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New regenerative strategies in periodontics

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Abstract

The progressive inflammatory process, which leads to the destruction of the gingival connective tissue and subsequently of the alveolar bone, periodontal ligament (PDL), and cementum on the root surface, if left untreated will eventually lead to the loss of the involved tooth or implant. Regeneration of lost periodontal tissues has always been the primary goal of treatment; however, this has proven to be an extremely challenging task.

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Further Reading

  1. Weinreb M, Tsesis I, Rosen E, Taschieri S, Del Fabbro M, Nemcovsky CE. Evolving new strategies for periodontal, endodontic, and alveolar bone regeneration. In: Rosen E, Nemcovsky CE, Tsesis I (eds) Evidence-based decision making in dentistry. doi:10.1007/978-3-319-45733-8_8

  2. Sood S, Gupta S, Mahendra A (2012) Gene therapy with growth factors for periodontal tissue engineering a review. Med Oral Patol Oral Cir Bucal 17(2):e301–e310

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  4. Lin Z, Rios HF, Cochran DL (2015) Emerging regenerative approaches for periodontal reconstruction: a systematic review from the AAP Regeneration Workshop. J Periodontol 86(2 Suppl):S134–S152

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  5. Khoshkam V, Chan HL, Lin GH, Mailoa J, Giannobile WV, Wang HL, Oh TJ (2015) Outcomes of regenerative treatment with rhPDGF-BB and rhFGF-2 for periodontal intra-bony defects: a systematic review and meta-analysis. J Clin Periodontol 42(3):272–280

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Authors and Affiliations

  1. Department of Periodontology and Dental Implantology, School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel

    Carlos Ernesto Nemcovsky

  2. Department of Oral Biology, School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel

    Miron Weinreb

Authors
  1. Carlos Ernesto Nemcovsky
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  2. Miron Weinreb
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Correspondence to Carlos Ernesto Nemcovsky.

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Nemcovsky, C.E., Weinreb, M. New regenerative strategies in periodontics. Clin Dent Rev 1, 5 (2017). https://doi.org/10.1007/s41894-017-0005-1

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  • DOI: https://doi.org/10.1007/s41894-017-0005-1

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