Nano-sized barium-doped hydroxyapatite (n-BaHA) was successfully synthesized by a facile one-pot mechanochemical process. The effect of dopant loading on phase composition and morphological features as well as hexagonal lattice constants was assessed to study structural evolution of the milled particles. From the XRD-Rietveld refinement, the a- and c-axis directions and unit cell volume showed an increasing trend with the increase of the dopant content. From the TEM observations, the doped nanopowders were composed of nanospheroids with an average particle size of 36 ± 2 nm. This novel top-down approach provides an outline for the future design of nanostructured bioceramics.
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This research was supported by the National Science Foundation (PREM center for interfaces, DMR-1205670), and the Robert A. Welch Foundation (AI-0045). The authors are also grateful to University of Malaya grant numbers: GC001C-14SBS and RP038C-15HTM, as well as Research Affairs of Islamic Azad University, Najafabad Branch, for supporting this research.
- Nano-sized Ba-doped HA was synthesized by a one-pot mechanochemical process.
- Structural changes during mechanical activation were investigated.
- Ba substitution increased the relative incorporation of CO3 2−.
- The doped powder was composed of nanospheroids with an average size of 36 ± 2 nm.
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Fahami, A., Nasiri-Tabrizi, B., Beall, G.W. et al. A top-down approach for the synthesis of nano-sized Ba-doped hydroxyapatite. J Aust Ceram Soc 53, 491–498 (2017). https://doi.org/10.1007/s41779-017-0059-1
- Ba-doped HA
- Rietveld refinement