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Chemical synthesis of chitosan (CS)–sodium alginate (ALG) nanoparticles

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Abstract

Alginate nanoparticles (CS/ALG) were synthesised via ionic-gelation of an alginate core, followed by polyelectrolyte-complexation of chitosan polymers. AG was diluted with distilled water before CaCl2 was added to enhance overall viscosity of the solution (solution 1). A 1% acetic acid solution was also used to dissolve CS (solution 2). Analysis of nanoparticles' morphology and structure was carried out using transmission electron microscopy as well as Fourier transform infrared spectroscopy (FTIR). The AG/CS NPs had distinct UV absorption spectra with a wavelength of 325 nm, which revealed the basic bandgap absorption of AG/CS nanocrystals XRD findings reveal that AG/CS-based samples had a single phase hexagonal wurtzite structure with no impurities FT-IR spectrum characteristics of AG/CS NPs indicate that the bonded N–H/C-H peaks may be assigned to 3442.39 cm−1. SEM photos in clearly showed the existence of spherical-shaped nanoparticles. AG/CS NPs ranged in size from 10 to 50 nm, with an average crystallite size of 15 nm.

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Correspondence to Deepa Bhagat.

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Srujana, S., Bhagat, D. Chemical synthesis of chitosan (CS)–sodium alginate (ALG) nanoparticles. Nanotechnol. Environ. Eng. 7, 289–296 (2022). https://doi.org/10.1007/s41204-022-00227-3

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