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Isolated Splenic Metastasis from Ovarian Carcinoma

  • Case Report
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Indian Journal of Gynecologic Oncology Aims and scope Submit manuscript



Isolated Splenic metastasis from ovarian cancer rarely occurs with only very few cases recorded in the literature. It can occur as a synchronous metastasis or as late as 20 years post-primary debulking surgery.

Case Report

A 62-year-old woman with carcinoma ovary stage IIIC was treated with primary debulking surgery in 2009, followed by six cycles of chemotherapy. In 2013, she was found to have an elevated serum CA-125 level during her regular follow-up. Imaging with CT scan abdomen showed a hyperdense lesion in splenic parenchyma of 2.1 × 2.4 cm. She underwent laparoscopic splenectomy. Histopathological examination revealed adenocarcinoma localised to the spleen, consistent with metastasis carcinoma ovary. Post-splenectomy, her CA-125 level returned to normal. Over the last 6 years, she is on regular follow-up and remains disease-free.


Isolated, solitary splenic metastasis from epithelial ovarian cancer is very rare. It occurred after a DFI of 4 years and was successfully treated and is remaining disease-free without any chemotherapy for the last 7 years.

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Correspondence to Keechilat Pavithran.

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Kumar, S.S., Nazarudeen, F., Rajanbabu, A. et al. Isolated Splenic Metastasis from Ovarian Carcinoma. Indian J Gynecol Oncolog 18, 98 (2020).

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