Abstract
Although prior work indicates that exposure to multiple family risk factors negatively impacts adjustment in childhood and adolescence, few studies have examined whether children in high-risk families transition in and out of adversity during early childhood and whether patterns of change matter for adjustment in adolescence. Using data from a sample of 216 caregiver-child dyads participating in a study of prenatal cocaine exposure (116 exposed and 100 non-exposed; 50.9% girls), we used latent transition analysis to identify distinct profiles of early exposure to caregiver substance use (SU) and SU-related familial risk (caregiver psychological distress, exposure to violence, harshness, and low sensitivity) and the association between these profiles and adolescent well-being (i.e., hope, happiness, and life satisfaction). Assessments occurred when children were 13, 24, 36, and 48 months and during kindergarten (Mmonths = 66.16, SD = 4.47) and early adolescence (Myears = 13.26, SD = 0.88). Caregivers self-identified as 72.09% Black, 15.81% White, 10.23% Hispanic/Latinx, 1.40% other, and 0.47% American Indian. Four profiles of varying levels of exposure to caregiver SU and SU-related risks were identified from infancy to kindergarten: SU/family risks, no SU/low family risks, SU/negative parenting, and SU/low family risks. Most children stayed in the same profile (64.2%), while the rest transitioned between profiles. Children exposed to caregiver SU and family adversity had lower positive outcomes in adolescence. Stable membership in the SU/family risks profile had significant maladaptive consequences on adolescent well-being. Implications for research and the design of tailored interventions to promote well-being among at-risk youth are discussed.
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The data that support the findings of this study are available from the corresponding author, [DS], upon reasonable request.
References
Ackerman, B. P., Schoff, K., Levinson, K., Youngstrom, E., & Izard, C. E. (1999). The relations between cluster indexes of risk and promotion and the problem behaviors of 6- and 7-year-old children from economically disadvantaged families. Developmental Psychology, 35(6), 1355–1366. https://doi.org/10.1037/0012-1649.35.6.1355
Akaike, H. (1973). Information theory and an extension of the maximum likelihood principle. In B. N. Petrov & F. Csake (Eds.), Second international symposium on information theory (pp. 267–281). Akademiai Kiado.
Appleyard, K., Egeland, B., van Dulmen, M. H., & Alan Sroufe, L. (2005). When more is not better: The role of cumulative risk in child behavior outcomes. Journal of Child Psychology and Psychiatry, 46, 235–245. https://doi.org/10.1111/j.14697610.2004.00351.x
Avedissian, T., & Alayan, N. (2021). Adolescent well-being: A concept analysis. International Journal of Mental Health Nursing, 30(2), 357–367. https://doi.org/10.1111/inm.12833
Bridgett, D. J., & Mayes, L. C. (2011). Development of inhibitory control among prenatally cocaine exposed and non-cocaine exposed youths from late childhood to early adolescence: The effects of gender and risk and subsequent aggressive behavior. Neurotoxicology and Teratology, 33, 47–60. https://doi.org/10.1016/j.ntt.2010.08.002
Brody, G. H., Yu, T., Miller, G. E., & Chen, E. (2016). Resilience in adolescence, health, and psychosocial outcomes. Pediatrics, 138(6), e20161042. https://doi.org/10.1542/peds.2016-1042
Burchinal, M. R., Roberts, J. E., Hooper, S., & Zeisel, S. A. (2000). Cumulative risk and early cognitive development: A comparison of statistical risk models. Developmental Psychology, 36(6), 793–807. https://doi.org/10.1037/0012-1649.36.6.793
Bureau, J.-F., Easterbrooks, M. A., & Lyons-Ruth, K. (2009). Maternal depressive symptoms in infancy: Unique contribution to children’s depressive symptoms in childhood and adolescence? Development and Psychopathology, 21, 519–537. https://doi.org/10.1017/S0954579409000285
Caspi, A., Elder, G. H., & Bem, D. J. (1987). Moving against the world: Life-course patterns of explosive children. Developmental Psychology, 23(2), 308–406. https://doi.org/10.1111/j.1467-6494.1989.tb00487.x
Cicchetti, D. (1993). Developmental psychopathology: Reactions, reflections, projections. Developmental Review, 13, 471–502. https://doi.org/10.1006/drev.1993.1021
Clark, R. (1999). The parent-child early relational assessment: a factorial validity study. Educational and Psychological Measurement, 59, 821–846. https://doi.org/10.1177/00131649921970161954
Collins, L. M., & Lanza, S. T. (2010). Latent class and latent transition analysis: With applications in the social, behavioral, and health sciences. Wiley.
