Skip to main content
SpringerLink
Log in

Porous ZnO/hydroxyapatite nanomaterials with effective photocatalytic and antibacterial activities for the degradation of antibiotics

Nanotechnology for Environmental Engineering volume 7, pages 333–341 (2022)Cite this article

Abstract

Simultaneous photocatalytic and antimicrobial activity is considered a very promising technology for water treatment. By studying their antimicrobial activity, the present study evaluates effect of the association of porous hydroxyapatite with zinc oxide to improve the photodegradation of antibiotics in water and to trap the by-products. Coexistence in the nanocomposite of zinc oxide with porous apatite, prepared from phosphate rock, is a key factor promoting strong photocatalytic and antibacterial activities. Toxicity of the water discharged after the photocatalytic treatment was studied. Owing to the simplicity of the synthesis of ZnO–hydroxyapatite nanocomposites from Moroccan natural phosphate and their versatility, the present approach holds promise for the development of multifunctional photocatalysts and antibacterial agents for environmental applications.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

USD 39.95

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9

References

  1. Simazaki D, Kubota R, Suzuki T, Akiba M, Nishimura T, Kunikane S (2015) Occurrence of selected pharmaceuticals at drinking water purification plants in Japan and implications for human health. Water Res. 76:187–200

    Article  Google Scholar 

  2. Rivera-Utrilla J, Sánchez-Polo M, Ferro-García MA, Prados-Joya G, Ocampo-Pérez R (2013) Pharmaceuticals as emerging contaminants and their removal from water: a review. Chemosphere 93:1268–1287

    Article  Google Scholar 

  3. Neppolian B, Sakthivel S, Arabindoo B, Palanichamy M, Murugesan V (1999) Degradation of textile dye by solar light using TiO2 and ZnO photocatalysts. J. Environ. Sci. Health Toxic/Hazard Part A 34:1829–1838

    Article  Google Scholar 

  4. El Bekkali C, Bouyarmane H, Saoiabi S, El Karbane M, Rami A, Saoiabi A, Boujtita M, Laghzizil A (2016) Low-cost composites based on porous titania-apatite surfaces for the removal of patent blue V from water: Effect of chemical structure of dye. J Adv Res 7:1009–1017

    Article  Google Scholar 

  5. Huber MM, Caninica S, Park GY, Gunten UV (2003) Oxidation of pharmaceuticals during ozonation and advanced oxidation processes. Environ Sci Technol 37:1016–1024

    Article  Google Scholar 

  6. Wang W, Zhijia Q, Zhu Z, Zhang L, Zhong S, Lieu B (2019) Enhanced photocatalytic degradation performance of organic contaminants by heterojunction photocatalyst BiVO4/TiO2/RGO and its compatibility on four different tetracycline antibiotics. Adv Powder Technol 30:1882–1896

    Article  Google Scholar 

  7. Heberer T, Reddersen K, Mechlinski A (2002) From municipal sewage to drinking water: fate and removal of pharmaceutical residues in the aquatic environment in urban areas. Water Sci Technol. 46:81–88

    Article  Google Scholar 

  8. Andreozzi A, Raffaele M, Nicklas P (2003) Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment. Chemosphere 50:1319–1330

    Article  Google Scholar 

  9. Jelic A, Gros M, Ginebreda M, Cespedes-Sánchez R, Ventura F, Petrovic M, Barcelo D (2011) Occurrence, partition and removal of pharmaceuticals in sewage water and sludge during wastewater treatment. Water Res 45:1165–1176

    Article  Google Scholar 

  10. Zhang H, Chen WR, Huang CH (2008) Kinetic modeling of oxidation of antibacterial agents by manganese oxide. Environ Sci Technol 42:5548–5554

    Article  Google Scholar 

  11. Figueroa RA, Leonard A, Mackay AA (2004) Modeling tetracycline antibiotic sorption to clays. Environ Sci Technol 38:476–483

    Article  Google Scholar 

  12. Carrasquillo AJ, Bruland GL, Mackay AA, Vasudevan D (2008) Sorption of ciprofloxacinand oxytetracycline zwitterions to soils and soil minerals: Influence of compound structure. Environ Sci Technol 42:7634–7642

