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Photosynthetic biomaterials: applications of photosynthesis in algae as oxygenerator in biomedical therapies

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Abstract

For most organisms, molecular oxygen is indispensable for normal physiological metabolism; in humans, prolonged hypoxia in tissues can induce many diseases, exemplified by cardiovascular disease, chronic wounds, and tissue necrosis. Therefore, the oxygen in our environment is vital for life. As a main source of oxygen in the natural world that transforms light energy into chemical energy and oxygen, photosynthesis has been widely studied in scientific research and used in production of food, fuel, and medicine. In recent years, photosynthesis has become more closely involved in biomedicine and has been widely used in photodynamic therapy, tissue regeneration, transplantation, and in treatment of specific diseases. This review summarizes innovative applications of photosynthesis in biomedical research and highlights the theory and implications of clinical treatment for specific diseases.

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reproduced with permission from Ref. [73], and c, d reproduced with permission from Ref. [74]

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Reproduced with permission from Ref. [94], b Reproduced with permission from Ref. [95], and c Reproduced with permission from Ref. [96]

Fig. 8

reproduced with permission from Ref. [97], c reproduced with permission from Ref. [100], and d reproduced with permission from Ref. [102]

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Acknowledgements

This work was supported by Grants from the National Natural Science Foundation of China (Nos. 81671918 and 81372072), the Zhejiang Provincial Medical and Healthy Science Foundation of China (Nos. 2021452516, 2019ZD028, and 2018KY874), and the National Key Research Program of China (No. 2016YFC1101004).

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Authors and Affiliations

  1. Department of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou, 310016, China

    Yong Wang, Yanan Xue, Tao Zhang, Qingqing Fang, Mingyuan Jin, Xiaofeng Wang, Zhengcai Wang, Yanyan Hu, Wanyi Zhao, Dong Lou & Wei-Qiang Tan

  2. Department of Plastic Surgery, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, N1 Shangcheng Road, Yiwu, 322000, China

    Wei-Qiang Tan

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  1. Yong Wang
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  2. Yanan Xue
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  3. Tao Zhang
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  5. Mingyuan Jin
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  10. Dong Lou
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Contributions

YW investigated and summarized the literature, and wrote the original draft. YNX, TZ, QQF, MYJ, and XFW conducted deep review and editing. ZCW, YYH, and WYZ helped revise the paper and gave some advice. DL and WQT supervised and applied for funds. All authors have read and approved this manuscript for publication.

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Correspondence to Dong Lou or Wei-Qiang Tan.

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This study does not contain any studies with human or animal subjects performed by any of the authors.

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Wang, Y., Xue, Y., Zhang, T. et al. Photosynthetic biomaterials: applications of photosynthesis in algae as oxygenerator in biomedical therapies. Bio-des. Manuf. 4, 596–611 (2021). https://doi.org/10.1007/s42242-021-00129-4

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