. https://doi.org/10.1016/s0140-6736(12)60112-3
Flynn JM, Matsumoto H, Torres F, Ramirez N, Vitale MG (2012) Psychological dysfunction in children who require repetitive surgery for early onset scoliosis. J Pediatr Orthop 32(6):594–599. https://doi.org/10.1097/BPO.0b013e31826028ea
Bess S, Akbarnia BA, Thompson GH et al (2010) Complications of growing-rod treatment for early-onset scoliosis: analysis of one hundred and forty patients. J Bone Joint Surg Am 92(15):2533–2543. https://doi.org/10.2106/JBJS.I.01471
Matsumoto H, Williams BA, Corona J, Comer JS, Fisher PW, Neria Y, Roye BD, Roye DP, Vitale MG (2014) Psychosocial effects of repetitive surgeries in children with early onset scoliosis: are we putting them at risk? J Pediatr Orthop 34(2):172–178
Akbarnia BA, Pawelek JB, Cheung KMC et al (2014) Traditional growing rods versus magnetically controlled growing rods for the surgical treatment of early-onset scoliosis: a case-matched 2-year study. Spine Deform 2(6):493–497. https://doi.org/10.1016/j.jspd.2014.09.050
Doany ME, Deniz Olgun Z, Kinikli GI et al (2018) Health-related quality of life in early-onset scoliosis patients treated surgically: eosq scores in traditional growing rod versus magnetically controlled growing rods. Spine (Phila Pa 1976) 43(2):148–153. https://doi.org/10.1097/brs.0000000000002274
Matsumoto H, Williams B, Park HY et al (2016) The final 24-item early onset scoliosis questionnaires (EOSQ-24). J Pediatr Orthop. https://doi.org/10.1097/bpo.0000000000000799
Caldas JC, Pais-Ribeiro JL, Carneiro SR (2004) General anesthesia, surgery and hospitalization in children and their effects upon cognitive, academic, emotional and sociobehavioral development—a review. Paediatr Anaesth 14(11):910–915 OD-2004/10/27. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15500489
Kain ZN, Mayes LC, O’Connor TZ, Cicchetti DV (1996) Preoperative anxiety in children. Predictors and outcomes. Arch Pediatr Adolesc Med 150(12):1238–1245 OD-1996/12/01. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8953995
Kain ZN, Wang SM, Mayes LC, Caramico LA, Hofstadter MB (1999) Distress during the induction of anesthesia and postoperative behavioral outcomes. Anesth Analg 88(5):1042–1047. http://www.ncbi.nlm.nih.gov/pubmed/10320165. Accessed 9 Jul 2014
All participating sites in this study obtained IRB approval from their respective institutions prior to study initiation.
NuVasive Inc. provided research support and funded by Pediatric Spine Study Group (Grant number: CSSG0074) for this study.
Conflict of interest
Hiroko Matsumoto, PhDc: Grants from Scoliosis Research Society, grants from Pediatric Orthopaedic Society of North America. David L. Skaggs, MD, MMM: CHLA Foundation: Board or committee member; Grand Rounds: Paid consultant; Green Sun Medical: Stock or stock Options; Growing Spine Foundation: Board or committee member; Growing Spine Study Group: Board or committee member; Journal of Children’s Orthopaedics: Editorial or governing board; Medtronic: Other financial or material support; Nuvasive (Co-PI, Paid to Growing Spine Foundation): Research support; Orthobullets: Editorial or governing board; Paid consultant; Stock or stock Options; Orthopedics Today: Editorial or governing board; Spine Deformity: Editorial or governing board; Wolters Kluwer Health: Publishing royalties, financial or material support; ZimmerBiomet: IP royalties; Other financial or material support; Paid consultant; Paid presenter or speaker; Zipline Medical, Inc.: Stock or stock Options. Behrooz A. Akbarnia, MD: Grants, Royalties, Consultant: Nuvasive, Royalties: DePuy Synthes, Royalties: K2M, Stock/Stock options: Viseon, NociMed, grants from SeaSpine. Jeff B. Pawelek, BS: Volunteer board member, San Diego Spine Foundation. Tricia St. Hilaire, MPH: No conflicts of interest to disclose. Sonya Levine, BA: No conflicts of interest to disclose. Peter Sturm, MD, MBA: Personal fees and surgical advisory board from DePuy Synthes Spine, Consultant: NuVasive, Shareholder: Green Sun Medical, Editorial board: Journal of Children’s Orthopaedics. Francisco Javier Sanchez Perez-Grueso, MD: No conflicts of interest to disclose. Scott J. Luhmann, MD: Personal fees from Stryker, Medtronic, Orthopaediatrics, Globus, Wolters Kluwer, and Wishbone. Paul D. Sponseller, MD, MBA: Grants and personal fees from DePuy Synthes, personal fees from Globus, and Orthopediatrics. John T. Smith, MD: Royalties: Globus, Consultant: Nuvasive, Wishbone, Green Sun Medical, Board of Directors: Scoliosis Research Society, Children’s Spine Foundation. Klane K. White, MD: Grants and personal fees from Biomarin, grants from Ultragenyx, grants from Ascendis, grants from Theracon, personal fees from UptoDate.com. Michael G. Vitale, MD, MPH: Grants from Children’s Spine Foundation, grants from Orthopaedic Scientific Research Foundation, grants from SRS, grants from POSNA, Consultant: Stryker, Biomet, NuVasive, Royalties: Biomet. Pediatric Spine Study Group: Research support from POSNA, FDA, NuVasive, DePuy Synthes Spine, Growing Spine Foundation, Children’s Spine Foundation.
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Matsumoto, H., Skaggs, D.L., Akbarnia, B.A. et al. Comparing health-related quality of life and burden of care between early-onset scoliosis patients treated with magnetically controlled growing rods and traditional growing rods: a multicenter study. Spine Deform 9, 239–245 (2021). https://doi.org/10.1007/s43390-020-00173-7
- Early-onset scoliosis
- Magnetically controlled growing rods
- Traditional growing rods
- Health-related quality of life