Abstract
Purpose
The presence in older patients of an interatrial block (IAB) may be a predictor of atrial fibrillation (AF). The objective of the study was to assess in a group of very older participants: the prevalence of IAB, its association with the presence of functional and cognitive status, of new AF diagnosis and mortality after 2-year of follow-up.
Methods
A prospective subcohort of the OCTABAIX population-based study with 75 inhabitants, all 85-year-olds, at baseline in sinus rhythm were assessed. Functional and cognitive status, nutritional risk, and previous falls were recorded. Participants were classified according to the presence or absence of IAB.
Results
23 patients had IAB (30.7%). We did not observe significant differences regarding gender, comorbidity, functional status, nutritional risk and global geriatric assessment according to interatrial conduction. The patients with IAB had statistically significant better cognitive performance (p = 0.029) and a lower number of previous falls (p = 0.008). During the 2 years follow-up 3 participants (4%) died; without statistical differences between both groups. A non-significant trend to a higher incidence of new-onset AF was observed in patients with IAB (8.7 vs. 6.1%; p = 0.652).
Conclusions
Nearly one-third of very older patients with sinus rhythm have IAB. They had a tendency to higher incidence of AF and no association with mortality after 2 years of follow-up.
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References
Conde D, Baranchuk A, Bayés de Luna A (2015) Advanced interatrial block as a substrate of supraventricular tachyarrhythmias: a well recognized syndrome. J Electrocardiol 48:135–140
Bacharova L, Wagner GS (2015) The time for naming the interatrial block syndrome: Bayes syndrome. J Electrocardiol 48:133–134
Bernal E, Bayés-Genís A, Ariza-Solé A et al (2018) Interatrial block, frailty and prognosis in elderly patients with myocardial infarction. J Electrocardiol 51:1–7
Ariyarajah V, Puri P, Kranis M, Wilner DA, Spodick DH (2006) Prevalence of interatrial block in the Program of All-Inclusive Care for the Elderly (PACE). Am J Geriatr Cardiol 15:174–177
O’Neal WT, Zhang ZM, Loehr LR, Chen LY, Alonso A, Soliman EZ (2016) Electrocardiographic advanced interatrial block and atrial fibrillation risk in the general population. Am J Cardiol 117:1755–1759
Martínez-Sellés M, Massó-van Roessel A, Álvarez-García J et al (2016) Investigators of the cardiac and clinical characterization of centenarians (4C) registry. Interatrial block and atrial arrhythmias in centenarians: prevalence, associations, and clinical implications. Heart Rhythm 13:645–651
Ferrer A, Formiga F, Padrós G, Badia T, Almeda J, Octabaix GE (2017) The Octabaix study. Baseline assessment and 5 years of follow-up. Rev Esp Geriatr Gerontol 52:44–52
Formiga F, Ferrer A, Mimbrera D, Badia T, Fernández C, Pujol R (2012) Grupo de Estudio Octabaix. High rate of anticoagulation therapy in oldest old subjects with atrial fibrillation: the Octabaix study. J Am Med Dir Assoc 13:8–10
Bayés de Luna A, Platonov P, Cosio FG et al (2012) Interatrial blocks. A separate entity from left atrial enlargement: a consensus report. J Electrocardiol 45:445–451
Singh-Manoux A, Fayosse A et al (2017) Atrial fibrillation as a risk factor for cognitive decline and dementia. Eur Heart J 38:2612–2618
Formiga F, Ferrer A, Mestre D, Brasé A, Soldevila L, Corbella X (2016) High rate of mortality in Spanish community-dwelling population aged 85 with atrial fibrillation after three years of follow-up: the Octabaix study. Australas J Ageing 35:216–219
Massó-van Roessel A, Escobar-Robledo LA, Dégano RI et al (2017) Analysis of the association between electrocardiographic p-wave characteristics and atrial fibrillation in the REGICOR study. Rev Esp Cardiol (Engl Ed) 70:841–847
Acknowledgements
Members of the Octabaix Study: J Almeda (Unitat de Suport a la Recerca de Costa de Ponent, IDIAP J Gol), T Badia (ABS Martorell Urbano), A Lobato (ABS Sant Andreu de la Barca), C Fernández (CAP Rambla), A Ferrer (CAP El Pla), F Formiga (UFISS de Geriatría, Servicio de Medicina Interna, Hospital Universitari de Bellvitge), A Gil (ABS Sant Andreu de la Barca), MJ Megido (ABS Just Oliveras), G Padrós (Laboratori Clínic L’Hospitalet), M Sarró (CAP Florida Nord) and A Tobella (ABS Martorell Rural).
Funding
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
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The authors declare that they have no conflict of interest.
Ethical approval
The study was approved by the institutional ethics committee of the Jordi Gol Institute for Primary Care Research IDIAP.
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All patients—or the caregivers for those cognitively impaired participants—gave their written informed consent before enrollment.
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Formiga, F., Guerrero, C., Ferrer, A. et al. Prevalence and clinical significance of interatrial block in very older persons. Eur Geriatr Med 9, 155–159 (2018). https://doi.org/10.1007/s41999-018-0039-1
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DOI: https://doi.org/10.1007/s41999-018-0039-1