Cooper, B. R., & Lanza, S. T. (2014). Who benefits most from Head Start? Using latent class moderation to examine differential treatment effects. Child Development, 85(6), 2317–2338. https://doi.org/10.1111/cdev.12278
Copeland, W., Shanahan, L., Jane Costello, E., & Angold, A. (2009). Configurations of common childhood psychosocial risk factors. Journal of Child Psychology and Psychiatry, 50(4), 451–459. https://doi.org/10.1111/j.1469-7610.2008.02005.x
Costello, E. J., Copeland, W., & Angold, A. (2011). Trends in psychopathology across the adolescent years: What changes when children become adolescents, and when adolescents become adults? Journal of Child Psychology and Psychiatry, 52(10), 1015–1025. https://doi.org/10.1111/j.1469-7610.2011.02446.x
Deater-Deckard, K., Dodge, K. A., Bates, J. E., & Pettit, G. S. (1998). Multiple risk factors in the development of externalizing behavior problems: Group and individual differences. Development and Psychopathology, 10, 469–493. https://doi.org/10.1017/S0954579498001709
Derogatis, L. R. (1993). BSI brief symptom inventory: Administration, scoring, and procedure manual (4th ed.). National Computer Systems.
Diener, E., Suh, E. M., Lucas, R. E., & Smith, H. L. (1999). Subjective well-being: Three decades of progress. Psychological Bulletin, 125(2), 276–302. https://doi.org/10.1037/0033-2909.125.2.276
Dierkhising, C. B., Ford, J. D., Branson, C., Grasso, D. J., & Lee, R. (2019). Developmental timing of polyvictimization: Continuity, change, and association with adverse outcomes in adolescence. Child Abuse & Neglect, 87, 40–50. https://doi.org/10.1016/j.chiabu.2018.07.022
Duncan, G. J., Brooks-Gunn, J., Yeung, J., & Smith, J. R. (1998). How much does childhood poverty affect the life chances of children? American Sociological Review, 63(3), 406–423. https://doi.org/10.2307/2657556
Dunn, V. J., Abbott, R. A., Croudace, T. J., Wilkinson, P., Jones, P. B., Herbert, J., & Goodyer, I. M. (2011). Profiles of family-focused adverse experiences through childhood and early adolescence: The ROOTS project a community investigation of adolescent mental health. BMC Psychiatry, 11(1), 1–16. https://doi.org/10.1186/1471-244X-11-109
Edge, M. D., Ramel, W., Drabant, E. M., Kuo, J. R., Parker, K. J., & Gross, J. J. (2009). For better or worse? Stress inoculation effects for implicit but not explicit anxiety. Depression and Anxiety, 26(9), 831–837. https://doi.org/10.1002/da.20592
Edleson, J. L. (1999). Children’s witnessing of adult domestic violence. Journal of Interpersonal Violence, 14(8), 839–870. https://doi.org/10.1177/088626099014008004
Eiden, R. D., Foote, A., & Schuetze, P. (2007). Maternal cocaine use and caregiving status: Group differences in caregiver and infant risk variables. Addictive Behaviors, 32(3), 465–476. https://doi.org/10.1016/j.addbeh.2006.05.013
Eiden, R. D., Granger, D. A., Schuetze, P., & Veira, Y. (2011a). Child behavior problems among cocaine-exposed toddlers: Indirect and interactive effects. Development and Psychopathology, 23(2), 539–550. https://doi.org/10.1017/S0954579411000058
Eiden, R. D., Schuetze, P., Veira, Y., Cox, E., Jarrett, T. M., & Johns, J. M. (2011b). Cocaine exposure and children’s self-regulation: Indirect association via maternal harshness. Frontiers in Psychiatry, 2, 31. https://doi.org/10.3389/fpsyt.2011.00031
