Abstract
Malaria transmission dynamics and entomological indices on highlands have been a subject of interest due to their altitude. Until now, no data exist on malaria entomological indices for Mambilla Plateau; a highland region prone to malaria epidemics in Taraba, North-East Nigeria. We studied malaria entomological indices across five localities (Nguroje, Yelwa, Gembu, Kakara and Mayo Selbe) on the Plateau. Anopheles mosquitoes were collected using Pyrethrum Spray Catch method (PSC) from nineteen (19) households per locality. Anopheles mosquitoes collected were identified morphologically using standard keys. Members of Anopheles gambiae sl. were further identified molecularly. All samples were tested for Plasmodium falciparum circumsporozoite protein (CSP) using Enzyme-Linked Immunosorbent Assay (ELISA). A total of 569 Anopheles mosquitoes comprising four species; An. gambiae, An. coustani, An. funestus, and An. pharoensis were collected. Mosquito abundance and species diversity reduced with increase in altitude. An. gambiae ss. (93.92%) was the most predominant sibling species of An. gambiae complex on the highland. The presence of sporozoites was detected in 24 (4.22%) samples and all the samples were An. gambiae sl. Man biting rate of Anopheles spp. ranged between 0.02 and 2.56. Entomological inoculation rate (EIR) decreased with increase in altitude with the lowest EIR at Nguroje (0.007 bites/person/night). Results revealed that malaria transmission is ongoing on Mambilla Plateau albeit at a low rate, therefore, efforts should be geared towards malaria vector control at this time when the entomological indices suggest low malaria transmission.
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References
Afrane YA, Githeko AK, Yan G (2012 Feb) The ecology of Anopheles mosquitoes under climate change: case studies from the effects of deforestation in east african highlands, vol 1249. Annals of the New York Academy of Sciences, pp 204–210. 1
Alonso D, Bouma MJ, Pascual M (2011) Epidemic malaria and warmer temperatures in recent decades in an East African highland. Proceedings of the Royal Society B: Biological Sciences. Jun 7;278(1712):1661-9
Animut A, Gebre-Michael T, Balkew M, Lindtjørn B (2012 Dec) Abundance and dynamics of anopheline larvae in a highland malarious area of south-central Ethiopia. Parasites & vectors 5(1):1–9
Apinjoh TO, Ouattara A, Titanji VP, Djimde A, Amambua-Ngwa A (2019 Dec) Genetic diversity and drug resistance surveillance of Plasmodium falciparum for malaria elimination: is there an ideal tool for resource-limited sub-saharan Africa? Malar J 18(1):1–2
Autino B, Noris A, Russo R, Castelli F (2012) Epidemiology of malaria in endemic areas.Mediterranean journal of hematology and infectious diseases. ; 4(1)
Beck-Johnson LM, Nelson WA, Paaijmans KP, Read AF, Thomas MB, Bjørnstad ON (2013 Nov) The effect of temperature on Anopheles mosquito population dynamics and the potential for malaria transmission. PLoS ONE 14(11):e79276
Bødker R, Akida J, Shayo D, Kisinza W, Msangeni HA, Pedersen EM, Lindsay SW Relationship between altitude and intensity of malaria transmission in the Usambara Mountains, Tanzania. Journal of medical entomology. 2003 Sep 1;40(5):706 – 17
Caputo A, Garavelli PL (2016) Climate, environment and transmission of malaria. Infez Med 2:93–104
Cox J, Craig MH, Le sueur D, Sharp B Mapping Malaria Risk in the Highlands of Africa. Mapping Malaria Risk in Africa/ highland Malaria Project (MARA/HIMAL). Technical Report 1999; MARA/Durban, London. London School of Hygiene and Tropical Medicine
Fanello C, Santolamazza F, Della Torre A (2002 Dec) Simultaneous identification of species and molecular forms of the Anopheles gambiae complex by PCR-RFLP. Medical and veterinary entomology. 16:461–4644
Gillies MT, Coetzee M (1987) A supplement to the Anophelinae of Africa South of the Sahara. Publ S Afr Inst Med Res 55:1–43
Githeko AK, Lindsay SW, Confalonieri UE, Patz JA (2000) Climate change and vector-borne diseases: a regional analysis. Bull World Health Organ 78:1136–1147
Nigeria National Population Commission, National Malaria Control Programme (Nigeria) (2012) ICF International (Firm), MEASURE DHS (Program). Nigeria Malaria Indicator Survey 2010. NPC, NMCP and ICF International;
Maxwell CA, Chambo W, Mwaimu M, Magogo F, Carneiro IA, Curtis CF (2003 Dec) Variation of malaria transmission and morbidity with altitude in Tanzania and with introduction of alphacypermethrin treated nets. Malar J 2(1):1–9
Minakawa N, Sonye G, Mogi M, Githeko A, Yan G (2002) The effects of climatic factors on the distribution and abundance of malaria vectors in Kenya. Journal of medical entomology. Nov 1;39(6):833 – 41