    Article  Google Scholar 

  13. Shahzad K, Najam T, Bashir MS, Nazir MA, Rehman AU, Bashir MA, Shoaib S, Shah A (2021) Fabrication of periodic mesoporous organo silicate (PMOS) composites of Ag and ZnO: Photo-catalytic degradation of methylene blue and methyl orange. Inorg Chem Commun 123:108357

    Article  Google Scholar 

  14. Nakata K, Fujishima A (2012) TiO2 photocatalysis: design and applications. J Photochem Photobiol C Photochem Rev 13:169–189

    Article  Google Scholar 

  15. Liu J, Wang Y, Peng Y, Ma J, Wang A (2019) A review on bidirectional analogies between the photocatalysis and antibacterial properties of ZnO. J Alloys Compd 783:898–918

    Article  Google Scholar 

  16. Tobajas M, Belver C, Rodriguez JJ (2017) Degradation of emerging pollutants in water under solar irradiation using novel TiO2-ZnO/clay nanoarchitectures. Chem Eng J 309:596–606

    Article  Google Scholar 

  17. Parsai T, Kumar A (2020) Stability and characterization of mixture of three particle system containing ZnO-CuO nanoparticles and clay. Sci Total Environ Sci 740:140095

    Article  Google Scholar 

  18. Zheng H, Wu D, Wang Y, Liu X, Gao P, Liu W, Wen J, Rebrov EV (2020) One-step synthesis of ZIF-8/ZnO composites based on coordination defect strategy and its derivatives for photocatalysis. J Alloys Compd 838:155219

    Article  Google Scholar 

  19. El Bekkali C, Bouyarmane H, Karbane ML, Masse S, Saoiabi A, Coradin T, Laghzizil A (2018) Zinc oxide-hydroxyapatite nanocomposite photocatalysts for the degradation of ciprofloxacin and ofloxacin antibiotics. Colloids Surf A 539:364–370

    Article  Google Scholar 

  20. Abdelhamid HN, Bhaisare ML, Wu HF (2014) Ceria nanocubic-ultrasonication assisted dispersive liquid–liquid microextraction coupled with matrix assisted laser desorption/ionization mass spectrometry for pathogenic bacteria analysis. Talanta 120:208–217

    Article  Google Scholar 

  21. Gedda G, Abdelhamid HN, Khan MS, Wu HF (2014) ZnO nanoparticle-modified polymethyl methacrylate-assisted dispersive liquid–liquid microextraction coupled with MALDI-MS for rapid pathogenic bacteria analysis. RSC Adv. 4:45973–45983

    Article  Google Scholar 

  22. El Asri S, Laghzizil A, Saoiabi A, Alaoui A, El Abassi K, M’Hamdi K, Coradin T (2009) A novel process for the fabrication of nanoporousapatites from Moroccan phosphate rock. Colloids Surf A350:73–78

    Article  Google Scholar 

  23. Soussi L, Garmim T, Karzazi O, Rmili A, El Bachiri A, Louardi A, Erguig H (2020) Effect of (Co, Fe, Ni) doping on structural, optical and electrical properties of sprayed SnO2 thin film. Surf Interfaces 19:100467

    Article  Google Scholar 

  24. Manohar A, Park J, Geleta DD, Krishnamoorthi C, Thangam R, Kang H, Lee J (2021) Synthesis and characterization of ZnO nanoparticles for photocatalysis, antibacterial and cytotoxicity in kidney cancer (A498) cell lines. J Alloys Compd 874:159868

    Article  Google Scholar 

  25. Yamamoto O (2001) Influence of particle size on the antibacterial activity of zinc oxide. Int J Inorg Mater 3:643–646

    Article  Google Scholar 

  26. Paul D, Sutanu S, Dibya D, Sethi P, Neagi S (2021) Bi-functional NiO-ZnO nanocomposite: synthesis, characterization, antibacterial and photo assisted degradation study. Adv Powder Technol 32:131–143