Eiden, R. D., Godleski, S., Schuetze, P., & Colder, C. R. (2015). Prenatal substance exposure and child self-regulation: Pathways to risk and protection. Journal of Experimental Child Psychology, 137, 12–29. https://doi.org/10.1016/j.jecp.2015.02.007
Ettekal, I., Eiden, R. D., Nickerson, A. B., & Schuetze, P. (2019). Comparing alternative methods of measuring cumulative risk based on multiple risk indicators: Are there differential effects on children’s externalizing problems? PLoS ONE, 14(7), e2219134. https://doi.org/10.1371/journal.pone.0219134
Evans, G. W., Li, D., & Whipple, S. S. (2013). Cumulative risk and child development. Psychological Bulletin, 139, 1342–1396. https://doi.org/10.1037/a0031808
Fals-Stewart, W., Birchler, G., & Kelley, M. (2004). The timeline followback spousal violence interview to assess physical aggression between intimate partners: Reliability and validity. Journal of Family Violence, 18, 131–142. https://doi.org/10.1023/A:1023587603865
Funk, B. A., Huebner, E. S., & Valois, R. F. (2006). Reliability and validity of a brief life satisfaction scale with a high school sample. Journal of Happiness Studies, 7(1), 41–54. https://doi.org/10.1007/s10902-005-0869-7
Goodman, S. H., Rouse, M. H., Connell, A. M., Broth, M. R., Christine, M. H., & Heyward, D. (2011). Maternal depression and child psychopathology: A meta-analytic review. Clinical Child and Family Psychology Review, 14, 19–27. https://doi.org/10.1007/s10567-010-0080-1
Gutman, L. M., Joshi, H., & Schoon, I. (2019). Developmental trajectories of conduct problems and cumulative risk from early childhood to adolescence. Journal of Youth and Adolescence, 48, 181–198. https://doi.org/10.1007/s10964-018-0971-x
Hatzis, D., Dawe, S., Harnett, P., & Barlow, J. (2017). Quality of caregiving in mothers with illicit substance use: A systematic review and meta-analysis. Substance Abuse: Research and Treatment, 11, 1–15. https://doi.org/10.1177/1178221817694038
Herbers, J. E., Cutuli, J. J., Jacobs, E. L., Tabachnick, A. R., & Kichline, T. (2019). Early childhood risk and later adaptation: A person-centered approach using latent profiles. Journal of Applied Developmental Psychology, 62, 66–76. https://doi.org/10.1016/j.appdev.2019.01.003
Höltge, J., Mc Gee, S. L., & Thoma, M. V. (2019). The curvilinear relationship of early-life adversity and successful aging: The mediating role of mental health. Aging & mental health, 23(5), 608–617. https://doi.org/10.1080/13607863.2018.1433635
Hussong, A. M., Wirth, R. J., Edwards, M. C., Curran, P. J., Chassin, L. A., & Zucker, R. A. (2007). Externalizing symptoms among children of alcoholic parents: Entry points for an antisocial pathway to alcoholism. Journal of Abnormal Psychology, 116(3), 529–542. https://doi.org/10.1037/0021-843x.116.3.529
Kelley, M. L., Lawrence, H. R., Milletich, R. J., Hollis, B. F., & Henson, J. M. (2015). Modeling risk for child abuse and harsh parenting in families with depressed and substance-abusing parents. Child Abuse & Neglect, 43, 42–52. https://doi.org/10.1016/j.chiabu.2015.01.017
Khemiri, L., Larsson, H., Kuja-Halkola, R., D’Onofrio, B. M., Lichtenstein, P., Jayaram-Lindström, N., & Latvala, A. (2020). Association of parental substance use disorder with offspring cognition: A population family-based study. Addiction, 115(2), 326–336. https://doi.org/10.1111/add.14813
Kochanska, G., & Murray, K. T. (2000). Mother–child mutually responsive orientation and conscience development: From toddler to early school age. Child Development, 71(2), 417–431. https://doi.org/10.1111/1467-8624.00154
