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Minimally Invasive Surgery for Patients with Spontaneous Intracerebral Hemorrhage: a Book Reopened

SN Comprehensive Clinical Medicine volume 2, pages 640–643 (2020)Cite this article

Abstract

In contrast to remarkable recent gains made in the outcomes of patients with ischemic stroke, outcomes for patients with hemorrhagic stroke (spontaneous intracerebral hemorrhage [ICH]) remain poor. The results of past surgical trials for ICH—motivated by the hypothesis that patients would benefit from interventions to reduce intracranial hypertension associated with clot burden and prevent secondary injury induced by blood in the brain parenchyma—have to date been disappointing. Here, we review the results of the recently completed Minimally Invasive Surgery Plus Alteplase for Intracerebral Hemorrhage Evacuation III trial, which suggest that minimally invasive ICH evacuation may be clinically beneficial, but only when significant hematoma evacuation is achieved, and discuss ongoing minimally invasive surgical evacuation trials for ICH.

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Funding

S.D. is the recipient of an Early Researcher Award from the Province of Ontario.

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Authors and Affiliations

  1. Division of Neurosurgery, St. Michael’s Hospital, University of Toronto, Toronto, Canada

    Sunit Das

  2. Department of Neurosurgery, Emory University, Atlanta, USA

    Gustavo Pradilla

  3. Department of Neurosurgery, University of California, San Diego, USA

    Alexander Khalessi

Authors
  1. Sunit Das
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  2. Gustavo Pradilla
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  3. Alexander Khalessi
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Corresponding author

Correspondence to Sunit Das.

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Conflict of Interest

S.D. is on the advisory board of the Subcortical Surgery Group. G.P. is the recipient of a Clinical Trial Research Grant from NICO Corporation and is a PI for ENRICH.

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Das, S., Pradilla, G. & Khalessi, A. Minimally Invasive Surgery for Patients with Spontaneous Intracerebral Hemorrhage: a Book Reopened. SN Compr. Clin. Med. 2, 640–643 (2020). https://doi.org/10.1007/s42399-020-00287-z

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  • DOI: https://doi.org/10.1007/s42399-020-00287-z

Keywords

  • Stroke
  • Hemorrhagic stroke
  • Intracerebral hemorrhage
  • Minimally invasive surgery