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Production strategies and biotechnological relevance of microbial lipases: a review

  • Biotechnology and Industrial Microbiology - Review
  • Published:
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Abstract

Lipases are enzymes that catalyze the breakdown of lipids into long-chain fatty acids and glycerol in oil-water interface. In addition, they catalyze broad spectrum of bioconversion reactions including esterification, inter-esterification, among others in non-aqueous and micro-aqueous milieu. Lipases are universally produced from plants, animals, and microorganisms. However, lipases from microbial origin are mostly preferred owing to their lower production costs, ease of genetic manipulation etc. The secretion of these biocatalysts by microorganisms is influenced by nutritional and physicochemical parameters. Optimization of the bioprocess parameters enhanced lipase production. In addition, microbial lipases have gained intensified attention for a wide range of applications in food, detergent, and cosmetics industries as well as in environmental bioremediation. This review provides insights into strategies for production of microbial lipases for potential biotechnological applications.

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Acknowledgements

The financial support of the National Research Foundation (NRF) of South Africa toward this research is hereby acknowledged. Opinions expressed and conclusions arrived at are those of the authors and are not necessarily to be attributed to the NRF.

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  1. Discipline of Microbiology, School of Life Sciences, College of Agriculture, Engineering and Science, University of KwaZulu-Natal (Westville campus), Private Bag X54001, Durban, 4000, Republic of South Africa

    Adegoke Isiaka Adetunji & Ademola Olufolahan Olaniran

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Adetunji, A.I., Olaniran, A.O. Production strategies and biotechnological relevance of microbial lipases: a review. Braz J Microbiol 52, 1257–1269 (2021). https://doi.org/10.1007/s42770-021-00503-5

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