Lanza, S. T., & Collins, L. M. (2008). A new SAS procedure for latent transition analysis: Transitions in dating and sexual risk behavior. Developmental Psychology, 44, 446–456. https://doi.org/10.1037/0012-1649.44.2.446
Lanza, S. T., Rhoades, B. L., Nix, R. L., Greenberg, M. T., & Conduct Problems Prevention Research Group. (2010). Modeling the interplay of multilevel risk factors for future academic and behavior problems: A person-centered approach. Development and Psychopathology, 22(2), 313–335. https://doi.org/10.1017/S0954579410000088
Lanza, S. T., Dziak, J. J., Huang, L., Wagner, A. T., & Collins, L. M. (2015). Proc LCA & Proc LTA users’ guide (Version 1.3.2). University Park: The Methodology Center, Penn State. Available from methodology.psu.edu
Letourneau, N. L., Tramonte, L., & Willms, J. D. (2013). Maternal depression, family functioning and children’s longitudinal development. Journal of Pediatric Nursing, 28, 223–234. https://doi.org/10.1016/j.pedn.2012.07.014
Lieb, R., Merikangas, K. R., Hofler, M., Pfister, H., Isensee, B., & Wittchen, H. U. (2002). Parental alcohol use disorders and alcohol use and disorders in offspring: A community study. Psychological Medicine, 32(1), 63–78. https://doi.org/10.1017/s0033291701004883
Lyubomirsky, S., & Lepper, H. (1999). A measure of subjective happiness: Preliminary reliability and construct validation. Social Indicators Research, 46, 137–155. https://doi.org/10.1023/A:1006824100041
Magnusson, D., & Bergman, L. R. (1988). Individual and variable-based approaches to longitudinal research on early risk factors. In M. Rutter (Ed.), Studies of psychosocial risk: The power of longitudinal data (pp. 45–61). Cambridge University Press.
McGorry, P., & Van Os, J. (2013). Redeeming diagnosis in psychiatry: Timing versus specificity. The Lancet, 381, 343–345. https://doi.org/10.1016/S01406736(12)61268-9
Meng, X.-L., & Rubin, D. B. (1992). Performing likelihood ratio tests with multiply-imputed data sets. Biometrika, 79, 103–111. https://doi.org/10.1093/biomet/79.1.103
Min, M. O., Minnes, S., Yoon, S., Short, E. J., & Singer, L. T. (2014). Self-reported adolescent behavioral adjustment: Effects of prenatal cocaine exposure. Journal of Adolescent Health, 55, 167–174. https://doi.org/10.1016/j.jadohealth.2013.12.032
Minnes, S., Lang, A., & Singer, L. (2011). Prenatal tobacco, marijuana, stimulant, and opiate exposure: Outcomes and practice implications. Addiction Science & Clinical Practice, 6(1), 57–70.
Minnes, S., Min, M. O., Short, E. J., Wu, M., Lang, A., Yoon, S., & Singer, L. T. (2016). Executive function in children with prenatal cocaine exposure (12–15 years). Neurotoxicology and Teratology, 57, 79–86. https://doi.org/10.1016/j.ntt.2016.07.002
Murray, L., Arteche, A., Fearon, P., Halligan, S., Goodyer, I., & Cooper, P. (2011). Maternal postnatal depression and the development of depression in offspring up to 16 years of age. Journal of the American Academy of Child & Adolescent Psychiatry, 50, 460–470. https://doi.org/10.1016/j.jaac.2011.02.001
Obradović, J., Shaffer, A., & Masten, A. S. (2012). Risk and adversity in developmental psychopathology: Progress and future directions. In L. C. Mayes & M. Lewis (Eds.), The Cambridge handbook of environment in human development (pp. 35–57). Cambridge University Press.
