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Cerebral Venous Thrombosis in a Young Athlete—an Unusual but Preventable Cause


Evaluation of cerebral venous sinus thrombosis (CVST) can be challenging, with the etiology often being unrecognized. We report a case of CVST occurring secondary to anti-cancer medication abuse in a young bodybuilder. A 20-year-old male athlete with history of regular gym exercise presented with acute onset behavioral abnormalities and cognitive deficits. Brain magnetic resonance imaging (MRI) showed signal abnormalities in bilateral thalami, with venography showing venous thrombosis. A detailed history highlighted an unusual cause for CVST. Our report suggests that unsupervised drug abuse amongst young athletes is an overlooked and preventable cause of CVST. To the best of our knowledge, this is the first such report.

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Fig. 1

Data Availability

Data used for the case report is available with the corresponding author.



cerebral venous sinus thrombosis


magnetic resonance imaging


Japanese encephalitis


cerebrospinal fluid


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SW analyzed and interpreted data regarding clinical treatment and outcome. AA analyzed and interpreted data regarding MRI. SJ and VP supervised the management of patient, and were major contributors to the preparation of manuscript.

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Correspondence to Siddharth Warrier.

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Patient’s consent for use of data and publication of image received.

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Warrier, S., Arora, A., Jha, S. et al. Cerebral Venous Thrombosis in a Young Athlete—an Unusual but Preventable Cause. SN Compr. Clin. Med. 3, 340–342 (2021).

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  • Cerebral venous sinus thrombosis
  • Young stroke
  • Tamoxifen
  • Athlete
  • Bodybuilder
  • Drug abuse