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Age- and gender-related differences of CPAP acceptance for obstructive sleep apnea syndrome in Taiwan

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Abstract

In our previous study, we observed younger OSAS patients had higher CPAP acceptance but similar compliance as older OSAS patients, suggesting gender factor might play an important role on CPAP acceptance. Hence, we aimed to evaluate the influences of both gender and age on CPAP acceptance and compliance in Taiwanese OSAS patients. This retrospective study included 371 subjects which were subdivided by gender and age (younger: age < 55 years, and older: age ≥ 55 years) (n = 24 for younger women, n = 67 for older women, n = 131 for younger men; and n = 149 for older men). Anthropometric parameters, blood pressures, Epworth sleepiness scale, polysomnography variables, CPAP acceptance, and CPAP compliance were collected and compared. Univariate analysis evaluated the influence of different variables on CPAP acceptance. Due to the presence of multicollinearity for N3 sleep and AHI, as well as N3 sleep and DI, multivariate logistic regression models were conducted using three different models with N3 sleep, AHI, and DI included separately. Univariate analysis found women had less CPAP acceptance than men. Multivariate logistic regression analysis indicated younger women had lower CPAP acceptance, but in contrast younger men had higher CPAP acceptance. No difference was observed among the four subgroups for long-term CPAP compliance. In conclusion, our findings suggest that both age and gender impact CPAP acceptance for treating OSAS in Taiwan, with women having lower CPAP acceptance than men regardless of age. No apparent influence of age and gender on CPAP compliance was observed.

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Abbreviations

AHI:

Apnea/hypopnea index

CAD:

Coronary artery disease

CPAP:

Continuous positive airway pressure

CVD:

Cardiovascular disease

CVA:

Cerebrovascular accident

DBP:

Diastolic blood pressure

DI:

Desaturation index

EDS:

Excessive daytime sleepiness

EEG:

Electroencephalography

ESS:

Epworth sleepiness scale

HTN:

Hypertension

MAP:

Mean arterial pressure

OSAS:

Obstructive sleep apnea syndrome

PSG:

Polysomnography

REM:

Rapid eye movement

SaO2:

Oxygen saturation

SBP:

Systolic blood pressure

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Authors and Affiliations

  1. Division of Pulmonary Medicine, Department of Internal Medicine, Taipei Tzu-Chi Hospital, Buddhist Tzu Chi Medical Foundation, No. 289, Jianguo Rd., Xindian Dist., New Taipei City, 23142, Taiwan

    Yi-Chih Huang, Chou-Chin Lan, Yao-Kuang Wu, Wen-Lin Su & Mei-Chen Yang

  2. The School of Medicine, Tzu-Chi University, Hualien, Taiwan

    Yi-Chih Huang, Chou-Chin Lan, Yao-Kuang Wu, Wen-Lin Su & Mei-Chen Yang

Authors
  1. Yi-Chih Huang
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  2. Chou-Chin Lan
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  3. Yao-Kuang Wu
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  4. Wen-Lin Su
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Corresponding author

Correspondence to Mei-Chen Yang.

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Author contributions

Literature search: CCL and WLS; data collection: YCH and MCY; study design: MCY and YKW; analysis of data: MCY; manuscript preparation: YCH and MCY; review of manuscript: YKW and MCY. All authors read and approved the study.

Funding

The study was supported by a grant from the Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation (TCRD-TPE-106-RT-1).

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Ethical approval

The study was performed in accordance with the Declaration of Helsinki. The Institutional Review Board of the Taipei Tzuchi Hospital approved the protocol.

Informed consent

Since the study was retrospective in design, informed consent was not necessary.

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Huang, YC., Lan, CC., Wu, YK. et al. Age- and gender-related differences of CPAP acceptance for obstructive sleep apnea syndrome in Taiwan. Sleep Biol. Rhythms 16, 107–115 (2018). https://doi.org/10.1007/s41105-017-0132-8

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  • DOI: https://doi.org/10.1007/s41105-017-0132-8

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