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3D bioprinting for the endocrine glands

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Abstract

Endocrine glands regulate homeostasis of the body with the hormones they secrete. Regeneration and/or replacement of malfunctioning endocrine glands is a global need since the diseases associated with them affect more people year by year. Tissue engineering is an emerging promising field for the patients who suffer organ failure with recent pioneering clinical applications. Success in tissue engineering strategy depends on the use of proper cells, bioactive factors that stimulate the activities of these cells, and scaffolds that are produced to recapitulate the structure and support the function of engineered tissues. 3D bioprinting is a developing strategy for the production of living tissues by using bioinks to produce the cell-laden scaffolds in a layer-by-layer procedure. In this review, major endocrine glands, their functionalities, and tissue engineering strategies to produce them are covered with special emphasis to their biofabrication through 3D bioprinting.

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Authors and Affiliations

  1. Department of Biomedical Engineering, Ankara University, Ankara, Turkey

    Mervesu Gokyurek & Pinar Yilgor Huri

  2. Gulhane Research And Training Hospital Department of General Surgery, University of Health Sciences, Ankara, Turkey

    Kerim Bora Yilmaz

  3. Department of Medical and Surgical Research, Institute of Health Sciences, Hacettepe University, Ankara, Turkey

    Kerim Bora Yilmaz

  4. MEDITAM, Ankara University Medical Design Research and Application Center, Ankara, Turkey

    Pinar Yilgor Huri

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  1. Mervesu Gokyurek
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Correspondence to Pinar Yilgor Huri.

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Gokyurek, M., Yilmaz, K.B. & Yilgor Huri, P. 3D bioprinting for the endocrine glands. emergent mater. 3, 441–452 (2020). https://doi.org/10.1007/s42247-020-00085-2

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