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Adenomyose

Ein aktueller Überblick

Adenomyosis

An actual review

  • Originalien
  • Published:
Journal für Gynäkologische Endokrinologie/Österreich Aims and scope

Zusammenfassung

Relevante Fortschritte konnten in Hinblick auf Verständnis und Diagnose der Adenomyose im letzten Jahrzehnt erzielt werden. Der folgende Artikel stellt einen Überblick über Erkenntnisse in Pathogenese, Möglichkeiten und Grenzen der Bildgebung sowie konservative und chirurgische Behandlungsmöglichkeiten der Adenomyose vor.

Abstract

In the last decade, relevant progress could be achieved in understanding and diagnosing adenomyosis. The following article gives a comprehensive overview of pathogenesis, achievements and limitations in imaging techniques as well as the treatment options of adenomyosis.

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Literatur

  1. García-Solares J, Donnez J, Olivier Donnez, Dolmans M‑M (2018) Pathogenesis of uterine adenomyosis: invagination or metaplasia? Fertil Steril 109(3):371–379

    Article  Google Scholar 

  2. Van den Bosch T, Dueholm M, Leone FP, Valentin L, Rasmussen CK, Votino A, Van Schoubroeck D, Landolfo C, Installé AJ, Guerriero S, Exacoustos C, Gordts S, Benacerraf B, D’Hooghe T, De Moor B, Brölmann H, Goldstein S, Epstein E, Bourne T, Timmerman D (2015) Terms, definitions and measurements to describe sonographic features of myometrium and uterine masses: a consensus opinion from the Morphological Uterus Sonographic Assessment (MUSA) group. Ultrasound Obstet Gynecol 46(3):284–298. https://doi.org/10.1002/uog.14806

    Article  PubMed  Google Scholar 

  3. Van den Bosch T, de Bruijn AM, de Leeuw RA, Dueholm M, Exacoustos C, Valentin L, Bourne T, Timmerman D, Huirne JAF (2019) Sonographic classification and reporting system for diagnosing adenomyosis. Ultrasound Obstet Gynecol 53(5):576–582. https://doi.org/10.1002/uog.19096

    Article  PubMed  Google Scholar 

  4. Bazot M, Daraï E (2018) Role of transvaginal sonography and magnetic resonance imaging in the diagnosis of uterine adenomyosis. Fertil Steril 109(3):389–397

    Article  Google Scholar 

  5. Osada H (2018) Uterine adenomyosis and adenomyoma: the surgical approach. Fertil Steril. 109(3):406−417

    PubMed  Google Scholar 

  6. Zaloudek C, Norris HJ (1987) Mesenchymal tumors of the uterus. In: Kurmann RJ (Hrsg) Blaunstein’s pathology of the female genital tract. 3. Aufl. Springer, New York

    Chapter  Google Scholar 

  7. Leyendecker G, Wildt L (2011) A new concept of endometriosis and adenomyosis: tissue injury and repair (TIAR). Horm Mol Biol Clin Investig. 5(2):125–142

    CAS  PubMed  Google Scholar 

  8. Azziz R (1989) Adenomyosis: current perspectives. Obstet Gynecol Clin North Am. 16(1):221–235

    CAS  PubMed  Google Scholar 

  9. Campo S, Campo V, Benagiano G (2012) Infertility and adenomyosis. Obstet Gynecol Int. 2012:786132. https://doi.org/10.1155/2012/786132

    Article  PubMed  Google Scholar 

  10. Younes G, Tulandi T (2017) Effects of adenomyosis on in vitro fertilization treatment outcomes: a meta-analysis. Fertil Steril. 108(3):483–490.e3

    Article  Google Scholar 

  11. Lazzeri L, Di Giovanni A, Exacoustos C, Tosti C, Pinzauti S, Malzoni M, Petraglia F, Zupi E (2014) Preoperative and Postoperative Clinical and Transvaginal Ultrasound Findings of Adenomyosis in Patients With Deep Infiltrating Endometriosis. Reprod Sci. 21(8):1027–1033

    Article  Google Scholar 

  12. Exacoustos C, Brienza L, Di Giovanni A, Szabolcs B, Romanini ME, Zupi E, Arduini D (2011) Adenomyosis: three-dimensional sonographic findings of the junctional zone and correlation with histology. Ultrasound Obstet Gynecol. 37(4):471–479