Parra, G. R., DuBois, D. L., & Sher, K. J. (2006). Investigation of profiles of risk factors for adolescent psychopathology: A person-centered approach. Journal of Clinical Child and Adolescent Psychology, 35(3), 386–402. https://doi.org/10.1207/s15374424jccp3503_4
Pastor, D. A., Barron, K. E., Miller, B. J., & Davis, S. L. (2007). A latent profile analysis of college students’ achievement goal orientation. Contemporary Educational Psychology, 32(1), 8–47. https://doi.org/10.1016/j.cedpsych.2006.10.003
Pratt, M. E., McClelland, M. M., Swanson, J., & Lipscomb, S. T. (2016). Family risk profiles and school readiness: A person-centered approach. Early Childhood Research Quarterly, 36, 462–474. https://doi.org/10.1016/j.ecresq.2016.01.017
Raby, K. L., Roisman, G. I., Fraley, R. C., & Simpson, J. A. (2015). The enduring predictive significance of early maternal sensitivity: Social and academic competence through age 32 years. Child Development, 86(3), 695–708. https://doi.org/10.1111/cdev.12325
Rhoades, B. L., Greenberg, M. T., Lanza, S. T., & Blair, C. (2011). Demographic and familial predictors of early executive function development: Contribution of a person-centered perspective. Journal of Experimental Child Psychology, 108(3), 638–662. https://doi.org/10.1016/j.jecp.2010.08.004
Ross, L. E., & Dennis, C. L. (2009). The prevalence of postpartum depression among women with substance use, an abuse history, or chronic illness: A systematic review. Journal of Women’s Health, 18(4), 475–486. https://doi.org/10.1089/jwh.2008.0953
Ross, D. A., Hinton, R., Melles-Brewer, M., Engel, D., Zeck, W., Fagan, L., & Mohan, A. (2020). Adolescent well-being: A definition and conceptual framework. Journal of Adolescent Health, 67(4), 472–476. https://doi.org/10.1016/j.jadohealth.2020.06.042
Roy, A. L., & Raver, C. C. (2014). Are all risks equal? Early experiences of poverty-related risk and children’s functioning. Journal of Family Psychology, 28(3), 391–400. https://doi.org/10.1037/a0036683
Rutter, M. (2012). Resilience as a dynamic concept. Development and Psychopathology, 24(2), 335–344. https://doi.org/10.1037/abn0000043
Rutter, M. (1979). Protective factors in children’s responses to stress and disadvantage. In M. W. Kent & J. E. Rolf (Eds.), Primary prevention of psychopathology: Social competence in children (Vol. 3), 324 –338. University Press in New England
Sameroff, A. J., Seifer, R., Baldwin, A., & Baldwin, C. (1993). Stability of intelligence from preschool to adolescence: The influence of social and family risk factors. Child Development, 64(1), 80–97. https://doi.org/10.1111/j.1467-8624.1993.tb02896.x
Schwarz, G. (1978). Estimating the dimension of a model. The Annals of Statistics, 6, 461–464. http://www.jstor.org/stable/2958889
Seligson, J. L., Huebner, E. S., & Valois, R. F. (2003). Preliminary validation of the brief multidimensional students' life satisfaction scale (BMSLSS). Social Indicators Research, 61, 121–145. https://doi.org/10.1023/A:1021326822957
Shisler, S., Homish, G., Molnar, D. S., & Eiden, R. D. (2016). Predictors of changes in smoking from 3rd trimester to 9 months post-partum. Drug and Alcohol Dependence, 18, 1–4. https://doi.org/10.1016/j.drugalcdep.2014.09.633
Shonkoff, J. P., Garner, A. S., The Committee on Psychological Aspects of Child and Family Health, the Committee on Early Childhood, Adoption, and Dependent Care, Section of Developmental and Behavioral Pediatrics, Siegel, B. S., Dobbins, M. I., Earls, M. F., McGuinn, L., Pascoe, J., Wood, D. L. (2012). The lifelong effects of early childhood adversity and toxic stress. Pediatrics, 129, e232–e246https://doi.org/10.1542/peds.2011-2663
Singer, L. T., Nelson, S., Short, E., Min, M. O., Lewis, B., Russ, S., & Minnes, S. (2008). Prenatal cocaine exposure: Drug and environmental effects at 9 years. The Journal of Pediatrics, 153(1), 105–111. https://doi.org/10.1016/j.jpeds.2008.01.001
