The presence of hydroxylated polycyclic aromatic hydrocarbons (OH-PAHs) in urine has been used to assess the exposure, metabolic activation, and risks of these carcinogens. Thus, this study is aimed at investigating the concentration and risk of OH-PAHs among commercial motorcyclists in southern, Nigeria. Urine samples were collected early in the morning from forty volunteer commercial cyclists who participated in this study. The OH-PAHs were quantified in the urines using high performance liquid chromatography (HPLC) after hydrolysis. Result showed that ∑8 OH-PAHs varied significantly, ranging from 0.04 to 24.48 ng mL− 1 for all the urine samples collected. The occurrence pattern follows the order: 3-OHFlu > 1-OHPhen > 2-OHNap > 2-OHFlu > 1-OHNap > 3-OHPhen > 4-OHPhen > 1-OHPyr. There was no significant variation of OH-PAHs with personal factors such as smoking, age and years of working. However, the hazard index (HI) values for the OH-PAHs were above 1 and indicated that there is adverse non-carcinogenic risk for the commercial motorcyclists. The use of personal protective equipment is therefore encouraged among commercial motorcyclists.
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Tesi, G.O., Kpomah, E.D., Ossai, J.C. et al. Hydroxylated Polycyclic Aromatic Hydrocarbons in Urines of Commercial Motorcyclists in Southern Part of Nigeria. Chemistry Africa 6, 3145–3152 (2023). https://doi.org/10.1007/s42250-023-00702-7