Structural insights into the molecular mechanisms of pectinolytic enzymes

Abstract

Pectinolytic enzymes produced by a large variety of organisms are well characterized concerning their physiological and pathological activities during modification or degradation of the complex plant cell wall. The exponential growth in structural information of these enzymes over past decades has rendered insights into functionally relevant residues, active sites and molecular basis of the enzymatic mechanism, which in turn, endorses its usage in industrial applications. This review highlights a comprehensive and up to date summary of structural information and the structure–function correlation of pectinolytic enzymes.

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Acknowledgements

The author would like to thank Dr. Bamaprasad Bag at Institute of Minerals and Materials Technology, Bhubaneswar and Dr. Hirak Chakraborty, Department of Chemistry, Sambalpur University for critical reading of the manuscript and fruitful suggestions.

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Correspondence to Bhawani Prasad Bag.

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Kanungo, A., Bag, B.P. Structural insights into the molecular mechanisms of pectinolytic enzymes. J Proteins Proteom 10, 325–344 (2019). https://doi.org/10.1007/s42485-019-00027-5

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Keywords

  • Pectinolytic enzymes
  • Pectinase
  • Homogalacturonan
  • Xylogalacturonan
  • Rhamnogalacturonan
  • Hydrolase
  • Lyase
  • Esterase
  • Structural fold