Smith, V. C., Wilson, C. R., Ryan, S. A., Gonzalez, P. K., Patrick, S. W., Quigley, J., ... & Walker, L. R. (2016). Families affected by parental substance use. Pediatrics, 138(2), e20161575. https://doi.org/10.1542/peds.2016-1575
Snyder, C. R., Hoza, B., Pelham, W. E., Rapoff, M., Ware, L., Danovsky, M., Highberger, L., Ribinstein, H., & Stahl, K. J. (1997). The development and validation of the Children’s Hope Scale. Journal of Pediatric Psychology, 22(3), 399–421. https://doi.org/10.1093/jpepsy/22.3.399
Sobell, M. B., Sobell, L. C., Klajner, F., Pavan, D., & Basian, E. (1986). The reliability of a timeline method for assessing normal drinker college students’ recent drinking history: Utility for alcohol research. Addictive Behaviors, 11(2), 149–161. https://doi.org/10.1016/0306-4603(86)90040-7
Sroufe, L. A. (1990). Considering normal and abnormal together: The essence of developmental psychopathology. Development and Psychopathology, 2(4), 335–347. https://doi.org/10.1017/S0954579400005769
Steptoe, A., Deaton, A., & Stone, A. A. (2015). Subjective wellbeing, health, and ageing. The Lancet, 385(9968), 640–648. https://doi.org/10.1016/S0140-6736(13)61489-0
Trentacosta, C. J., Hyde, L. W., Shaw, D. S., Dishion, T. J., Gardner, F., & Wilson, M. (2008). The relations among cumulative risk, parenting, and behavior problems during early childhood. Journal of Child Psychology and Psychiatry, 49(11), 1211–1219. https://doi.org/10.1111/j.1469-7610.2008.01941.x
Veira, Y., Finger, B., Schuetze, P., Colder, C. R., & Eiden, R. D. (2014). Maternal cocaine use and child behavior problems: Role of parenting and child exposure to violence. Psychology of Violence, 4, 266–280. https://doi.org/10.1037/a0036157
Velleman, R., & Templeton, L. J. (2016). Impact of parents’ substance misuse on children: An update. Bjpsych Advances, 22(2), 108–117. https://doi.org/10.1192/apt.bp.114.014449
Vera, J., Granero, R., & Ezpeleta, L. (2012). Father’s and mother’s perceptions of parenting styles as mediators of the effects of parental psychopathology on antisocial behavior in outpatient children and adolescents. Child Psychiatry & Human Development, 43(3), 376–392. https://doi.org/10.1007/s10578-011-0272-z
Wadman, R., Hiller, R. M., & St Clair, M. C. (2020). The influence of early familial adversity on adolescent risk behaviors and mental health: Stability and transition in family adversity profiles in a cohort sample. Development and Psychopathology, 32(2), 437–454. https://doi.org/10.1017/S0954579419000191
Walden, B., Iacono, W. G., & McGue, M. (2007). Trajectories of change in adolescent substance use and symptomatology: Impact of paternal and maternal substance use disorders. Psychology of Addictive Behaviors, 21, 35–43. https://doi.org/10.1037/0893-164X.21.1.35
Wendell, A. D. (2013). Overview and epidemiology of substance abuse in pregnancy. Clinical Obstetrics and Gynecology, 56(1), 91–96. https://doi.org/10.1097/GRF.0b013e31827feeb9
Whitaker, R. C., Orzol, S. M., & Kahn, R. S. (2006). Maternal mental health, substance use, and domestic violence in the year after delivery and subsequent behavior problems in children at age 3 years. Archives of General Psychiatry, 63, 551–560. https://doi.org/10.1001/archpsyc.63.5.551
Yan, N., Ansari, A., Sattler, K. M., & Zhou, N. (2019). Change in risk patterns across early childhood and children’s first-grade adjustment. Journal of Child and Family Studies, 28(2), 490–504. https://doi.org/10.1007/s10826-018-1291-1
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Seay, D.M., Ivanova, M.Y., Nickerson, A.B. et al. Family Risk Exposure Profiles During Early Childhood: Developmental Processes and Adolescent Well-Being. ADV RES SCI 4, 151–170 (2023). https://doi.org/10.1007/s42844-023-00090-4
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DOI: https://doi.org/10.1007/s42844-023-00090-4