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Seroprevalence of Dengue, Chikungunya, and Zika viruses antibodies in a cohort of asymptomatic pregnant women in a low-income region of Minas Gerais, Brazil, 2018–2019

  • Clinical Microbiology - Short Communication
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Abstract

Dengue, Chikungunya, and Zika viruses are arthropod-borne viruses (arboviruses) that infect millions of individuals in tropical and subtropical regions. In the Americas, arboviruses represent a major public health problem, especially among vulnerable groups such as the elderly, children, and pregnant women. In this study, the seroprevalence of IgM or IgG against these arboviruses in pregnant, young women in the city of Diamantina, Minas Gerais, Brazil, and the influence of sociodemographic factors on the incidence/prevalence of infection in this group were investigated. A cross-sectional investigation was conducted on a total of 135 pregnant women for Dengue and Chikungunya IgM and 88 pregnant women for Zika IgG. Dengue IgM was found on the serum of twenty participants (14.8%) and only one woman (0.7%) tested positive for Chikungunya IgM. Zika IgG was found in three (3.4%) participants and 2 women who tested positive for Zika virus were also positive for Dengue virus IgM. Although the arboviruses seroprevalence was higher frequency among young (20–25 years old), brown and high school women, with a monthly income of 1–3 minimum wages, no association between these sociodemographic factors and arboviruses seroprevalence was found.

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Fig. 1

Data availability

The data presented in this study are available on request from the corresponding author.

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Acknowledgements

The authors would like to acknowledge the Centro Integrado de Pós-Graduação e Pesquisa em Saúde at the Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, Minas Gerais, Brazil, for providing equipment and technical support for experiments.

Funding

This research was funded by Minas Gerais Research Foundation (FAPEMIG), grant number APQ-00824–18, and was financed by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brasil (CAPES)—Finance Code 001.

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Authors and Affiliations

  1. Programa Multicêntrico de Pós-Graduação Em Ciências Fisiológicas, Universidade Federal Dos Vales Do Jequitinhonha E Mucuri, Diamantina, MG, Brazil

    Juliane Duarte Santos, Bruna Caroline Chaves Garcia, Sanny Lara da Silva Lage, Etel Rocha-Vieira & Danilo Bretas de Oliveira

  2. Programa de Pós-Graduação Em Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil

    Kamila Lorene Soares Rocha

  3. Programa de Pós-Graduação Em Ciências da Saúde, Universidade Federal Dos Vales Do Jequitinhonha E Mucuri, Diamantina, MG, Brazil

    Thyago José Silva, Etel Rocha-Vieira & Danilo Bretas de Oliveira

  4. Departamento de Nutrição, Universidade Federal Dos Vales Do Jequitinhonha E Mucuri, Diamantina, MG, Brazil

    Mariana de Souza Macedo & Romero Alves Teixeira

Authors
  1. Juliane Duarte Santos
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  2. Bruna Caroline Chaves Garcia
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  3. Kamila Lorene Soares Rocha
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  4. Thyago José Silva
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  5. Sanny Lara da Silva Lage
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  6. Mariana de Souza Macedo
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  8. Etel Rocha-Vieira
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  9. Danilo Bretas de Oliveira
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Contributions

Conceptualization: ERV and DBdO; data collection: MSM and RAT; data analyses: JDS, BCCG and ERV; serology assay: JDS, KLSR, TJS, and SLSL; manuscript preparation: JDS and ERV; manuscript review: JDS, BCCG, ERV, and DBdO. Supervision: ERV and DBdO. All authors have read and approved the final version of the manuscript.

Corresponding authors

Correspondence to Etel Rocha-Vieira or Danilo Bretas de Oliveira.

Ethics declarations

Ethics approval

The study was conducted in accordance with the Declaration of Helsinki and approved by the Institutional Review Board of Universidade Federal dos Vales do Jequitinhonha e Mucuri (protocol code: 2.073.117).

Conflict of interest

The authors declare no competing interests.

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Responsible Editor: Flavio Guimaraes Fonseca

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Santos, J.D., Garcia, B.C.C., Rocha, K.L.S. et al. Seroprevalence of Dengue, Chikungunya, and Zika viruses antibodies in a cohort of asymptomatic pregnant women in a low-income region of Minas Gerais, Brazil, 2018–2019. Braz J Microbiol 54, 1853–1858 (2023). https://doi.org/10.1007/s42770-023-01054-7

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