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Extra Uterine Choriocarcinoma Mimicking as Ectopic Pregnancy: A Rare Case Report

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Choriocarcinomas are germ cell tumours formed by trophoblastic elements (Mundkur et al., J Clin Diagn Res 9(1):QD01–2; 2015). Gestational choriocarcinoma can occur after molar pregnancy, tubal pregnancy or antecedent normal pregnancy. Primary extra-uterine choriocarcinoma is very rare.

Case Report

We report here a case of broad ligament choriocarcinoma who presented with a complaint of pain in lower abdomen off and on. She had a history of dilation and evacuation for spontaneous abortion 3 months back and then she had regular menses. Her transvaginal sonography revealed 42 x 35 mm size right adnexal mass which was more consistent with ectopic pregnancy and her serum human chorionic gonadotropin (β-Hcg) level was 1,76,075 mIU/ ml. Finally, patient was diagnosed as ruptured tubal ectopic pregnancy and thus, she underwent laparotomy. On laparotomy, there was purple colored broad ligament mass of size 5x6 cm with highly increased vascularity in right side which was removed with difficulty and massive bleeding occurred. So, total abdominal hysterectomy was done. Histopathological report showed choriocarcinoma of right broad ligament invading myometrium. The patient was given 6 cycles of EMACO regime. Serum β-Hcg levels of the patient gradually declined and eventually became negative after 2 weeks of 5th EMACO. With this case report, we aim to emphasize that while diagnosing the ectopic pregnancy, even very rare, the tubal choriocarcinoma should be kept in mind. We report a case of primary extra-uterine choriocarcinoma that was mistaken for an ectopic pregnancy.

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Correspondence to Sangeeta Pankaj.

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We declare that this manuscript is original, it has not been published anywhere before and is not currently being considered for publication elsewhere. We also confirm that the authors do not have any conflict of interest associated with publication of this work, and no significant financial support for this work has been received to influence the outcome. The manuscript is read and approved, and consent is given by all the authors. We give our permission to reproduce any material of the article.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. This article does not contain any studies with animals performed by any of the authors.

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Pankaj, S., Kumari, J., Nazneen, S. et al. Extra Uterine Choriocarcinoma Mimicking as Ectopic Pregnancy: A Rare Case Report. Indian J Gynecol Oncolog 16, 30 (2018).

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