    Article  CAS  Google Scholar 

  13. Luciano DE, Exacoustos C, Albrecht L, LaMonica R, Proffer A, Zupi E, Luciano AA (2013) Three-dimensional ultrasound in diagnosis of adenomyosis: histologic correlation with ultrasound targeted biopsies of the uterus. J Minim Invasive Gynecol. 20(6):803–810

    Article  Google Scholar 

  14. Nam JH, Lyu GS (2015) Abdominal ultrasound-guided transvaginal myometrial core needle biopsy for the definitive diagnosis of suspected adenomyosis in 1032 patients: a retrospective study. J Minim Invasive Gynecol. 22(3):395–402. https://doi.org/10.1016/j.jmig.2014.08.006. Epub 2014 Aug 11

    Article  PubMed  Google Scholar 

  15. Gordts S, Grimbizis G, Campo R (2018) Symptoms and classification of uterine adenomyosis, including the place of hysteroscopy in diagnosis. Fertil Steril. 109(3):380–388.e1

    Article  Google Scholar 

  16. Exacoustos C, Luciano D, Corbett B, De Felice G, Di Feliciantonio M, Luciano A, Zupi E (2013) The uterine junctional zone: a 3-dimensional ultrasound study of patients with endometriosis. Am J Obstet Gynecol. 209(3):248.e1–7

    Article  Google Scholar 

  17. Sharma K, Bora MK, Venkatesh BP, Barman P, Roy SK, Jayagurunathan U, Sellamuthu E, Moidu F (2015) Role of 3D Ultrasound and Doppler in Differentiating Clinically Suspected Cases of Leiomyomaand Adenomyosis of Uterus.J Clin Diagn Res. 9(4):QC08–12. https://doi.org/10.7860/JCDR/2015/12240.5846. Epub 2015

    Article  Google Scholar 

  18. Gordts S, Grimbizis G, Campo R (2018) Symptoms and classification of uterine adenomyosis, including the place of hysteroscopy in diagnosis. Fertil Steril. 109(3):380–388.e1

    Article  Google Scholar 

  19. Krentel H et al (2017) From clinical symptoms to MR imaging: diagnostic steps in adenomyosis. Biomed Res Int 2017:1514029

    Article  CAS  Google Scholar 

  20. Vannuccini S, Luisi S, Tosti C, Sorbi F, Petraglia F (2018) Role of medical therapy in the management of uterine adenomyosis. Fertil Steril. 109(3):398–405

    Article  Google Scholar 

  21. Zhang L, Rao F, Setzen R (2017) High intensity focused ultrasound for the treatment of adenomyosis: selection criteria, efficacy, safety and fertility. Acta Obstet Gynecol Scand. 96(6):707–714

    Article  Google Scholar 

  22. Lazzeri L, Morosetti G, Centini G, Monti G, Zupi E, Piccione E, Exacoustos C (2018) A sonographic classification of adenomyosis: interobserver reproducibility in the evaluation of type and degree of the myometrial involvement. Fertil Steril. 110(6):1154–1161.e3. https://doi.org/10.1016/j.fertnstert.2018.06.031

    Article  PubMed  Google Scholar 

  23. Rasmussen CK, Van den Bosch T, Exacoustos C, Manegold-Brauer G, Benacerraf BR, Froyman W, Landolfo C, Condorelli M, Egekvist AG, Josefsson H, Leone FPG, Jokubkiene L, Zannoni L, Epstein E, Installé A, Dueholm M (2019) Intra- and Inter-Rater Agreement Describing Myometrial Lesions Using Morphologic Uterus Sonographic Assessment: A Pilot Study. J Ultrasound Med. 38(10):2673–2683. https://doi.org/10.1002/jum.14971. Epub 2019 Feb 23

    Article  PubMed  Google Scholar 

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Correspondence to Elisabeth Janschek.

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E. Janschek gibt an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden von der Autorin keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

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Der Verlag bleibt in Hinblick auf geografische Zuordnungen und Gebietsbezeichnungen in veröffentlichten Karten und Institutsadressen neutral.

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Janschek, E. Adenomyose. J. Gynäkol. Endokrinol. AT 29, 76–85 (2019). https://doi.org/10.1007/s41974-019-00111-0

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  • DOI: https://doi.org/10.1007/s41974-019-00111-0

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