    Article  Google Scholar 

  27. Joshi P, Chakraborti S, Chakrabarti P, Haranath D, Shanker V, Ansari Z, Singh SP, Gupta V (2009) Role of surface adsorbed anionic species in antibacterial activity of ZnO quantum dots against Escherichia coli. J Nanosci Nanotechnol 9:6427–6433

    Article  Google Scholar 

  28. Hsu A, Liu F, Leung YH, Ma AP, Djurišić AB, Leung FC, Chan WK, Lee HK (2014) Is the effect of surface modifying molecules on antibacterial activity universal for a given material? Nanoscale 6:10323–10331

    Article  Google Scholar 

  29. Kirkinezos IG, Moraes CT (2001) Reactive oxygen species and mitochondrial diseases. Semin Cell Dev Biol 12:449–457

    Article  Google Scholar 

  30. Song W, Zhang J, Guo J, Zhang J, Ding F, Li F, Sun Z (2010) Role of the dissolved zinc ion and reactive oxygen species in cytotoxicity of ZnO nanoparticles. Toxicol Lett 199:389–397

    Article  Google Scholar 

  31. Sirelkhatim A, Mahmud S, Seeni A, Kaus NHM, Ann LC, Bakhori SKM, Hasan H, Mohamad D (2015) Review on zinc oxide nanoparticles: antibacterial activity and toxicity mechanism. Nano-Micro Lett 7:219–242

    Article  Google Scholar 

  32. Kasemets K, Ivask A, Dubourguier HC, Kahru A (2009) Toxicity of nanoparticles of ZnO, CuO and TiO2 to yeast Saccharomyces cerevisiae. Toxicol In Vitro 23:1116–1122

    Article  Google Scholar 

  33. Padmavathy N, Vijayaraghavan R (2008) Enhanced bioactivity of ZnO nanoparticles-an antimicrobial study. Sci Technol Adv Mat 9:35004–35010

    Article  Google Scholar 

  34. Sawai J, Kawada E, Kanou F, Igarashi H, Hashimoto H, Kokugan T, Shimizu M (1996) Detection of active oxygen generated from ceramic powders having antibacterial activity. J Chem Eng Jpn 29:627–633

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratoire de Chimie appliqué des Matériaux, Faculté des Sciences, Université Mohammed V de Rabat, Av. Ibn Batouta, BP. 1014, Rabat, Morocco

    C. El Bekkali, J. Labrag, A. Oulguidoum & A. Laghzizil

  2. Center of Plant and Microbial Biotechnology, Biodiversity and Environment, Faculty of Sciences, Mohammed V University in Rabat, Rabat, Morocco

    I. Chamkhi & J. Aurag

  3. Department of Chemistry, Queen’s University, Kingston, ON, K7L 3N6, Canada

    J.-M. Nunzi

  4. Institut de Chimie et Procédés pour l’Energie, l’Environnement et la Santé (ICPEES), CNRS-UMR7515, Université de Strasbourg, Saint-Avold Antenna, Université de Lorraine, 12 Rue Victor Demange, 57500, Saint-Avold, France

    D. Robert

Authors
  1. C. El Bekkali
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Labrag
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. Oulguidoum
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. I. Chamkhi
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. A. Laghzizil
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. J.-M. Nunzi
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. D. Robert
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. J. Aurag
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to A. Laghzizil.

Ethics declarations

Conflict of interest

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. They have seen and approved the final version of the manuscript being submitted. They warrant that the article is the authors' original work, has not received prior publication, and is not under consideration for publication elsewhere. They also certify that they have no affiliations with or involvement in any organization or entity with any financial interest or non-financial interest in the subject matter or materials discussed in this manuscript.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and Permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

El Bekkali, C., Labrag, J., Oulguidoum, A. et al. Porous ZnO/hydroxyapatite nanomaterials with effective photocatalytic and antibacterial activities for the degradation of antibiotics. Nanotechnol. Environ. Eng. 7, 333–341 (2022). https://doi.org/10.1007/s41204-021-00172-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s41204-021-00172-7

Keywords

search

Navigation