Abstract
Myasthenia Gravis (MG) is a neuromuscular disease causing extreme muscular fatigue, triggering problems with vision, swallowing, speech, mobility, dexterity, and breathing. However, early detection and prediction of MG is a crucial and quite challenging task for medical practitioners. So, in our proposed work, we are focused on introducing an ontology-based intelligent system for the prognosis of patients affected by this neuromuscular disease. The given paper presents a novel framework that employs the concepts of ontology, semantic web rules, and reasoner for deriving whether the patient is tested positive or negative. The suggested framework's effectiveness is assessed by comparing it to machine learning classifiers using parameters from the NIH repository for Myasthenia Gravis. The experimental results show that the ontological-based framework is able to achieve higher accuracy (80.85%), higher precision (78.37%), and higher recall (76.55%) than the existing classifiers used in the recent studies.
Similar content being viewed by others
References
Mikhalskii AI, Novoseltseva JA (2018) Application of data analysis methods in research of neurodegenerative diseases. 2018 eleventh international conference "Management of large-scale system development" (MLSD, Moscow, Russia, 2018, pp. 1-4, doi: https://doi.org/10.1109/MLSD.2018.8551933
Erdaş ÇB, Sümer E (2020) A deep learning-based approach to detect neurodegenerative diseases. 2020 medical technologies congress (TIPTEKNO), Antalya, Turkey, 2020, pp. 1-4, doi: https://doi.org/10.1109/TIPTEKNO50054.2020.9299257
Swati S, Kumar M (2023) Analysis of multichannel neurophysiological signal for detecting epilepsy using deep-nets. Int J Inf Tecnol 15:1435–1441. https://doi.org/10.1007/s41870-023-01186-x
Anita S, Arokiadass R (2022) Mathematical model for early stage identification of Parkinson’s disease using neurotransmitter: GABA. Int J Inf Tecnol 14:265–273. https://doi.org/10.1007/s41870-021-00705-y
Deepak S, Ojha A, Acharjya K et al (2024) A novel and proposed triad machine learning-based framework for the prognosis of Huntington’s disease. Int J Inf Tecnol. https://doi.org/10.1007/s41870-023-01719-4
Boopathi M, Parikh S, Awasthi A et al (2024) OntoDSO: an ontological-based dolphin swarm optimization (DSO) approach to perform energy efficient routing in wireless sensor networks (WSNs). Int J Inf T ecnol 16:1551–1557. https://doi.org/10.1007/s41870-023-01698-6
Rasi RE, Namakavarani OM (2020) Organizational agility considering enablers and capabilities of agility with RBF neural network approach and multiple regressions. Int J Inf Tecnol. https://doi.org/10.1007/s41870-020-00492-y
Elden RH, Al-Atabany W, Ghoneim VF (2018) Gait variability analysis in neurodegenerative diseases using nonlinear dynamical modelling. 2018 9th Cairo international biomedical engineering conference (CIBEC), Cairo, Egypt, 2018, pp. 41-44, doi: https://doi.org/10.1109/CIBEC.2018.8641835
Liang T, Boulos MI, Murray BJ, Krishnan S, Katzberg H, Umapathy K (2016) Detection of myasthenia gravis using electrooculography signals. 2016 38th annual international conference of the IEEE engineering in medicine and biology society (EMBC), Orlando, FL, USA, pp. 896-899, doi: https://doi.org/10.1109/EMBC.2016.7590845
Qin S et al (2021) Application for measuring eyelid weakness in individuals with Myasthenia Gravis. 2021 IEEE global humanitarian technology conference (GHTC), Seattle, WA, USA, 2021, pp. 39-42, doi: https://doi.org/10.1109/GHTC53159.2021.9612418
Gilhus NE (2023) Myasthenia gravis, respiratory function, and respiratory tract disease. J Neurol 270:3329–3340. https://doi.org/10.1007/s00415-023-11733-y
Crisafulli S, Boccanegra B, Carollo M et al (2024) Myasthenia gravis treatment: from old drugs to innovative therapies with a glimpse into the future. CNS Drugs 38:15–32. https://doi.org/10.1007/s40263-023-01059-8
Agrawal S, Sahu SP (2024) Image-based Parkinson disease detection using deep transfer learning and optimization algorithm. Int j inf tecnol 16:871–879. https://doi.org/10.1007/s41870-023-01601-3
Hafer-Macko C, Naumes J, Macko R, Roy A (2016) Technology platform for tele-rehabilitation implementation in Mysathenia gravis at the point-of-care. 2016 IEEE healthcare innovation point-of-care technologies conference (HI-POCT), Cancun, Mexico. pp. 50–53, Doi: https://doi.org/10.1109/HIC.2016.7797694
Cicirelli G, Impedovo D, Dentamaro V, Marani R, Pirlo G, D’Orazio TR (2022) Human gait analysis in neurodegenerative diseases: a review. IEEE J Biomed Health Inform 26(1):229–242. https://doi.org/10.1109/JBHI.2021.3092875
Xu C, Neuroth T, Fujiwara T, Liang R, Ma K-L (2023) A predictive visual analytics system for studying neurodegenerative disease based on DTI fiber tracts. IEEE Trans Vis Comput Graph 29(4):2020–2035. https://doi.org/10.1109/TVCG.2021.3137174
Afshari FT, Parida A, Debenham P et al (2022) Myasthenia gravis complicating the surgical management of achondroplasia: a case-based update. Childs Nerv Syst 38:1855–1859. https://doi.org/10.1007/s00381-022-05617-1
Lakshmipriya B, Jayalakshmy S (2023) Wavelet scattering and scalogram visualization based human brain decoding using empirical wavelet transform. Int j inf tecnol 15:1699–1708. https://doi.org/10.1007/s41870-023-01213-x
https://www.ncbi.nlm.nih.gov/books/NBK559331/ (Accessed in April, 2024)
Gugliandolo G et al (2019) A movement-tremors recorder for patients of neurodegenerative diseases. IEEE Trans Instrum Meas 68(5):1451–1457. https://doi.org/10.1109/TIM.2019.2900141
Martins AS, Gromicho M, Pinto S, de Carvalho M, Madeira SC (2022) Learning prognostic models using disease progression patterns predicting the need for non-invasive ventilation in amyotrophic lateral sclerosis. IEEE/ACM Trans Comput Biol Bioinf 19(5):2572–2583. https://doi.org/10.1109/TCBB.2021.3078362
Agrawal S, Agrawal RK, Kumaran SS et al (2023) Fusion of 3D feature extraction techniques to enhance classification of spinocerebellar ataxia type 12. Int j inf tecnol. https://doi.org/10.1007/s41870-023-01579-y
Narula GS, Wason R, Jain V, Baliyan A (2018) Ontology mapping and merging aspects in semantic web. Int Rob Auto J 4(1):00087. https://doi.org/10.15406/iratj.2018.04.00087
Funding
The writers have not received any financial support from the public, commercial, or not-for-profit sectors.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
This study is not related with any conflicts of interest.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Mahajan, P., Agarwal, T., Vekariya, D. et al. OntoMG: a unique and ontological-based intelligent framework for early identification of myasthenia gravis (MG). Int. j. inf. tecnol. (2024). https://doi.org/10.1007/s41870-024-01908-9
Received:
Accepted:
Published:
DOI: https://doi.org/10.1007/s41870-024-01908-9