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COVID-19 Vaccination and Reproductive Health: a Comprehensive Review for Healthcare Providers

  • General Gynecology: Review
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Abstract

With all the current misinformation on social media platforms about the COVID-19 vaccine and its potential effects on fertility, it is essential for healthcare providers to have evidenced-based research to educate their patients, especially those who are trying to conceive, of the risks to mothers and fetuses of being unvaccinated. It is well known that COVID-19 infection puts pregnant women at higher risk of complications, including ICU admission, placentitis, stillbirth, and death. In February of 2021, the American College of Obstetricians and Gynecologists (ACOG), the American Society for Reproductive Medicine (ASRM), and the Society for Maternal–Fetal Medicine (SMFM) released a statement denying any link between COVID vaccination and infertility. ASRM later confirmed and stated that “everyone, including pregnant women and those seeking to become pregnant, should get a COVID-19 vaccine”. In this review, we aim to provide a compilation of data that denies any link between vaccination and infertility for healthcare providers to be able to educate their patients based on evidence-based medicine. We also reviewed the effect of COVID-19 virus and vaccination on various parameters and processes that are essential to obtaining a successful pregnancy.

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Author notes

  1. Yaima Valdes, Braian Ledesma, and Raghuram V. Reddy contributed equally to this work.

Authors and Affiliations

  1. Desai Sethi Urology Institute, Miller School of Medicine, University of Miami, 1150 N.W. 14th St., Miami, FL, 33136, USA

    Yaima Valdes, Braian Ledesma, Raghuram V. Reddy, Romy Paz & Himanshu Arora

  2. Herbert Wertheim College of Medicine, Florida International University, Miami, FL, 33199, USA

    Raghuram V. Reddy

  3. Department of Medicine, Dr. Shankarrao Chavan Government Medical College, Nanded, Maharashtra, India

    Sameer Deshmukh

  4. South Florida Institute for Reproductive Medicine, IVFMD, 7300 SW 62nd Place, 4th Floor, South Miami, FL, 33143, USA

    Ineabelle Collazo, Maria Bustillo, Marta Montenegro, Juergen Eisermann & Katherine Palmerola

  5. John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, FL, 33143, USA

    Himanshu Arora

  6. The Interdisciplinary Stem Cell Institute, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA

    Himanshu Arora

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  1. Yaima Valdes
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Correspondence to Katherine Palmerola or Himanshu Arora.

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Valdes, Y., Ledesma, B., Reddy, R.V. et al. COVID-19 Vaccination and Reproductive Health: a Comprehensive Review for Healthcare Providers. Reprod. Sci. 31, 1215–1226 (2024). https://doi.org/10.1007/s43032-023-01428-0

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