Molineaux L, Gramiccia G, World Health Organization (1980) The Garki project: research on the epidemiology and control of malaria in the Sudan savanna of West Africa. World Health Organization
Mwangangi JM, Muturi EJ, Muriu SM, Nzovu J, Midega JT, Mbogo C (2013 Dec) The role of Anopheles arabiensis and Anopheles coustani in indoor and outdoor malaria transmission in Taveta District, Kenya, vol 6. Parasites & vectors, pp 1–9. 1
National Bureau of Statistics. Federal Republic of Nigeria. Annual Abstract of Statistics 2016. p 62
Nonvignon J, Aryeetey GC, Malm KL, Agyemang SA, Aubyn VN, Peprah NY, Bart-Plange CN, Aikins M (2016 Dec) Economic burden of malaria on businesses in Ghana: a case for private sector investment in malaria control. Malar J 15(1):1–0
Okorie PN, Popoola KO, Awobifa OM, Ibrahim KT, Ademowo GO (2014 Aug) Species composition and temporal distribution of mosquito populations in Ibadan, Southwestern Nigeria. J Entomol Zool Stud 2(4):164
Omotayo AI, Ande AT, Oduola AO, Adelaja OJ, Adesalu O, Jimoh TR, Ghazali AI, Awolola ST (2022) Multiple insecticide resistance mechanisms in urban population of Anopheles coluzzii (Diptera: Culicidae) from Lagos, South-West Nigeria. Acta Tropica. Mar 1;227:106291
Omukunda E, Githeko A, Ndong’a MF, Mushinzimana E, Atieli H, Wamae P (2013) Malaria vector population dynamics in highland and lowland regions of western Kenya. Journal of vector borne diseases. Jun 1;50(2):85
The PMI VectorLink Project (January 2022) The PMI VectorLink Nigeria Project Annual Entomology Report, October 2020–September 2021. VectorLink, Abt Associates Inc, Rockville, MD
Scott JA, Brogdon WG, Collins FH (1993) Identification of single specimens of the Anopheles gambiae complex by the polymerase chain reaction. The American journal of tropical medicine and hygiene. Oct 1;49(4):520-9
Shililu JI, Maier WA, Seitz HM, Orago AS (1998) Seasonal density, sporozoite rates and entomological inoculation rates of Anopheles gambiae and Anopheles funestus in a high-altitude sugarcane growing zone in Western Kenya. Tropical Medicine & International Health: TM & IH. Sep 1;3(9):706 – 10
Smith DL, Cohen JM, Chiyaka C, Johnston G, Gething PW, Gosling R, Buckee CO, Laxminarayan R, Hay SI, Tatem AJ (2013 Aug) A sticky situation: the unexpected stability of malaria elimination. Philosophical Trans Royal Soc B: Biol Sci 5(1623):20120145
Tchuinkam T, Simard F, Lélé-Defo E, Téné-Fossog B, Tateng-Ngouateu A, Antonio-Nkondjio C, Mpoame M, Toto JC, Njiné T, Fontenille D, Awono-Ambéné HP (2010 Dec) Bionomics of Anopheline species and malaria transmission dynamics along an altitudinal transect in western Cameroon. BMC Infect Dis 10:1–2
Vajda ÉA, Webb CE (2017 Mar) Assessing the risk factors associated with malaria in the Highlands of Ethiopia: what do we need to know?. Tropical medicine and infectious disease. 2:41
Van Emden HF, Service MW (2014) Pest and vector control. Cambridge University Press, p p10
Wandiga SO, Opondo M, Olago D, Githeko A, Githui F, Marshall M, Downs T, Opere A, Oludhe C, Ouma GO, Yanda PZ (2010 Apr) Vulnerability to epidemic malaria in the highlands of Lake Victoria basin: the role of climate change/variability, hydrology and socio-economic factors. Clim Change 99(3):473–497
Wanjala CL, Waitumbi J, Zhou G, Githeko AK (2011 Dec) Identification of malaria transmission and epidemic hotspots in the western Kenya highlands: its application to malaria epidemic prediction. Parasites & vectors 4(1):1–3
Wirtz RA, Zavala F, Charoenvit Y, Campbell GH, Burkot TR, Schneider I, Esser KM, Beaudoin RL, Andre RG (1987) Comparative testing of monoclonal antibodies against Plasmodium falciparum sporozoites for ELISA development. Bull World Health Organ 65(1):39
World Health Organization (2021) World malaria report 2021. World Health Organization, Geneva, Switzerland
Zhou G, Munga S, Minakawa N, Githeko AK, Yan G (2007 Jul) Spatial relationship between adult malaria vector abundance and environmental factors in western Kenya highlands. Am J Trop Med Hyg 77(1):29–35
Acknowledgements
Our profound gratitude goes to all staff of Molecular Entomology and Vector Control Research Laboratory, Nigeria Institute of Medical Research, Yaba, Lagos, Nigeria.
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The research was supported by Taraba State University, Jalingo, Nigeria.
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Garba, L.C., Oyieke, F., Owino, A.E. et al. Entomological indices of malaria vectors across different altitudes on Mambilla Plateau, Taraba, Nigeria. Int J Trop Insect Sci 43, 843–849 (2023). https://doi.org/10.1007/s42690-023-00995-8
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DOI: https://doi.org/10.1007/s42690-023-00995-8