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Rare Case of Ovarian Immature Teratoma with Gliomatosis Peritonei at Follow-Up: Dilemma with F-18 FDG PET CT Imaging

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Indian Journal of Gynecologic Oncology Aims and scope Submit manuscript

Abstract

Background

Gliomatosis peritonei (GP) is a rare condition, associated with immature teratomas, which are a type of germ cell tumors of the ovary. GP is essentially the presence of peritoneal and rarely thoracic implants with mature glial tissue. These lesions show up as contrast avid lesions with high SUV (standardized uptake value) on F-18 FDG PET/CT scans and are difficult to differentiate from residual/recurrent malignant lesions.

Objective

To focus on the role and limitations of F-18 FDG PET/CT in the diagnosis of gliomatosis peritonei.

Methods

We present a case of immature teratoma of the ovary with gliomatosis peritonei, which was diagnosed during follow-up after primary surgery and adjuvant chemotherapy. The diagnostic dilemma of the FDG avid lesions demonstrated during follow-up, and the steps taken to confirm the diagnosis are discussed.

Results

High SUV and contrast avid lesions were seen on follow-up PET/CT. Biopsy was performed and confirmed benign glial tissue.

Conclusions

Gliomatosis peritonei lesions show up as contrast avid lesions with high SUV (standardized uptake value) on F-18 FDG PET/CT scans. It is difficult to differentiate this benign tissue from residual/recurrent malignant lesions based on imaging only. Biopsy is often required to establish a diagnosis.

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Acknowledgements

We wish to sincerely thank the patient for consenting to share her case and the multidisciplinary team who were involved in the management of this case.

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Correspondence to Anbukkani Subbian.

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Subbian, A., Kamaleshwaran, K.K. & Ramkumar, E. Rare Case of Ovarian Immature Teratoma with Gliomatosis Peritonei at Follow-Up: Dilemma with F-18 FDG PET CT Imaging. Indian J Gynecol Oncolog 21, 46 (2023). https://doi.org/10.1007/s40944-023-00722-8

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  • DOI: https://doi.org/10.1007/s40944-023-00722-8

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