Skip to main content
Log in

Extra Uterine Choriocarcinoma Mimicking as Ectopic Pregnancy: A Rare Case Report

  • Case report
  • Published:
Indian Journal of Gynecologic Oncology Aims and scope Submit manuscript

Abstract

Introduction

Choriocarcinomas are germ cell tumours formed by trophoblastic elements (Mundkur et al., J Clin Diagn Res 9(1):QD01–2; 2015). Gestational choriocarcinoma can occur after molar pregnancy, tubal pregnancy or antecedent normal pregnancy. Primary extra-uterine choriocarcinoma is very rare.

Case Report

We report here a case of broad ligament choriocarcinoma who presented with a complaint of pain in lower abdomen off and on. She had a history of dilation and evacuation for spontaneous abortion 3 months back and then she had regular menses. Her transvaginal sonography revealed 42 x 35 mm size right adnexal mass which was more consistent with ectopic pregnancy and her serum human chorionic gonadotropin (β-Hcg) level was 1,76,075 mIU/ ml. Finally, patient was diagnosed as ruptured tubal ectopic pregnancy and thus, she underwent laparotomy. On laparotomy, there was purple colored broad ligament mass of size 5x6 cm with highly increased vascularity in right side which was removed with difficulty and massive bleeding occurred. So, total abdominal hysterectomy was done. Histopathological report showed choriocarcinoma of right broad ligament invading myometrium. The patient was given 6 cycles of EMACO regime. Serum β-Hcg levels of the patient gradually declined and eventually became negative after 2 weeks of 5th EMACO. With this case report, we aim to emphasize that while diagnosing the ectopic pregnancy, even very rare, the tubal choriocarcinoma should be kept in mind. We report a case of primary extra-uterine choriocarcinoma that was mistaken for an ectopic pregnancy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Mundkur A, Rai L, Hebbar S, Guruvare S, Adiga P. Fallopian tube choriocarcinoma presenting as ovarian tumour: a case report. J Clin Diagn Res. 2015;9(1):QD01–2.

    PubMed  PubMed Central  Google Scholar 

  2. Shanbhogue AK, Fasih N, Macdonald DB, Sheikh AM, Menias CO, Prasad SR. Uncommon primary pelvic retroperitoneal masses in adults: a pattern-based imaging approach. RadioGraphics. 2012;32(3):795–817.

    Article  PubMed  Google Scholar 

  3. Mitrovic SLJ, Arsenijevic PS, Kljakic D, Djuric JM, Milosavljevic MZ, Protrka ZM, et al. Gestational choriocarcinoma of the cervix. Arch Iran Med. 2014;17(11):783–5.

    PubMed  Google Scholar 

  4. Nayama M, Lucot JP, Boukerrou M, Collinet P, Cosson M, Vinatier D. Tubal choriocarcinoma: a case report and review of the literature. J Gynecol Obstet Biol Reprod (Paris). 2007;36(1):83–6.

    Article  CAS  Google Scholar 

  5. Rettenmaier MA, Khan HJ, Epstein HD, Nguyen D, Abaid LN, Goldstein BH. Gestational choriocarcinoma in the fallopian tube. J Obstet Gynaecol. 2013;33(8):912–4.

    Article  PubMed  CAS  Google Scholar 

  6. Speroff L, Fritz MA. Clinical gynecologic endocrinology and infertility. 7th ed. Philadelphia: Lippinocott Williams & Wilkins; 2005. p. 1281–8.

    Google Scholar 

  7. Nakayama M, Namb A, Yasuda M, Hara M, Hara M, Ishihara O, Itakura A. Gestational choriocarcinoma of Fallopian tube diagnosed with a combination of p57KIP immunostaining and short tandem repeat analysis: case report. J Obstet Gynaecol Res. 2011;37(10):1493–6.

    Article  PubMed  Google Scholar 

  8. Ubayasiri K, Hancock B, Duncan T. A case of primary choriocarcinoma of the fallopian tube. J Obstet Gynaecol. 2010;30:881–3.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sangeeta Pankaj.

Ethics declarations

Conflict of interest

We declare that this manuscript is original, it has not been published anywhere before and is not currently being considered for publication elsewhere. We also confirm that the authors do not have any conflict of interest associated with publication of this work, and no significant financial support for this work has been received to influence the outcome. The manuscript is read and approved, and consent is given by all the authors. We give our permission to reproduce any material of the article.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. This article does not contain any studies with animals performed by any of the authors.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Pankaj, S., Kumari, J., Nazneen, S. et al. Extra Uterine Choriocarcinoma Mimicking as Ectopic Pregnancy: A Rare Case Report. Indian J Gynecol Oncolog 16, 30 (2018). https://doi.org/10.1007/s40944-018-0199-4

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s40944-018-0199-4

Keywords

Navigation